Results 21 to 30 of about 19,338 (133)

A Baculovirus immediate-early gene, ie1, promoter drives efficient expression of a transgene in both Drosophila melanogaster and Bombyx mori. [PDF]

open access: yesPLoS ONE, 2012
Many promoters have been used to drive expression of heterologous transgenes in insects. One major obstacle in the study of non-model insects is the dearth of useful promoters for analysis of gene function.
Mika Masumoto   +4 more
doaj   +1 more source

Revisiting promyelocytic leukemia protein targeting by human cytomegalovirus immediate-early protein 1.

open access: yesPLoS Pathogens, 2020
Promyelocytic leukemia (PML) bodies are nuclear organelles implicated in intrinsic and innate antiviral defense. The eponymous PML proteins, central to the self-organization of PML bodies, and other restriction factors found in these organelles are ...
Christina Paulus   +6 more
doaj   +1 more source

A nonstructural polypeptide encoded by immediate-early transcription unit 1 of murine cytomegalovirus is recognized by cytolytic T lymphocytes [PDF]

open access: yes, 1987
We have constructed target cells by cotransfection of the MHC gene Ld and fragments of murine cytomegalovirus (MCMV) DNA coding for nonstructural immediate-early (IE) proteins.
Keil, Günther M.   +4 more
core   +2 more sources

Location, transcripts, and translation products [PDF]

open access: yes, 1987
Cloned genomic fragments from the region (0.769 to 0.818 map units) coding for immediate-early (IE) transcripts of murine cytomegalovirus (MCMV) were used to analyze the physical organization of this region, the direction of transcription, and the ...
Ebeling-Keil, Angelika   +2 more
core   +1 more source

The Carboxy Terminal Region of the Human Cytomegalovirus Immediate Early 1 (IE1) Protein Disrupts Type II Inteferon Signaling

open access: yesViruses, 2014
Interferons (IFNs) activate the first lines of defense against viruses, and promote innate and adaptive immune responses to viruses. We report that the immediate early 1 (IE1) protein of human cytomegalovirus (HCMV) disrupts signaling by IFNγ.
Bindu Raghavan   +2 more
doaj   +1 more source

Identification of Cellular Proteins that Interact with Human Cytomegalovirus Immediate-Early Protein 1 by Protein Array Assay

open access: yesViruses, 2013
Human cytomegalovirus (HCMV) gene expression during infection is characterized as a sequential process including immediate-early (IE), early (E), and late (L)-stage gene expression.
Francisco Puerta Martínez, Qiyi Tang
doaj   +1 more source

Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers.

open access: yesPLoS Pathogens, 2021
Restriction factors are potent antiviral proteins that constitute a first line of intracellular defense by blocking viral replication and spread. During co-evolution, however, viruses have developed antagonistic proteins to modulate or degrade the ...
Johannes Schweininger   +6 more
doaj   +1 more source

Positive role of promyelocytic leukemia protein in type I interferon response and its regulation by human cytomegalovirus. [PDF]

open access: yesPLoS Pathogens, 2015
Promyelocytic leukemia protein (PML), a major component of PML nuclear bodies (also known as nuclear domain 10), is involved in diverse cellular processes such as cell proliferation, apoptosis, gene regulation, and DNA damage response. PML also acts as a
Young-Eui Kim, Jin-Hyun Ahn
doaj   +1 more source

Minimal free resolutions and asymptotic behavior of multigraded regularity [PDF]

open access: yes, 2007
Let S be a standard N^k-graded polynomial ring over a field. Let I be a multigraded homogeneous ideal in S and let M be a finitely generated Z^k-graded S-module.
Ha, Huy Tai, Strunk, Brent
core   +2 more sources

Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]

open access: yes, 2001
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Berencsi, Klára   +11 more
core   +1 more source

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