Results 41 to 50 of about 235,216 (254)

Sex specific regulation of TSPY-Like 2 in the DNA damage response of cancer cells

Cell Death and Disease, 2023
Females have a lower probability to develop somatic cancers and a better response to chemotherapy than males. However, the reasons for these differences are still not well understood.
Miriana Cardano, Martina Magni, Roberta Alfieri, Siu Yuen Chan, Simone Sabbioneda, Giacomo Buscemi, Laura Zannini   +6 more
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]

, 2013
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad, B. Tolani, Ballon, Benhamou, Bower, Bren, C. Graham, Chang, Chaudhary, Chugh, Delmore, Dong, Du, Dupin, Dupin, Eeva, Eeva, Field, Gerondakis, Guasparri, H. Matta, H. Yi, Hassman, Herzog, Lee, Liu, Madureira, Matta, Matta, Matta, Matta, Mineva, Nador, Niiro, P. M. Chaudhary, Parravicini, Punj, Schauer, Soulier, Sun, Sun, Sun, Thome, Vrzalikova, Waterston, Wu, Wu, Wu, Y. Suo, Y. Yang, Yang, Yang, Young, Zhao   +53 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

PLEIOTROPIC EFFECT OF POLYMORPHISMS IN THE BCL11A GENE IN INDIVIDUALS WITH SICKLE CELL ANEMIA

Hematology, Transfusion and Cell Therapy, 2023
Sickle cell anemia (SCA) is one of the types of sickle cell disease (SCD), which is characterized by hematological events such as hemolysis and endothelial damage that culminate in vaso-occlusion, leading to the appearance of several clinical ...
AMJ Oliveira, LM Fiuza, CVB Figueiredo, CC Guarda, RP Santiago, SCMA Yahouédéhou, SP Carvalho, IM Lyra, MS Goncalves   +8 more
doaj   +1 more source

Intermittence of the Map of Kinetic Sunyaev-Zel'dovich Effect and Turbulence of IGM

, 2011
We investigate the possibility of detecting the turbulent state of the IGM with the kinetic Sunyaev-Zel'dovich (kSZ) effect. Being sensitive to the divergence-free component of the momentum field of the IGM, the kSZ effect might be used to probe the ...
Atrio-Barandela, Atrio-Barandela, Cao, Feng, Frisch, Gnedin, Komatsu, Liu, Lu, Pando, Springel, Sunyaev, Zhang, Zhu, Zhu   +14 more
core   +1 more source

A new model framework for circumgalactic Ly$\alpha$ radiative transfer constrained by galaxy-Ly$\alpha$ forest clustering [PDF]

, 2018
We present a new perturbative approach to "constrained Ly$\alpha$ radiative transfer'" (RT) through the circum- and inter-galactic medium (CGM and IGM). We constrain the HI content and kinematics of the CGM and IGM in a physically motivated model, using ...
Dijkstra, Mark, Kakiichi, Koki
core   +2 more sources

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Ethical Work Climate Untuk Menciptakan Moral Awareness Karyawan Pada Koperasi Bank Perkreditan Rakyat Tribakti Nganjuk

Jurnal Manajemen Teori dan Terapan, 2016
This study would examined empirically which one of these ethical criteria, namely self-interest, company, interest, efficiency, friendship, team play, social responsibility, personal morality, rules and procedures, and the law or professional code ...
Siti Sulasmi, IGM Dwi Widhianto
doaj   +1 more source

ESTUDO INTEGRADO DA HEPATITE E EM SALVADOR-BA

Brazilian Journal of Infectious Diseases, 2022
Introdução/Objetivo: A hepatite E é uma doença negligenciada no Brasil. O HEV pode ser transmitido pela via fecal-oral, sanguínea e zoonótica a partir principalmente de suínos, e pode ocasionar doença crônica em pacientes imunocomprometidos.
Daniela Santana Mendes, Luan Henrique Paim Santos, Luíza Araújo de Santana Cavalcanti, Victoria Cruz Paraná, Júlia Stifelman Freire Alves, André Costa Lyra, Mariana Pamponet Motta, Maria Isabel Schinoni, Nelma Pereira Santana, Carlos Roberto Brites Alves, Alessandro de Moura Almeida, Paulo Benigno Pena Batista, Jorge Raimundo Lins Ribas, Maria Tereza Vagas Leal Mascarenhas, Maria Alice Sant'Anna Zarife, Ricardo David Couto, Sidelcina Rugieri Pacheco, Raymundo Paraná Ferreira Filho, Mitermayer Galvão dos Reis, Luciano Kalabric Silva   +19 more
doaj   +1 more source

Vorticity of IGM Velocity Field on Large Scales

, 2010
We investigate the vorticity of the IGM velocity field on large scales with cosmological hydrodynamic simulation of the concordance model of LCDM. We show that the vorticity field is significantly increasing with time as it can effectively be generated ...
Bahcall, Batchelor, Binney, Bonazzola, Cassano, Davis, Del Zanna, Feng, He, Kolmogorov, Komatsu, Landau, Li-Zhi Fang, Liu, Liu, Long-long Feng, Lu, Mac Low, Nagai, Pichon, Schmidt, Shu, Shull, Weishan Zhu, Yang, Zhang, Zheng   +26 more
core   +1 more source