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Ruthenium Complexes Containing Heterocyclic Thioamidates Trigger Caspase-Mediated Apoptosis Through MAPK Signaling in Human Hepatocellular Carcinoma Cells

open access: yesFrontiers in Oncology, 2019
Herein, ruthenium complexes containing heterocyclic thioamidates [Ru(mmi)(bipy)(dppb)]PF6 (1), [Ru(tzdt)(bipy)(dppb)]PF6 (2), [Ru(dmp)(bipy)(dppb)]PF6 (3) and [Ru(mpca)(bipy)(dppb)]PF6 (4) were investigated for their cellular and molecular effects in ...
Sara P. Neves   +10 more
doaj   +1 more source

Serum immunoglobulin levels in male schizophrenic patients before and after olanzapine therapy [PDF]

open access: yesالمجلة العراقية للصيدلة, 2011
Objective: To evaluate the effect of olanzapine therapy on serum immunoglobulin levels (IgA, IgG, IgM) in male schizophrenic patients after 2 months of treatment by olanzapine at a daily dose of 20 mg.
Mahmoud Khudhayer Oglah Hussein
doaj   +1 more source

An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV

open access: yesEmerging Microbes and Infections, 2023
The capacity of SARS-CoV-2 to evolve poses challenges to conventional prevention and treatment options such as vaccination and monoclonal antibodies, as they rely on viral receptor binding domain (RBD) sequences from previous strains.
Hailong Guo   +27 more
doaj   +1 more source

Sex specific regulation of TSPY-Like 2 in the DNA damage response of cancer cells

open access: yesCell Death and Disease, 2023
Females have a lower probability to develop somatic cancers and a better response to chemotherapy than males. However, the reasons for these differences are still not well understood.
Miriana Cardano   +6 more
doaj   +1 more source

Ethical Work Climate Untuk Menciptakan Moral Awareness Karyawan Pada Koperasi Bank Perkreditan Rakyat Tribakti Nganjuk

open access: yesJurnal Manajemen Teori dan Terapan, 2016
This study would examined empirically which one of these ethical criteria, namely self-interest, company, interest, efficiency, friendship, team play, social responsibility, personal morality, rules and procedures, and the law or professional code ...
Siti Sulasmi, IGM Dwi Widhianto
doaj   +1 more source

PLEIOTROPIC EFFECT OF POLYMORPHISMS IN THE BCL11A GENE IN INDIVIDUALS WITH SICKLE CELL ANEMIA

open access: yesHematology, Transfusion and Cell Therapy, 2023
Sickle cell anemia (SCA) is one of the types of sickle cell disease (SCD), which is characterized by hematological events such as hemolysis and endothelial damage that culminate in vaso-occlusion, leading to the appearance of several clinical ...
AMJ Oliveira   +8 more
doaj   +1 more source

Lipids: Evergreen autofluorescent biomarkers for the liver functional profiling

open access: yesEuropean Journal of Histochemistry, 2017
Depending on their chemical nature, lipids can be classified in two main categories: hydrophilic, greatly contributing to membrane composition and subcellular organelle compartmentalization, and hydrophobic, mostly triglycerides, greatly enrolled in the ...
Anna Cleta Croce, Giovanni Bottiroli
doaj   +1 more source

ESTUDO INTEGRADO DA HEPATITE E EM SALVADOR-BA

open access: yesBrazilian Journal of Infectious Diseases, 2022
Introdução/Objetivo: A hepatite E é uma doença negligenciada no Brasil. O HEV pode ser transmitido pela via fecal-oral, sanguínea e zoonótica a partir principalmente de suínos, e pode ocasionar doença crônica em pacientes imunocomprometidos.
Daniela Santana Mendes   +19 more
doaj   +1 more source

Toxoplasma gondii Recombinant antigen AMA1: Diagnostic Utility of Protein Fragments for the Detection of IgG and IgM Antibodies

open access: yesPathogens, 2020
Toxoplasma gondii is an important zoonotic protozoan that infects a wide variety of vertebrates as intermediate hosts. For this reason, the diagnosis of this disease is very important and requires continuous improvement.
Bartłomiej Ferra   +4 more
doaj   +1 more source

Emetine induces oxidative stress, cell differentiation and NF-κB inhibition, suppressing AML stem/progenitor cells

open access: yesCell Death Discovery
Acute myeloid leukemia (AML) is a fatal malignancy of the blood and bone marrow. Leukemic stem cells (LSCs) are a rare subset of leukemic cells that promote the development and progression of AML, and eradication of LSCs is critical for effective control
Suellen L. R. Silva   +12 more
doaj   +1 more source

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