Results 61 to 70 of about 235,216 (254)

Lipids: Evergreen autofluorescent biomarkers for the liver functional profiling

open access: yesEuropean Journal of Histochemistry, 2017
Depending on their chemical nature, lipids can be classified in two main categories: hydrophilic, greatly contributing to membrane composition and subcellular organelle compartmentalization, and hydrophobic, mostly triglycerides, greatly enrolled in the ...
Anna Cleta Croce, Giovanni Bottiroli
doaj   +1 more source

Effect of Intergalactic Medium on the Observability of Lyman Alpha Emitters during Cosmic Reionization

open access: yes, 2012
We perform a systematic study of how the inhomogeneities in the Inter-Galactic Medium (IGM) affect the observability of Lyman Alpha Emitters (LAEs) around the Epoch of Reionization.
Adams   +124 more
core   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli   +10 more
wiley   +1 more source

Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis

open access: yesCell Death Discovery
Acute myeloid leukaemia (AML) is a lethal bone marrow neoplasm caused by genetic alterations in blood cell progenitors. Leukaemic stem cells (LSCs) are responsible for the development of AML, drug resistance and relapse.
Ingrid R. S. B. Dias   +11 more
doaj   +1 more source

Evaluation of bio-conjugation methods for obtaining of synthetic positive control for IgM-capture ELISA

open access: yesRegulatory Mechanisms in Biosystems, 2014
The enzyme-linked immunosorbent assay (ELISA) is the most informative and versatile method of serological diagnostics. The possibility of detecting by ELISA specific antibodies of different classes allow to differentiate primary infectious process and ...
O. Y. Galkin, Y. V. Gorshunov
doaj   +1 more source

The Ionizing Efficiency of the First Stars [PDF]

open access: yes, 2003
We investigate whether a single population of first stars could have influenced both the metal enrichment and reionization of the high-redshift intergalactic medium (IGM), by calculating the generated ionizing radiation per unit metal yield as a function
Truran, James W., Venkatesan, Aparna
core   +3 more sources

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

open access: yesArthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni   +7 more
wiley   +1 more source

Piplartine eliminates CD34 + AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling

open access: yesCell Death Discovery
Acute myeloid leukaemia (AML) is a haematological malignancy characterised by the accumulation of transformed myeloid progenitors in the bone marrow. Piplartine (PL), also known as piperlongumine, is a pro-oxidant small molecule extracted from peppers ...
Ana Carolina B. da C. Rodrigues   +11 more
doaj   +1 more source

Consequences of internalization and phagocytosis of Listeria during an infectious process

open access: yesБюллетень сибирской медицины, 2003
In the article there have been discussed the consequences of Listeria internalization and phagocytosis depending on hepatocyte and macrophage receptors type (Met, gC1q-R, C3b-R, Fc-R).
Yu. N. Odintsov, V. M. Perelmuter
doaj   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin   +14 more
wiley   +1 more source

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