Results 181 to 190 of about 140,805 (301)

Figure 5 from IFNγ Production by Functionally Reprogrammed Tregs Promotes Antitumor Efficacy of OX40/CD137 Bispecific Agonist Therapy

Charlotte J. Imianowski, Paula Kuo, Sarah K. Whiteside, Teresa von Linde, Alexander J. Wesolowski, Alberto G. Conti, Alexander C. Evans, Tarrion Baird, Benjamin I. Morris, Nicole E. Fletcher, Jie Yang, Edmund Poon, Matthew A. Lakins, Masahiro Yamamoto, Neil Brewis, Michelle Morrow, Rahul Roychoudhuri   +16 more
openalex   +1 more source

IFNγ Influences Type I Interferon Response and Susceptibility to Theiler's Virus-Induced Demyelinating Disease

, 2013
Jenna L. Bowen, Julie K. Olson
openalex   +1 more source

Variability between countries in cytokine responses to BCG vaccination: what impact might this have on protection?

, 2012
Dockrell, Hazel M, Lalor, Maeve K, Smith, Steven G   +2 more
core   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Data from Central Role of IFNγ–Indoleamine 2,3-Dioxygenase Axis in Regulation of Interleukin-12–Mediated Antitumor Immunity

, 2023
Tao Gu, Rachael B. Rowswell-Turner, Mehmet O. Kilinc, Nejat K. Egilmez   +3 more
openalex   +1 more source

Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines. [PDF]

, 2015
Altmann, DM, Ascough, S, Baillie, L, Boyton, RJ, Doganay, M, Ingram, RJ, Maillere, B, Metan, G, Reynolds, CJ, Robinson, JH, Williamson, DE   +10 more
core   +1 more source

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

American Journal of Hematology, EarlyView.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong, Tamara Wais, Cecilia Varga, Christina Schueller, Sarada Achyutuni, Robert Kralovics   +5 more
wiley   +1 more source

Data from IFNγ-Dependent Interactions between ICAM-1 and LFA-1 Counteract Prostaglandin E2–Mediated Inhibition of Antitumor CTL Responses

, 2023
Fatemah Basingab, Maryam Ahmadi, David J. Morgan   +2 more
openalex   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

RIPK1 regulates β-cell fate via actions on gene expression and kinase signaling in a mouse model of β-cell self-reactivity. [PDF]

Cell Death Dis
Contreras CJ, Mukherjee N, Harris-Kawano A, Mather EG, Amarsaikhan N, Davis C, Berryhill CA, Peyton M, Kundu D, Colglazier KA, Miller AS, Branco RCS, Johnson TS, Angus SP, You S, Cai EP, Templin AT.   +16 more
europepmc   +1 more source