Results 21 to 30 of about 19,338 (133)
A Baculovirus immediate-early gene, ie1, promoter drives efficient expression of a transgene in both Drosophila melanogaster and Bombyx mori. [PDF]
Many promoters have been used to drive expression of heterologous transgenes in insects. One major obstacle in the study of non-model insects is the dearth of useful promoters for analysis of gene function.
Mika Masumoto+4 more
doaj +1 more source
Promyelocytic leukemia (PML) bodies are nuclear organelles implicated in intrinsic and innate antiviral defense. The eponymous PML proteins, central to the self-organization of PML bodies, and other restriction factors found in these organelles are ...
Christina Paulus+6 more
doaj +1 more source
A nonstructural polypeptide encoded by immediate-early transcription unit 1 of murine cytomegalovirus is recognized by cytolytic T lymphocytes [PDF]
We have constructed target cells by cotransfection of the MHC gene Ld and fragments of murine cytomegalovirus (MCMV) DNA coding for nonstructural immediate-early (IE) proteins.
Keil, Günther M.+4 more
core +2 more sources
Location, transcripts, and translation products [PDF]
Cloned genomic fragments from the region (0.769 to 0.818 map units) coding for immediate-early (IE) transcripts of murine cytomegalovirus (MCMV) were used to analyze the physical organization of this region, the direction of transcription, and the ...
Ebeling-Keil, Angelika+2 more
core +1 more source
Interferons (IFNs) activate the first lines of defense against viruses, and promote innate and adaptive immune responses to viruses. We report that the immediate early 1 (IE1) protein of human cytomegalovirus (HCMV) disrupts signaling by IFNγ.
Bindu Raghavan+2 more
doaj +1 more source
Human cytomegalovirus (HCMV) gene expression during infection is characterized as a sequential process including immediate-early (IE), early (E), and late (L)-stage gene expression.
Francisco Puerta Martínez, Qiyi Tang
doaj +1 more source
Restriction factors are potent antiviral proteins that constitute a first line of intracellular defense by blocking viral replication and spread. During co-evolution, however, viruses have developed antagonistic proteins to modulate or degrade the ...
Johannes Schweininger+6 more
doaj +1 more source
Positive role of promyelocytic leukemia protein in type I interferon response and its regulation by human cytomegalovirus. [PDF]
Promyelocytic leukemia protein (PML), a major component of PML nuclear bodies (also known as nuclear domain 10), is involved in diverse cellular processes such as cell proliferation, apoptosis, gene regulation, and DNA damage response. PML also acts as a
Young-Eui Kim, Jin-Hyun Ahn
doaj +1 more source
Minimal free resolutions and asymptotic behavior of multigraded regularity [PDF]
Let S be a standard N^k-graded polynomial ring over a field. Let I be a multigraded homogeneous ideal in S and let M be a finitely generated Z^k-graded S-module.
Ha, Huy Tai, Strunk, Brent
core +2 more sources
Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Berencsi, Klára+11 more
core +1 more source