A novel method to standardise serum IgA measurements shows an increased prevalence of IgA deficiency in young children with recurrent respiratory tract infections [PDF]
Clinical & Translational Immunology, 2021 Objectives While physicians are often confronted with immunoglobulin A (IgA) deficiency in children with recurrent infections, the clinical relevance of this finding is unclear. Large‐scale studies examining the significance of IgA deficiency in children
Mischa H Koenen +13 more
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IgA Antibodies and IgA Deficiency in SARS-CoV-2 Infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 A large repertoire of IgA is produced by B lymphocytes with T-independent and T-dependent mechanisms useful in defense against pathogenic microorganisms and to reduce immune activation.
Isabella Quinti +4 more
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Minimal-moderate variation of human oral virome and microbiome in IgA deficiency [PDF]
Scientific Reports, 2021 Immunoglobulin A (IgA) is the dominant antibody found in our mucosal secretions and has long been recognized to play an important role in protecting our epithelium from pathogens.
Maria José de la Cruz Peña +4 more
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Selective IgA Deficiency a Probable Risk of Recurrent Chest Infections in Asthmatics [PDF]
Journal of Asthma and Allergy, 2021 Fawzia Hassan Abo Ali,1 Nehal Elfawy Mahmoud,1 Amr Yakout Mohamed El-Sayed,1 Mariam Fathy Abdelmaksoud,2 Alaa K Shata,3 Shaimaa Hani Fouad1 1Department of Internal Medicine/Allergy and Clinical Immunology, Ain-Shams University, Cairo, Egypt; 2Department ...
Abo Ali FH +5 more
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The clinical implications of selective IgA deficiency [PDF]
Journal of Translational Autoimmunity, 2019 Selective IgA deficiency (SIgAD) is the most common primary immunodeficiency but does not always result in clinical disease. This may in part be due to the definition based on serum IgA, while most IgA is secreted at mucosal surfaces, not amenable to ...
Samantha Swain +3 more
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Duodenal nodular lymphoid hyperplasia in a patient with IgA deficiency [PDF]
Clinical Case Reports, 2020 Most patients with IgA deficiency are asymptomatic, but duodenal nodular lymphoid hyperplasia is one symptom known to be associated with common variable immunodeficiency (CVID), including selective IgA deficiency and agammaglobulinemia.
Hanae Ida +5 more
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Selective IgA Deficiency and Allergy: A Fresh Look to an Old Story [PDF]
Medicina, 2022 Selective IgA deficiency (SIgAD) is the most common human primary immune deficiency (PID). It is classified as a humoral PID characterized by isolated deficiency of IgA (less than 7 mg/dL but normal serum IgG and IgM) in subjects greater than 4 years of ...
Bianca Laura Cinicola +9 more
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Prevalence of tissue transglutaminase antibodies and IgA deficiency are not increased in juvenile idiopathic arthritis: a case-control study [PDF]
Pediatric Rheumatology Online Journal, 2023 Background The prevalence of Celiac Disease (CD) in Juvenile Idiopathic Arthritis (JIA) has been reported to be 0.1–7% in various small studies.
Angela Taneja Kohli +9 more
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Mixed Pulmonary Infection, Asthma, and Nephrotic Syndrome in a Patient Diagnosed with Selective IgA Deficiency: A Case Report [PDF]
Journal of Inflammation ResearchChenxi Yan, Junke Qiu, Xiaohong Pan, Xiaoqin Huang, Lei Pan, Caihong Wang, Minjie Mao Zhejiang Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Zhejiang, 310003, People’s Republic of ChinaCorrespondence: Minjie Mao, Zhejiang ...
Yan C +6 more
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Prophylaxis of Upper Airway Infections in a Patient with Partial IgA Deficiency: Concurrent Use of Sublingual Immunotherapy with Inactivated Whole-Cell Bacterial Extract and Der p1 [PDF]
Case Reports in Otolaryngology, 2020 Selective IgA deficiency is the most common type of primary immunodeficiency, but there is not yet a specific effective treatment. The most prevalent clinical manifestations are infectious diseases of the respiratory system.
Paula F. Aarestrup +3 more
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