Results 71 to 80 of about 285,914 (256)

Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model

Frontiers in Oncology, 2019
Ruthenium complexes with piplartine, [Ru(piplartine)(dppf)(bipy)](PF6)2 (1) and [Ru(piplartine)(dppb)(bipy)](PF6)2 (2) (dppf = 1,1-bis(diphenylphosphino) ferrocene; dppb = 1,4-bis(diphenylphosphino)butane and bipy = 2,2′-bipyridine), were recently ...
Ingrid R. S. Baliza, Suellen L. R. Silva, Luciano de S. Santos, João H. Araujo Neto, Rosane B. Dias, Caroline B. S. Sales, Clarissa A. Gurgel Rocha, Milena B. P. Soares, Alzir A. Batista, Daniel P. Bezerra   +9 more
doaj   +1 more source

Biosynthesis of Spatially Differentiated Cellulose for Flexible All‐in‐one Supercapacitors

Advanced Science, EarlyView.
Spatially differentiated bacterial cellulose is grown by oxygen‐guided biosynthesis to form dense surface regions connected by an open fibrillar interlayer. This architecture supports electroactive material loading, ion transport, and mechanical stability in an all‐in‐one supercapacitor, showing how biological assembly can create device‐ready ...
Xin Shu, Yi Lu, Xuetong Shi, Zhangmin Wan, Peijin Jiang, Minke Yang, Qingshi Tu, Orlando J. Rojas   +7 more
wiley   +1 more source

Can Tenebrio molitor oil replace palm fatty acid distillate and soybean oil in the diet of lactating sheep? Effects on in vitro ruminal fermentation and biohydrogenation

Italian Journal of Animal Science
Insect-derived lipids are gaining attention as sustainable alternatives to conventional fat sources in animal feeding due to environmental and market concerns. Expanding research on insect oils inclusion in ruminant diets, currently limited, is necessary
C. Baila, M. Hassanien, G. Fondevila, E. Barrio, P. G. Toral, P. Frutos, G. Hervás   +6 more
doaj   +1 more source

Lipids: Evergreen autofluorescent biomarkers for the liver functional profiling

European Journal of Histochemistry, 2017
Depending on their chemical nature, lipids can be classified in two main categories: hydrophilic, greatly contributing to membrane composition and subcellular organelle compartmentalization, and hydrophobic, mostly triglycerides, greatly enrolled in the ...
Anna Cleta Croce, Giovanni Bottiroli
doaj   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

P815: HIGH VALENCY OF IGM-2644, A CD38XCD3 IGM BISPECIFIC T CELL ENGAGER, DISPLACES DARATUMUMAB BINDING AND INDUCES POTENT MULTIPLE MYELOMA CELL KILLING

HemaSphere, 2023
Kevin C. Hart, Daniel Santos, Deepal Pandya, Rong Deng, Keyu LI, Yinghui Guan, Genevive Hernandez, Thomas Manley, Maya K. Leabman, Paul R. Hinton, Liqin Liu, Angus M. Sinclair, Albert F. Candia, Stephen F. Carroll, Bruce A. Keyt, Maya F. Kotturi   +15 more
doaj   +1 more source

EARLY DETECTION AND EPIDEMIOLOGICAL PROFILE OF OROPOUCHE FEVER IN SALVADOR-BA

Brazilian Journal of Infectious Diseases
Introduction/Objectives: Oropouche fever, caused by the Oropouche virus (OROV), is an arboviral disease with sylvatic and urban cycles endemic to the Amazon region. Transmission occurs through the biting midge Culicoides paraensis. Symptoms include fever,
Adryele Figueiredo Pinheiro, Fernanda Lopes Habib, Marcos Silva Brito, Davi Bastos Lemos, Maria Paula Sampaio, Natalie Nascimento Oliveira, Joilson de Gusmao Guimaraes, Ively Paixão Santos, Gubio Soares Campos, Isadora Cristina de Siqueira   +9 more
doaj   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli

Advanced Science, EarlyView.
Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma, Yuxin Zhang, Lujia Sun, Hong Jiang, Fan Li, Wenming Liu, Shenao Zhou, Mengting Wang, Weijian Huang, Xu Zhou, Caiyang Chen, Qiuqiu Zhang, Xiaoyan Jin, Feihan Yan, Hongping Wu, Yonghong Yin, Xinling Wang, Hexin Yan, Weifeng Yu   +18 more
wiley   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

Advanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan, Soham Maity, Herbert Kavunja, Yuvarani Murali, Ting‐An Chen, Chang‐xin Huo, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source