Ablation of IFNγ enhances hepatocarcinogenesis by promoting activation of STAT3 and JNK
Zhipeng Meng
openalex +1 more source
1) Nanostructured lipid carriers efficiently vectorize low‐immunogenic M2e peptide. 2) M2e peptide conjugation via click chemistry preserves the peptide key epitopes. 3) Forty M2e peptides per nanoparticle are sufficient to induce robust immune responses.
Louis Bourlon +7 more
wiley +1 more source
IL17F<sup>+</sup> naïve and IFNγ<sup>+</sup> memory CD8 T cells drive hepatic dysfunction in the cecal ligation and puncture model of sepsis. [PDF]
Taylor MD +9 more
europepmc +1 more source
THE IFNγ RECEPTOR:A Paradigm for Cytokine Receptor Signaling
Erika A Bach +2 more
openalex +2 more sources
Premature infants have impaired airway antiviral IFNγ responses to human metapneumovirus compared to respiratory syncytial virus [PDF]
Krishna Pancham +8 more
openalex +1 more source
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Long-term memory in epithelia: transient IFNγ exposure drives stable repression of TFF1 in gastric epithelial cells via epigenetic changes. [PDF]
Voli A +10 more
europepmc +1 more source
IFNγ Induces FOXP3+ Treg Dysfunction to Promote Antitumor Immunity [PDF]
openalex +1 more source
Objective Pain is the hallmark symptom of osteoarthritis (OA), and its biologic drivers remain poorly understood. Although the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular Treg cells, is not well understood.
Marie Binvignat +26 more
wiley +1 more source
The early human interferon gamma response to Toxoplasma gondii is driven by Vγ9Vδ2 T-cell sensing of host phosphoantigens and subsequent NK-cell activation. [PDF]
Rodriguez F, Saeij JPJ.
europepmc +1 more source

