Results 41 to 50 of about 285,914 (256)

ESTUDO INTEGRADO DA HEPATITE E EM SALVADOR-BA

Brazilian Journal of Infectious Diseases, 2022
Introdução/Objetivo: A hepatite E é uma doença negligenciada no Brasil. O HEV pode ser transmitido pela via fecal-oral, sanguínea e zoonótica a partir principalmente de suínos, e pode ocasionar doença crônica em pacientes imunocomprometidos.
Daniela Santana Mendes, Luan Henrique Paim Santos, Luíza Araújo de Santana Cavalcanti, Victoria Cruz Paraná, Júlia Stifelman Freire Alves, André Costa Lyra, Mariana Pamponet Motta, Maria Isabel Schinoni, Nelma Pereira Santana, Carlos Roberto Brites Alves, Alessandro de Moura Almeida, Paulo Benigno Pena Batista, Jorge Raimundo Lins Ribas, Maria Tereza Vagas Leal Mascarenhas, Maria Alice Sant'Anna Zarife, Ricardo David Couto, Sidelcina Rugieri Pacheco, Raymundo Paraná Ferreira Filho, Mitermayer Galvão dos Reis, Luciano Kalabric Silva   +19 more
doaj   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Effect of LUX and IB on anti-IgM-induced activation of BCR signaling in JeKo-1 and RL cells.

, 2023
Cells were pre-treated for 2 h with either LUX or IB and then stimulated with anti-human IgM or left unstimulated. Whole cell lysates were analyzed by Western blotting for the indicated phosphoproteins in (A) JeKo-1 and (B) RL cells. Representative blots
Stephen B. Howell (424989), Himangshu Sonowal (14761882), William G. Rice (2065555)   +2 more
core   +1 more source

Emetine induces oxidative stress, cell differentiation and NF-κB inhibition, suppressing AML stem/progenitor cells

Cell Death Discovery
Acute myeloid leukemia (AML) is a fatal malignancy of the blood and bone marrow. Leukemic stem cells (LSCs) are a rare subset of leukemic cells that promote the development and progression of AML, and eradication of LSCs is critical for effective control
Suellen L. R. Silva, Ingrid R. S. B. Dias, Ana Carolina B. da C. Rodrigues, Rafaela G. A. Costa, Maiara de S. Oliveira, Gabriela A. da C. Barbosa, Milena B. P. Soares, Rosane B. Dias, Ludmila F. Valverde, Clarissa A. G. Rocha, Nainita Roy, Christopher Y. Park, Daniel P. Bezerra   +12 more
doaj   +1 more source

Consequences of internalization and phagocytosis of Listeria during an infectious process

Бюллетень сибирской медицины, 2003
In the article there have been discussed the consequences of Listeria internalization and phagocytosis depending on hepatocyte and macrophage receptors type (Met, gC1q-R, C3b-R, Fc-R).
Yu. N. Odintsov, V. M. Perelmuter
doaj   +1 more source

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

Arthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

Piplartine eliminates CD34 + AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling

Cell Death Discovery
Acute myeloid leukaemia (AML) is a haematological malignancy characterised by the accumulation of transformed myeloid progenitors in the bone marrow. Piplartine (PL), also known as piperlongumine, is a pro-oxidant small molecule extracted from peppers ...
Ana Carolina B. da C. Rodrigues, Suellen L. R. Silva, Ingrid R. S. B. Dias, Rafaela G. A. Costa, Maiara de S. Oliveira, Milena B. P. Soares, Rosane B. Dias, Ludmila F. Valverde, Clarissa A. G. Rocha, Emily M. Johnson, Cristina Pina, Daniel P. Bezerra   +11 more
doaj   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution

, 2017
Three different receptors that interact with the constant domains of IgM have been identified: the polymeric immunoglobulin (Ig) receptor (PIGR), the dual receptor for IgA/IgM (Fc alpha mu R) and the IgM receptor (Fc mu R).
Akula, Srinivas,, Lars Hellman, Hellman, Lars,, Srinivas Akula   +3 more
core   +1 more source

Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis

Cell Death Discovery
Acute myeloid leukaemia (AML) is a lethal bone marrow neoplasm caused by genetic alterations in blood cell progenitors. Leukaemic stem cells (LSCs) are responsible for the development of AML, drug resistance and relapse.
Ingrid R. S. B. Dias, Rafaela G. A. Costa, Ana Carolina B. da C. Rodrigues, Suellen L. R. Silva, Maiara de S. Oliveira, Milena B. P. Soares, Rosane B. Dias, Ludmila F. Valverde, Clarissa A. Gurgel Rocha, Lauren V. Cairns, Ken I. Mills, Daniel P. Bezerra   +11 more
doaj   +1 more source