Results 101 to 110 of about 44,820 (149)
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APMIS, 1995
IgA deficiency is the most common humoral defect in man and results in an increased susceptibility to respiratory tract and gastrointestinal infections. Both clinical and genetic data support a close relationship with common variable immunodeficiency, a disease which involves not only IgA and IgG production, but also, in half of the patients, IgM.
L, Truedsson +6 more
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IgA deficiency is the most common humoral defect in man and results in an increased susceptibility to respiratory tract and gastrointestinal infections. Both clinical and genetic data support a close relationship with common variable immunodeficiency, a disease which involves not only IgA and IgG production, but also, in half of the patients, IgM.
L, Truedsson +6 more
openaire +2 more sources
The Indian Journal of Pediatrics, 1982
Of 140 patients referred to the Pediatric Immunology Clinic during of 12-month period with the symptoms of recurrent infections or allergic respiratory illness, 21 (75%) were found to have selective IgA deficiency defined as serum concentration ≤ 5 mg. with normal levels of IgG and IgM.
S, Sahni, G, Woodford, R K, Chandra
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Of 140 patients referred to the Pediatric Immunology Clinic during of 12-month period with the symptoms of recurrent infections or allergic respiratory illness, 21 (75%) were found to have selective IgA deficiency defined as serum concentration ≤ 5 mg. with normal levels of IgG and IgM.
S, Sahni, G, Woodford, R K, Chandra
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IgA Deficiency and Risk of Cancer: A Population-Based Matched Cohort Study [PDF]
To investigate the risk of cancer in individuals with IgA deficiency compared with the general population.Prospective nationwide population-based cohort study.
Weimin Ye +2 more
exaly +2 more sources
Association between selective IgA deficiency and COVID-19 [PDF]
Yuji Naito, Tomohisa Takagi
exaly +2 more sources
Physiology of IgA and IgA Deficiency
Journal of Clinical Immunology, 2001Although secretory immunoglobulin A (IgA) is important in mucosal immunity. selective IgA deficiency is the most common primary immunodeficiency of humans. In most cases this defect is not associated with any illness. The reasons for this are unknown, but other immunological compensations might provide sufficient or complete restitution. Alternatively,
openaire +2 more sources
Current Opinion in Allergy & Clinical Immunology, 2012
To summarize recent publications on clinical and genetic aspects of IgA deficiency (IgAD).Both major histocompatibility complex (MHC) and non-MHC genes contribute to susceptibility to the disease. The former genes appear to be located in different parts of the MHC region depending on the HLA haplotype.
Ning, Wang, Lennart, Hammarström
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To summarize recent publications on clinical and genetic aspects of IgA deficiency (IgAD).Both major histocompatibility complex (MHC) and non-MHC genes contribute to susceptibility to the disease. The former genes appear to be located in different parts of the MHC region depending on the HLA haplotype.
Ning, Wang, Lennart, Hammarström
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JAMA: The Journal of the American Medical Association, 1985
To the Editor.— We have documented 25 cases of acquired immunodeficiency syndrome (AIDS) at our institution since 1982, and two of these patients have had absent serum IgA. Both patients were adult male homosexuals with lymphadenopathy and had reversal of their T-helper/suppressor ratios (0.1 and 0.2, respectively, with a norm for this institution of ...
M, Hepner +3 more
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To the Editor.— We have documented 25 cases of acquired immunodeficiency syndrome (AIDS) at our institution since 1982, and two of these patients have had absent serum IgA. Both patients were adult male homosexuals with lymphadenopathy and had reversal of their T-helper/suppressor ratios (0.1 and 0.2, respectively, with a norm for this institution of ...
M, Hepner +3 more
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IgG4 deficiency in IgA-deficient patients
The Pediatric Infectious Disease Journal, 1989IgG subclass deficiency may be an important factor in the infection proneness of some IgA-deficient subjects. Although several studies on IgG subclass deficiency in IgA-deficient subjects have been reported, most have been unable to assess the incidence of IgG4 deficiency because the limitations of the assay methods used have often made a distinction ...
L J, Beard, A, Ferrante
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IgA Deficiency & Mortality: A Population-Based Cohort Study [PDF]
IgA deficiency has been linked to increased morbidity but data on mortality is lacking. In this population-based prospective cohort study we examined mortality in patients with IgA deficiency compared with the general population.
Lennart Hammarström +2 more
exaly +2 more sources
Anti-IgA antibodies in IgA-deficient children
Journal of Clinical Immunology, 1988IgG and IgM isotype antibodies to polyclonal human IgA, myeloma IgA1, and myeloma IgA2 were estimated in 38 IgA-deficient children aged between 0.9 and 15 years. All children had IgM anti-IgA antibodies. IgG antibodies against either polyclonal IgA, IgA1, or IgA2 were present in 63% of the IgA-deficient children.
F H, Sennhauser +5 more
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