Results 21 to 30 of about 215,830 (266)

Structure, Function, and Therapeutic Use of IgM Antibodies

open access: yesAntibodies, 2020
Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution. IgMs are initially expressed during B cell ontogeny and are the first antibodies secreted following exposure to ...
Bruce A. Keyt   +4 more
doaj   +1 more source

Kinetics of IgM, IgA, IgG to SARS-CoV-2 in children with COVID-19 in Lviv region in different periods of the infectious process depending on the severity of the course and age

open access: yesActa Medica Leopoliensia, 2023
Aim. The research aims at analyzing the kinetics of IgA, IgM, and IgG to SARS-CoV-2 in children based on the severity of COVID-19 and age. Materials and Methods.
Maria Stasiv
doaj   +1 more source

Detection of IgG and IgM Levels in Patients with COVID-19 in Mosul Province, Iraq

open access: yesJournal of Pure and Applied Microbiology, 2022
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) has become the most dangerous viral infection worldwide. Since its identification in late 2019, the number of medical trials to combat the infection has sharply increased.
Hasan Faisal Hussein Kahya   +1 more
doaj   +1 more source

Mechanism of IgM Polymerization [PDF]

open access: yesProceedings of the National Academy of Sciences, 1974
The stoichiometry of J chain in pentamer IgM has been determined by measuring the radiolabeled thiols in the constituent chains after complete reduction and alkylation of the polymer. One mole of J was found to be disulfide bonded to 1 mol of pentamer.
R M, Chapuis, M E, Koshland
openaire   +2 more sources

IgM’s exit route [PDF]

open access: yesJournal of Experimental Medicine, 2018
In this issue of JEM, Thierry et al. (https://doi.org/10.1084/jem.20180344) demonstrate that, once secreted by freshly activated plasmablasts, IgM leaves the lymph node via the microarchitecture of the fibroblastic reticular cell conduit. This work demonstrates how the very peculiar stromal compartment of lymphatic organs optimizes the systemic ...
Anne Reversat, Michael Sixt
openaire   +2 more sources

Evaluation of serum immunoglobulin (IgG, IgM, IgA) in oral cancer patients – A case control study

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2021
Background: Very few studies have been done to evaluate the level of serum immunoglobulins (IgG, IgM, and IgA) in patients with oral cancer as tumor markers. Aims and Objectives: The aim of this study was to estimate the serum immunoglobulins level (IgG,
Vivek M Tarsariya   +5 more
doaj   +1 more source

IgM nephropathy revisited [PDF]

open access: yesNephro-Urology Monthly, 2012
IgM nephropathy (IgMN) is an idiopathic immune complex-mediated glomerulopathy that was first described as a distinct disease in a nephropathology literature in 1978. Here, a historical review and the current status of IgMN in the light of world literature and the current experience will be presented.
Mubarak, Muhammed, Kazi, Javed I
openaire   +2 more sources

Combination Therapy of Curcumin and Disulfiram Synergistically Inhibits the Growth of B16-F10 Melanoma Cells by Inducing Oxidative Stress

open access: yesBiomolecules, 2022
Oxidative stress plays a central role in the pathophysiology of melanoma. Curcumin (CUR) is a polyphenolic phytochemical that stimulates reactive oxygen species (ROS) production, while disulfiram (DSS) is a US FDA-approved drug for the treatment of ...
Sheila S. Fontes   +6 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

P- 81 PREVALENCE OF HEV INFECTION IN HIV CARRIERS, PATIENTS WITH INFLAMMATORY BOWEL DISEASE AND CIRRHOTIC PATIENTS

open access: yesAnnals of Hepatology, 2023
Introduction and Objectives: Hepatitis E is a neglected disease in Brazil. Hepatitis E virus (HEV) can cause chronic illness in immunocompromised patients.
Luan Henrique Paim Santos   +16 more
doaj   +1 more source

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