Results 71 to 80 of about 235,216 (254)

L’adozione del nuovo sistema di riferimento geodetico Italiano

GEOmedia, 2012
Sulla Gazzetta Ufficiale n. 48 del 27 febbraio 2012 (supplemento ordinario n. 37) è stato pubblicato il DM con cui è stato adottato un nuovo sistema di riferimento denominato ETRF2000 (2008.0). I precedenti sistemi di riferimento, ancora in uso in Italia,
Renzo Carlucci, Renzo Maseroli, Giovanni Petrosino   +2 more
doaj  

Ru(II)-based complexes containing 2-thiouracil derivatives suppress liver cancer stem cells by targeting NF-κB and Akt/mTOR signaling

Cell Death Discovery
Cancer stem cells (CSCs) are defined as a rare population of cancer cells related to tumor initiation and maintenance. These cells are primarily responsible for tumor growth, invasion, metastasis, recurrence, and resistance to chemotherapy. In this paper,
Larissa M. Bomfim, Sara P. Neves, Amanda M. R. M. Coelho, Mateus L. Nogueira, Rosane B. Dias, Ludmila de F. Valverde, Clarissa A. G. Rocha, Milena B. P. Soares, Alzir A. Batista, Rodrigo S. Correa, Daniel P. Bezerra   +10 more
doaj   +1 more source

Do we need broad immunological work-up in all patients with CIS? [PDF]

, 2012
BACKGROUND: The aim of this study was to determine the prevalence of altered immunological tests and their clinical significance in patients with clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS). ----- PATIENTS AND METHODS:
Adamec, Ivan, Bošković, Mateja, Gabelić, Tereza, Habek, Mario, Posavec, Vanja, Radmilović, Marin, Škvorc, Ana   +6 more
core   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

ZIBA MIR-HOSSEINI THOUGHTS : GENDER AND PUNISHMENT FOR ADULTERY IN ISLAM

International Journal of Islamic Education, Research and Multiculturalism
Ziba Mir-Hosseini is a Muslim feminist fighter, he examines how misogynistic verses often exclude women. So far, women are considered inferior to men as superior, especially when it comes to imposing sanctions for adulterers, women are more likely to ...
Nova Yanti Maleha, Waldi Nopriansyah, Dwi Noviani   +2 more
doaj   +1 more source

Cosmic Ray production of Beryllium and Boron at high redshift

, 2007
Recently, new observations of Li6 in Pop II stars of the galactic halo have shown a surprisingly high abundance of this isotope, about a thousand times higher than its predicted primordial value.
Berezhko E. G., Cayrel R., David Maurin, Elisabeth Vangioni, Emmanuel Rollinde, Keith A. Olive, Meneguzzi M., Nissen P. E., Primas F., Primas F., Primas F., Spite F., Susumu Inoue   +12 more
core   +3 more sources

IgM Myeloma: An IgM Gammopathy Distinct from Waldenstrom's Macroglobulinemia [PDF]

Hematology, 2001
A 65-year-old patient with an IgM gammopathy, plasma cell infiltration of the bone marrow, lytic lesions of the skeleton, and symptoms of hyperviscosity was evaluated. A diagnosis of IgM myeloma was made. Treatment for multiple myeloma was initiated and resulted in a significant clinical response. There is ongoing debate whether IgM myeloma exists as a
L T, Nordquist, H I, Saba, L C, Moscinski   +2 more
openaire   +2 more sources

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source

Hedgehog components are overexpressed in a series of liver cancer cases

Scientific Reports
Liver cancers, including hepatocellular carcinoma (HCC), are the sixth most common cancer and the third leading cause of cancer-related death worldwide, representing a global public health problem. This study evaluated nine patients with HCC.
Caroline Brandi Schlaepfer Sales, Rosane Borges Dias, Ludmila de Faro Valverde, Larissa M. Bomfim, Lais Almeida Silva, Nanashara C. de Carvalho, Jorge Luiz Andrade Bastos, Tatiana Martins Tilli, Gisele Vieira Rocha, Milena Botelho Pereira Soares, Luiz Antonio Rodrigues de Freitas, Clarissa A. Gurgel Rocha, Daniel P. Bezerra   +12 more
doaj   +1 more source