Results 221 to 230 of about 140,805 (301)

Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications

Exploration, EarlyView.
Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu, Yi Li, Hulin Long, Yijia Wu, Ningwei Sun, Shun Li, Yiyao Liu, Huiqi Xie, Ji Bao   +8 more
wiley   +1 more source

Intranasal BCG vaccination induces systemic and pulmonary mucosal immune responses against tuberculosis in a goat model. [PDF]

Front Immunol
Cuenca-Lara P, Blay-Benach M, Cervera Z, Moraleda J, Sevilla IA, Garrido JM, Singh M, López-Soria S, Vidal E, Domingo M, Pérez de Val B.   +10 more
europepmc   +1 more source

Immunosuppressive Microenvironment Reprogramming by Synergistic Sonodynamic Therapy of Phthalocyanine‐MOF Hybrids for Hepatocellular Carcinoma

Exploration, EarlyView.
Hepatocellular carcinoma presents a formidable clinical challenge, constructing a hypoxic and immunosuppressive microenvironment that renders conventional therapies largely ineffective. In response, we have developed Pc@Zr‐MOF, a phthalocyanine‐integrated metal‐organic framework hybrid engineered to penetrate this defensive barrier.
Han Wu, Lihui Gu, Jiahao Xu, Chuyue Zhang, Mingda Wang, Chao Li, Lanqing Yao, Yongkang Diao, Yuchen Li, Fujie Chen, Huixuan Fan, Yuze Zhao, Feng Shen, Tian Yang   +13 more
wiley   +1 more source

Anti-interferon-γ Autoantibodies and Indeterminate QuantiFERON^Ⓡ-TB Gold Plus Assays. [PDF]

Open Forum Infect Dis
Lee S, Harris AJ, Zerbe CS, Walworth C, Naides SJ, Holland SM, Rosen LB.   +6 more
europepmc   +1 more source

Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy

Exploration, EarlyView.
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang, Huizhen Yang, Guoping Jia, Wangxi Hai, Rongyi Huang, Peng Wang, Min Zhang, Danni Li, Yizhou Chen, Xiao Li, Biao Li, Chunfu Zhang   +11 more
wiley   +1 more source

Correction to: Anti-interferon-γ Autoantibodies and Indeterminate QuantiFERON^Ⓡ-TB Gold Plus Assays. [PDF]

Open Forum Infect Dis
europepmc   +1 more source

Radiotherapy enhances M1 macrophage immunogenic activity through IFNs induction and stimulation in TP53-wild type tumors. [PDF]

Cancer Immunol Immunother
Cheng CC, Yeh HZ, Sie ZL, Wang CL, Peng CL, Ho AS, Wang CI, Chang CC.   +7 more
europepmc   +1 more source

IFNγ influences epithelial proliferation by modulating Akt-β catenin signaling downstream of cadherins [PDF]

, 2011
Porfirio Nava‐Dominguez, Keli Kolegraff, Charles A. Parkos, Asma Nusrat   +3 more
openalex   +1 more source

Genomic and Immune Correlates of EZH2 Expression and Activity in Olfactory Neuroblastoma

Head &Neck, EarlyView.
ABSTRACT Purpose Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy with limited therapeutic options in the recurrent/metastatic setting; little is known regarding its responsiveness to immunotherapy. Inhibition of enhancer of zeste homolog 2 (EZH2) has been shown to improve T‐cell‐mediated killing and susceptibility to immune checkpoint ...
Elisabetta Xue, Tolulope Adeyelu, Harris Krause, Andrew Elliott, Ranee Mehra, Heloisa Soares, Emil Lou, Ari Vanderwalde, David Spetzler, Dara Bracken‐Clarke, Nyall R. London Jr., James L. Gulley, Charalampos S. Floudas   +12 more
wiley   +1 more source

CXCL9 and CXCL10 Induce Expression of Nociceptive Ion Channels in Primary Sensory Neurons in Models of HIV-Associated Distal Sensory Polyneuropathy. [PDF]

Int J Mol Sci
Warfield R, Robinson JA, Baak S, Podgorski RM, Gabor TA, Caocci M, Niu M, Miller AD, Fox HS, Burdo TH.   +9 more
europepmc   +1 more source