Results 261 to 270 of about 465,656 (285)
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Serum IgA Class Anti-IgA Antibody in IgA Nephropathy
Nephron, 1991IgA class anti-IgA antibody was sought by an immunoabsorbent technique in sera from patients with IgA nephropathy (IgA-N, n = 62), other forms of primary glomerulonephritis (PGN, n = 41), seropositive rheumatoid arthritis (RF-positive, n = 18) and normal controls (c, n = 50).
Y, Hiki, M, Saitoh, Y, Kobayashi
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Clinics in Dermatology, 2011
Pemphigus is a life-threatening autoimmune blistering disease. Pemphigus is divided into 4 major types; pemphigus vulgaris, pemphigus foliaceus, paraneoplastic pemphigus, and IgA pemphigus. Among them, IgA pemphigus is characterized by tissue-bound and circulating IgA antibodies targeting desmosomal or nondesmosomal cell surface components in the ...
Daisuke, Tsuruta +11 more
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Pemphigus is a life-threatening autoimmune blistering disease. Pemphigus is divided into 4 major types; pemphigus vulgaris, pemphigus foliaceus, paraneoplastic pemphigus, and IgA pemphigus. Among them, IgA pemphigus is characterized by tissue-bound and circulating IgA antibodies targeting desmosomal or nondesmosomal cell surface components in the ...
Daisuke, Tsuruta +11 more
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Human Pathology, 1977
This presentation attempts to define the criteria for diagnosis of the suggested clinicopathologic entity of IgA nephropathy. Of 250 patients in whom renal biopsies with immunofluorescence, light and electron microscopic, and clinical data were available, 12 patients (4.8 per cent) showed predominance of IgA with localization mainly in the mesangium, a
F, Alexander, A Z, Barabas, R G, Jack
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This presentation attempts to define the criteria for diagnosis of the suggested clinicopathologic entity of IgA nephropathy. Of 250 patients in whom renal biopsies with immunofluorescence, light and electron microscopic, and clinical data were available, 12 patients (4.8 per cent) showed predominance of IgA with localization mainly in the mesangium, a
F, Alexander, A Z, Barabas, R G, Jack
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Trends in Immunology, 2001
IgA has traditionally been regarded a non-inflammatory antibody. This might indeed be true for secretory IgA (SIgA), which exerts its function at mucosal surfaces where commensal microorganisms and dietary antigens prevail. Serum IgA, however, potently triggers (pro)-inflammatory activity upon binding to the myeloid IgA receptor, FcalphaRI.
van Egmond, M. +5 more
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IgA has traditionally been regarded a non-inflammatory antibody. This might indeed be true for secretory IgA (SIgA), which exerts its function at mucosal surfaces where commensal microorganisms and dietary antigens prevail. Serum IgA, however, potently triggers (pro)-inflammatory activity upon binding to the myeloid IgA receptor, FcalphaRI.
van Egmond, M. +5 more
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Current Opinion in Pediatrics, 1999
Immunoglobulin A nephropathy results from the abnormal deposition of IgA immunoglobulin in the glomerulus, which leads to the characteristic presentation of painless hematuria. It is the most common glomerulonephritis worldwide. Originally described 30 years ago, it was thought to follow a benign course.
T E, Hunley, V, Kon
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Immunoglobulin A nephropathy results from the abnormal deposition of IgA immunoglobulin in the glomerulus, which leads to the characteristic presentation of painless hematuria. It is the most common glomerulonephritis worldwide. Originally described 30 years ago, it was thought to follow a benign course.
T E, Hunley, V, Kon
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Anti-IgA antibodies in IgA-deficient children
Journal of Clinical Immunology, 1988IgG and IgM isotype antibodies to polyclonal human IgA, myeloma IgA1, and myeloma IgA2 were estimated in 38 IgA-deficient children aged between 0.9 and 15 years. All children had IgM anti-IgA antibodies. IgG antibodies against either polyclonal IgA, IgA1, or IgA2 were present in 63% of the IgA-deficient children.
F H, Sennhauser +5 more
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Role of IgA in IgA nephropathy
The Journal of Pediatrics, 1990IgA nephropathy (Berger disease) is defined by the dominant or codominant deposition of IgA in the renal mesangium. There is much evidence in vitro to suggest up-regulation of the IgA immune response in patients. Data from tonsillar and bone marrow-derived lymphocytes and from in vivo immunization studies indicate that the primary defect is an up ...
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Physiology of IgA and IgA Deficiency
Journal of Clinical Immunology, 2001Although secretory immunoglobulin A (IgA) is important in mucosal immunity. selective IgA deficiency is the most common primary immunodeficiency of humans. In most cases this defect is not associated with any illness. The reasons for this are unknown, but other immunological compensations might provide sufficient or complete restitution. Alternatively,
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