Results 11 to 20 of about 285,914 (256)

IgM-producing tumors in the BALB/c mouse: a model for B-cell maturation [PDF]

open access: yes, 1974
Five adjuvant induced BALB/c tumors producing IgM—McPc 1748, W 3469, TEPC 183, McPc 774, and Y 5781—were characterized morphologically by electron microscopy, analysis of the distribution of surface-bound and intracytoplasmic IgM using immunofluorescence,
Citronbaum, R.   +7 more
core   +8 more sources

Supplementary Material for: Waldenström macroglobulinemia and non-IgM-type lymphoplasmacytic lymphoma are genetically similar

open access: yes, 2023
Introduction Waldenström macroglobulinemia (WM) represents a subset of lymphoplasmacytic lymphoma (LPL) with the immunoglobulin (Ig)M paraprotein. MYD88 L265P and CXCR4 mutations are common mutations in WM patients, and mutations in ARID1A and KMT2D ...
Kasamatsu T. (14788534)   +10 more
core   +2 more sources

Serological survey of anti-group A rotavirus IgM in UK adults [PDF]

open access: yes, 2003
Rotaviral associated disease of infants in the UK is seasonal and infection in adults not uncommon but the relationship between these has been little explored.
Cox, M. J., Medley, Graham
core   +1 more source

Non-functional immunoglobulin G transcripts in a case of hyper-immunoglobulin M syndrome similar to type 4 [PDF]

open access: yes, 2004
86% of immunoglobulin G (IgG) heavy-chain gene transcripts were found to be non-functional in the peripheral blood B cells of a patient initially diagnosed with common variable immunodeficiency, who later developed raised IgM, whereas no non-functionally
Darlow, J.M.   +5 more
core   +1 more source

Diagnostic evaluation of IgM ELISA and IgM Immunofluorescence assay for the diagnosis of Acute Scrub Typhus in central Nepal

open access: yes, 2020
BACKGROUND: Scrub typhus is an acute febrile illness caused by the obligate intracellular bacterium, Orientia tsutsugamushi. Immunochromatography (ICT) and IgM ELISA are two of the routinely employed antibody based assays for diagnosis of Scrub typhus ...
Parajuli, Keshab   +4 more
core   +1 more source

Effect of LUX and IB on anti-IgM-induced phosphorylation of LYN in SU-DHL-6 cells.

open access: yes, 2023
Cells were pre-treated with vehicle or 1 μM LUX or IB after which they were stimulated with anti-human IgM. LYN immunoprecipitates from these cells were analyzed using antibodies for phospho-Src (Y416) and LYN at the indicated time points in SU-DHL-6 ...
Stephen B. Howell (424989)   +2 more
core   +1 more source

Specific IgM and Regulation of Antibody Responses

open access: yes, 2017
Specific IgM, administered together with the antigen it recognizes, enhances primary antibody responses, formation of germinal centers, and priming for secondary antibody responses.
Heyman, Birgitta,   +3 more
core   +1 more source

Emerging drugs targeting cellular redox homeostasis to eliminate acute myeloid leukemia stem cells

open access: yesRedox Biology, 2023
Acute myeloid leukemia (AML) is a very heterogeneous group of disorders with large differences in the percentage of immature blasts that presently are classified according to the specific mutations that trigger malignant proliferation among thousands of ...
Rafaela G.A. Costa   +6 more
doaj   +1 more source

Lateral-Flow Assay for Rapid Serodiagnosis of Human Leptospirosis [PDF]

open access: yes, 2001
An assay device for the rapid detection of Leptospira-specific immunoglobulin M (IgM) antibodies in human sera is presented. The sensitivity (85.8%) and specificity (93.6%) of the assay compared well (91.9% agreement) with those of an IgM enzyme-linked ...
Smits, H. L.   +20 more
core   +2 more sources

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

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