Results 1 to 10 of about 90,591 (157)

Low dose IFNγ remodels enhancer landscape to potentiate mesenchymal stromal cell activation. [PDF]

Stem Cell Res Ther
Lin J, Ruan D, Hu Q, Cao X, Zhou W, Hu S.   +5 more
europepmc   +3 more sources

IFNγ signaling drives resistance to FLT3 inhibition in acute myeloid leukemia. [PDF]

iScience
Khouqeer A, Cartailler J, Kim C, Dickerson KM, Potts CR, Gilbert AE, Welner RS, Ferrell PB.   +7 more
europepmc   +2 more sources

Type 1–type 2 interferon imbalance in dry eye disease

Indian Journal of Ophthalmology, 2023
Purpose: Dry eye disease (DED) is characterized by altered ocular surface proinflammatory and antiinflammatory factors. Interferons (IFNs) are a class of pleiotropic cytokines well known for their antimicrobial, inflammatory, and immunomodulatory roles ...
Trailokyanath Panigrahi, Sharon D'Souza, Vishnu Suresh Babu, Mor M Dickman, Rudy M M A Nuijts, Swaminathan Sethu, Rohit Shetty   +6 more
doaj   +1 more source

HERPESVIRUS INFECTIONS AND CLINICAL-IMMUNOLOGIC INTERACTIONS IN PATIENTS WITH EARLY-ONSET ALZHEIMER’S DISEASE AND LATE-ONSET ALZHEIMER’S DISEASE

Медицинская иммунология, 2021
Alzheimer’s disease (AD) is currently the most common cause of dementia. A significant role in the pathogenesis of AD belongs to the activation of the mechanisms of neuroinflammation.
I. K. Malashenkova, D. P. Ogurtsov, S. A. Krynskiy, N. A. Khailov, N. D. Selezneva, Ya. B. Fedorova, E. V. Ponomareva, I. V. Kolykhalov, S. I. Gavrilova, N. A. Didkovsky   +9 more
doaj   +1 more source

γδT cells in patients with tumors of the nasal cavity and paranasal sinuses

Медицинская иммунология, 2023
The immunological factors can play an important role as predictive and prognostic biomarkers in oncopathology. Recently, non-conventional innate-like γδT-lymphocytes have received a lot of attention as a promising effector cell population for cancer ...
D. B. Nizheharodava, J. V. Kolyadich, N. A. Marozava, M. M. Zafranskaya   +3 more
doaj   +1 more source

Influence of acute cold stress on the secretion of IL-2, IL-4, IFNγ, IL-12 in vivo by mouse splenocytes

Медицинская иммунология, 2022
Current literature contains a large amount of data on the modifying effect of cold stress on the functions of immune cell system, in particular, on the secretion of cytokines by the cells of innate and adaptive immunity, mRNA expression.
I. L. Sharav’eva, S. V. Gein
doaj   +1 more source

اثرات عصاره ی سیر بر بیان ژن‌های IFNγ، IL-17F و IL-17A در سلول‌های تک هسته‌ای خون محیطی در بیماری Multiple Sclerosis [PDF]

مجله دانشکده پزشکی اصفهان, 2022
مقاله پژوهشیمقدمه: گیاه سیر، دارای ترکیبات استروئیدی ساپونینی با قابلیت مهار برخی واکنش‌های ایمنی مانند التهاب و تکثیر مونوسیت‌هاست. با توجه به اهمیت لنفوسیت‌های Th1 و Th17 در پاتوژنز بیماری (Multiple sclerosis) MS، و اثرات ساپونین‌ها بر تعدیل سیستم ...
غزل رادپرور, مسعود صادقی دینانی, ناهید اسکندری, نسرین زارع, وحید شایگان‌نژاد, علی جهانیان نجف‌آبادی   +5 more
doaj   +1 more source

Experimental evaluation of polymer construction materials: effects of acrylic resin and a fiberglass-based composite upon cytokine production

Медицинская иммунология, 2022
Polymethyl methacrylate-based acrylic resin is commonly used in current dental practice as an underlying material for fabrication of overdenture restorations.
A. P. Godovalov, A. B. Astashina, A. A. Bazhin, T. A. Drokina   +3 more
doaj   +1 more source

Low T cell production of TNFα and IFNγ in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism [PDF]

Annals of the Rheumatic Diseases, 2001
To test the hypothesis that ankylosing spondylitis (AS) is a T helper cell type 2 polarised disease by quantifying the T cell cytokines interferon gamma (IFNgamma), interleukin 4 (IL4), tumour necrosis factor alpha (TNFalpha), and IL10 at the single cell level in patients with AS in comparison with healthy HLA-B27 negative and HLA-B27 positive controls.
M, Rudwaleit, S, Siegert, Z, Yin, J, Eick, A, Thiel, A, Radbruch, J, Sieper, J, Braun   +7 more
openaire   +2 more sources

Role of IFNγ in pathogenesis of SARS-CoV-2 infection

Медицинская иммунология, 2022
To date, there is no consensus explaining the relationship between varying concentrations of IFNγ and the severity of infection caused by SARS-CoV-2.
A. A. Artamonov, Yu. V. Nikitin, M. E. Meshkova, A. M. Ivanov   +3 more
doaj   +1 more source