Results 11 to 20 of about 502,516 (332)
Cleveland Clinic Journal of Medicine, 2023 Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis in the world. The etiology is unknown but a dysregulated T-cell immune response to viral, bacterial, and food antigens activating mucosal plasma cells to produce polymeric IgA has been proposed. No serological test exists to diagnosis IgAN.
Jonathan J, Taliercio, Ali, Mehdi
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Annual Review of Medicine, 1987 IgA nephropathy is a syndrome and probably the most important glomerular disease in terms of incidence and mortality. This review documents the clinical and pathological features and concentrates on the evolving thoughts regarding pathogenesis and treatment.
A R, Clarkson +4 more
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Nature Reviews Disease Primers, 2016 Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but current biochemical and genetic data implicate overproduction of aberrantly glycosylated IgA1.
Schena, FP +6 more
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IgA Glycosylation in IgA Nephropathy [PDF]
, 1998 IgA nephropathy (IgAN) is the commonest form of glomerulonephritis in developed countries where renal biopsy is widely practiced1. IgAN is defined by the deposition of IgA in the glomerular mesangium. Most typically, patients present with episodes of visible haematuria, which often concide with respiratory or gastrointestinal infection.
A, Allen, J, Feehally
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From contrastive rhetoric to intercultural rhetoric: Why intercultural rhetoric needs to reframe the concept of culture [PDF]
, 2013 Udostępnienie publikacji Wydawnictwa Uniwersytetu Łódzkiego finansowane w ramach projektu „Doskonałość naukowa kluczem do doskonałości kształcenia”. Projekt realizowany jest ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego ...
Lehman, Iga
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IgA subclass and IgA deficiency
Japanese Journal of Clinical Immunology, 2009 There are two subclasses of IgA, IgA1 and IgA2, and its heavy chains are encoded by two different genes, alpha1 and alpha2 genes. These two subclasses play important roles in the first line of defense, and the amount ratio of these molecules in secretions varies.
Hideo, Kaneko +2 more
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Polyclonal Antibody Therapies for Clostridium difficile Infection
Antibodies, 2014 Clostridium difficile infection has emerged as a growing worldwide health problem. The colitis of Clostridium difficile infection results from the synergistic action of C. difficile secreted toxins A and B upon the colon mucosa.
Michael R. Simon +2 more
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Stressful life events are associated with low secretion rates of immunoglobulin A in saliva in the middle aged and elderly [PDF]
, 2006 Whether chronic stress experience is related to down-regulation of secretory immunoglobulin A (S-IgA) was tested in two substantial cohorts, one middle-aged (N = 640) and one elderly (N = 582), comprising similar numbers of men (N = 556) and women (N ...
Phillips, A.C. +13 more
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The mucosal adjuvant cholera toxin B instructs non-mucosal dendritic cells to promote IgA production via retinoic acid and TGF-β [PDF]
, 2013 It is currently unknown how mucosal adjuvants cause induction of secretory immunoglobulin A (IgA), and how T cell-dependent (TD) or -independent (TI) pathways might be involved.
Boon, Louis +13 more
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Antibodies, 2015 The authors wish to add the following to the acknowledgments of [1]: [...]
Michael R. Simon +2 more
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