Results 1 to 10 of about 264,380 (213)
Ontogeny of IgM and IgM-bearing cells in rainbow trout
Developmental and Comparative Immunology, 1993 We have studied the ontogenic development of immunoglobulin M (IgM) and of IgM-bearing cells in the rainbow trout, Oncorhynchus mykiss. Lymphocytes showing cytoplasmic IgM were first observed in embryos at 12 days before hatch (14 degrees C). At this stage, no cells positive for surface IgM were present. Lymphocytes bearing surface IgM were observed at
J Dominguez +2 more
exaly +6 more sources
Geochemical indicators of paleo-seismicity based on the data of study of Fumarolnoe lake bottom sediments (Kamchatka, Uzon) [PDF]
E3S Web of Conferences, 2019 The distribution of chemical elements in bottom sediments of Fumarolnoe lake was obtained by XRFA. The mineral composition of the sediment was examined by SEM, XPA.
Kirichenko Ivan +4 more
doaj +1 more source
A study on serodiagnosis of scrub typhus in a Teaching Hospital of South India [PDF]
Perspectives In Medical Research, 2021 Background: crub typhus is caused by Orientia tsutsugamushi (rickettsial disease) commonly transmitted by the bite of larval chiggers of trombiculid mites. It has been one of the important causes of febrile illness, especially in south India.
Santosha Kelamane 1 , Cheruku Pranuthi Mispah 2 , K. Sri Sandhya1
doaj +1 more source
Cell Death Discovery, 2023 [Ru(5-FU)(PPh3)2(bipy)]PF6 (Ru/5-FU) is a novel ruthenium complex with 5-fluorouracil with promising potential against colorectal cancer (CRC). In the present study, we investigated the molecular mechanism of Ru/5-FU action in HCT116 CRC cells.
Valdenizia R. Silva +10 more
doaj +1 more source
Genome-wide Translational Changes Induced by the Prion [PSI+]
Cell Reports, 2014 Prions are infectious proteins that can adopt a structural conformation that is then propagated among other molecules of the same protein. [PSI+] is an aggregated conformation of the translational release factor eRF3.
Agnès Baudin-Baillieu +7 more
doaj +1 more source
Cell Death and Disease, 2023 In this work, we describe a novel ruthenium-xanthoxylin complex, [Ru(phen)2(xant)](PF6) (RXC), that can eliminate colorectal cancer (CRC) stem cells by targeting the chaperone Hsp90.
Luciano de S. Santos +12 more
doaj +1 more source
Clinical Significance of 7s IgM in Monoclonal IgM Diseases [PDF]
BMJ, 1971 The sera from 117 patients with diseases associated with a high production of monoclonal IgM were analysed for the presence of low molecular weight (7s) IgM by using a simple thin-layer Sephadex technique. 7s IgM was found in the sera of patients with myelomata (66%), lymphomata (45%), and Waldenström's macroglobulinaemia (20%), but was absent from the
P M, Carter, J R, Hobbs
openaire +2 more sources
IgM, Not 7S-IgM, as Cause of Increased Serum IgM Concentrations in Goiter Patients
Experimental Biology and Medicine, 1972 Circulating concentrations of immunoglobulin-M (IgM) are increased in about half of patients with endemic or sporadic nontoxic goiter (1). In the single radial immunodiffusion technique used to test those serums (2), the diameter of the precipitin ring developed against the anti-IgM serum in the agar is proportional to the logarithm of the amount of ...
I, Radichevich, J, Morse, S C, Werner
openaire +2 more sources
Frontiers in Immunology, 2020 The excessive release of heme during hemolysis contributes to the severity of sickle cell anemia (SCA) by exacerbating hemoglobin S (HbS) autoxidation, inflammation and systemic tissue damage. The present study investigated the effect of hydroxyurea (HU)
Sânzio Silva Santana +13 more
doaj +1 more source
Emerging drugs targeting cellular redox homeostasis to eliminate acute myeloid leukemia stem cells
Redox Biology, 2023 Acute myeloid leukemia (AML) is a very heterogeneous group of disorders with large differences in the percentage of immature blasts that presently are classified according to the specific mutations that trigger malignant proliferation among thousands of ...
Rafaela G.A. Costa +6 more
doaj +1 more source