Results 1 to 10 of about 285,914 (256)

Geochemical indicators of paleo-seismicity based on the data of study of Fumarolnoe lake bottom sediments (Kamchatka, Uzon) [PDF]

E3S Web of Conferences, 2019
The distribution of chemical elements in bottom sediments of Fumarolnoe lake was obtained by XRFA. The mineral composition of the sediment was examined by SEM, XPA.
Kirichenko Ivan, Dobretsov Nikolay, Zhmodik Sergey, Lazareva Elena, Belyanin Dmitry   +4 more
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A study on serodiagnosis of scrub typhus in a Teaching Hospital of South India [PDF]

Perspectives In Medical Research, 2021
Background: crub typhus is caused by Orientia tsutsugamushi (rickettsial disease) commonly transmitted by the bite of larval chiggers of trombiculid mites. It has been one of the important causes of febrile illness, especially in south India.
Santosha Kelamane 1 , Cheruku Pranuthi Mispah 2 , K. Sri Sandhya1
doaj   +1 more source

A novel ruthenium complex with 5-fluorouracil suppresses colorectal cancer stem cells by inhibiting Akt/mTOR signaling

Cell Death Discovery, 2023
[Ru(5-FU)(PPh3)2(bipy)]PF6 (Ru/5-FU) is a novel ruthenium complex with 5-fluorouracil with promising potential against colorectal cancer (CRC). In the present study, we investigated the molecular mechanism of Ru/5-FU action in HCT116 CRC cells.
Valdenizia R. Silva, Luciano de S. Santos, Maria V. L. de Castro, Rosane B. Dias, Ludmila de F. Valverde, Clarissa A. G. Rocha, Milena B. P. Soares, Claudio A. Quadros, Rodrigo S. Correa, Alzir A. Batista, Daniel P. Bezerra   +10 more
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Genome-wide Translational Changes Induced by the Prion [PSI+]

Cell Reports, 2014
Prions are infectious proteins that can adopt a structural conformation that is then propagated among other molecules of the same protein. [PSI+] is an aggregated conformation of the translational release factor eRF3.
Agnès Baudin-Baillieu, Rachel Legendre, Claire Kuchly, Isabelle Hatin, Stéphane Demais, Claire Mestdagh, Daniel Gautheret, Olivier Namy   +7 more
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Hydroxyurea Scavenges Free Radicals and Induces the Expression of Antioxidant Genes in Human Cell Cultures Treated With Hemin

Frontiers in Immunology, 2020
The excessive release of heme during hemolysis contributes to the severity of sickle cell anemia (SCA) by exacerbating hemoglobin S (HbS) autoxidation, inflammation and systemic tissue damage. The present study investigated the effect of hydroxyurea (HU)
Sânzio Silva Santana, Sânzio Silva Santana, Thassila Nogueira Pitanga, Thassila Nogueira Pitanga, Jeanne Machado de Santana, Dalila Lucíola Zanette, Jamile de Jesus Vieira, Sètondji Cocou Modeste Alexandre Yahouédéhou, Corynne Stéphanie Ahouefa Adanho, Sayonara de Melo Viana, Nivea Farias Luz, Valeria Matos Borges, Marilda Souza Goncalves, Marilda Souza Goncalves   +13 more
doaj   +1 more source

New ruthenium-xanthoxylin complex eliminates colorectal cancer stem cells by targeting the heat shock protein 90 chaperone

Cell Death and Disease, 2023
In this work, we describe a novel ruthenium-xanthoxylin complex, [Ru(phen)2(xant)](PF6) (RXC), that can eliminate colorectal cancer (CRC) stem cells by targeting the chaperone Hsp90.
Luciano de S. Santos, Valdenizia R. Silva, Maria V. L. de Castro, Rosane B. Dias, Ludmila de F. Valverde, Clarissa A. G. Rocha, Milena B. P. Soares, Claudio A. Quadros, Edjane R. dos Santos, Regina M. M. Oliveira, Rose M. Carlos, Paulo C. L. Nogueira, Daniel P. Bezerra   +12 more
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Structure, Function, and Therapeutic Use of IgM Antibodies

Antibodies, 2020
Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution. IgMs are initially expressed during B cell ontogeny and are the first antibodies secreted following exposure to ...
Bruce A. Keyt, Ramesh Baliga, Angus M. Sinclair, Stephen F. Carroll, Marvin S. Peterson   +4 more
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Kinetics of IgM, IgA, IgG to SARS-CoV-2 in children with COVID-19 in Lviv region in different periods of the infectious process depending on the severity of the course and age

Acta Medica Leopoliensia, 2023
Aim. The research aims at analyzing the kinetics of IgA, IgM, and IgG to SARS-CoV-2 in children based on the severity of COVID-19 and age. Materials and Methods.
Maria Stasiv
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Detection of IgG and IgM Levels in Patients with COVID-19 in Mosul Province, Iraq

Journal of Pure and Applied Microbiology, 2022
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) has become the most dangerous viral infection worldwide. Since its identification in late 2019, the number of medical trials to combat the infection has sharply increased.
Hasan Faisal Hussein Kahya, Mohammed Taha Mahmood   +1 more
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Evaluation of serum immunoglobulin (IgG, IgM, IgA) in oral cancer patients – A case control study

Journal of Indian Academy of Oral Medicine and Radiology, 2021
Background: Very few studies have been done to evaluate the level of serum immunoglobulins (IgG, IgM, and IgA) in patients with oral cancer as tumor markers. Aims and Objectives: The aim of this study was to estimate the serum immunoglobulins level (IgG,
Vivek M Tarsariya, Nilesh Raval, Dhaval N Mehta, Mukesh K Asrani, Vijay K Asrani, Kaushik S Barot   +5 more
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