Results 31 to 40 of about 19,338 (133)

The Core Histone-binding Region of the Murine Cytomegalovirus 89K Immediate Early Protein [PDF]

, 1991
The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA-associated and isolated histones in vitro. We characterized the histone-binding region of pp89 and its cellular localization during cell division to ...
Bühler, Bernhard, Koszinowski, Ulrich H., Messerle, Martin, Münch, Konrad   +3 more
core   +1 more source

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection.

PLoS Pathogens, 2012
Little is known about the role of viral genes in modulating host cytokine responses. Here we report a new functional role of the viral encoded IE1 protein of the murine cytomegalovirus in sculpting the inflammatory response in an acute infection. In time
Sara Rodríguez-Martín, Kai Alexander Kropp, Vanessa Wilhelmi, Vanda Juranic Lisnic, Wei Yuan Hsieh, Mathieu Blanc, Andrew Livingston, Andreas Busche, Hille Tekotte, Martin Messerle, Manfred Auer, Iain Fraser, Stipan Jonjic, Ana Angulo, Matthias J Reddehase, Peter Ghazal   +15 more
doaj   +1 more source

An acidic region of the 89K murine cytomegalovirus immediate early protein interacts with DNA [PDF]

, 1992
The product of the ie 1 gene, the regulatory immediate early protein pp89 of murine cytomegalovirus (MCMV), interacts with core histones, which can mediate the association of pp89 with DNA.
Koszinowski, Ulrich H., Messerle, Martin, Münch, Konrad, Plachter, Bodo   +3 more
core   +1 more source

WSSV ie1 promoter is more efficient than CMV promoter to express H5 hemagglutinin from influenza virus in baculovirus as a chicken vaccine

BMC Microbiology, 2008
Background The worldwide outbreak of influenza A (H5N1) viruses among poultry species and humans highlighted the need to develop efficacious and safe vaccines based on efficient and scaleable production. Results White spot syndrome virus (WSSV) immediate-
Yu Li, Ho YuenFern, He Fang, Kwang Jimmy
doaj   +1 more source

Presentation of CMV immediate-early antigen to cytolytic T lymphocytes is selectively prevented by viral genes expressed in the early phase [PDF]

, 1989
The regulation of antigen processing and presentation to MHC class I-restricted cytolytic T lymphocytes was studied in cells infected with murine cytomegalovirus. Recognition by cytolytic T lymphocytes of the phosphoprotein pp89, the immunodominant viral
Bernards, Borysiewicz, Braciale, Burgert, Cochet, Coupar, De Plaen, Del Val, Ebeling, Germain, Germain, Gooding, Gregory, Haddada, Hansen, Jennings, Jonjic, Keil, Keil, Keil, Konrad Münch, Koszinowski, Koszinowski, Kotwal, Lemke, Lurquin, Margarita Del Val, Maryanski, Masucci, Matthias J. Reddehase, Reddehase, Reddehase, Reddehase, Reddehase, Reddehase, Rice, Schickendanz, Schrier, Schwartz, Shimonkevitz, Stinski, Tanaka, Townsend, Townsend, Townsend, Ulrich H. Koszinowski, Vaessen, Volkmer, Yewdell   +48 more
core   +1 more source

Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γ. [PDF]

PLoS Pathogens, 2011
Human cytomegalovirus (hCMV) is a highly prevalent pathogen that, upon primary infection, establishes life-long persistence in all infected individuals.
Theresa Knoblach, Benedikt Grandel, Jana Seiler, Michael Nevels, Christina Paulus   +4 more
doaj   +1 more source

Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells

Journal of Translational Medicine, 2008
Background Recent studies demonstrate that recombinant adeno-associated virus (rAAV)-based antigen loading of dendritic cells (DCs) generates in vitro, significant and rapid cytotoxic T-lymphocyte (CTL) responses against viral antigens.
Dalle-Donne Isabella, Cannon Martin, Milzani Aldo, Bumm Klaus, Gagliano Nicoletta, Jenkins Marjorie, Zhou Wei, Yan Juqiang, Pilgrim Petra, Yu Yuefei, Kast W Martin, Cobos Everardo, Chiriva-Internati Maurizio   +12 more
doaj   +1 more source

Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente [PDF]

, 2001
Tumor necrosis factor (TNF)-related cytokines regulate cell death and survival and provide strong selective pressures for viruses, such as cytomegalovirus (CMV), to evolve counterstrategies in order to persist in immune-competent hosts.
Angulo, A, Banks, T A, Benedict, C A, Britt, W J, Ghazal, P, Ko, M, Senderowicz, L, Ware, C F   +7 more
core   +1 more source

Sf-PHB2, A new transcription factor, Drives WSSV Ie1 Gene Expression via a 12-bp DNA Element

Virology Journal, 2012
Background The WSSV immediate early gene ie1 is highly expressed throughout viral infection cycle and may play a central role in initiating viral replication during infection.
Ma Guoda, Yu Li, Wang Qian, Liu Wei, Cui Yudong, Kwang Jimmy   +5 more
doaj   +1 more source

3-dimensional Rules for Finite-Temperature Loops [PDF]

, 1997
We present simple diagrammatic rules to write down Euclidean n-point functions at finite temperature directly in terms of 3-dimensional momentum integrals, without ever performing a single Matsubara sum.
Balian, Barton, Baym, Braaten, C. Dib, Dzyaloshinski, Frenkel, Guerin, I. Schmidt, Landsman, O. Espinosa, Pisarski, Schweber, Weldon   +13 more
core   +2 more sources