Results 111 to 120 of about 44,820 (149)
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Suppressor cells and IgA deficiency
Clinical Immunology and Immunopathology, 1978Abstract Regulator cell function and terminal differentiation of B lymphocytes in six patients with selective IgA deficiency were evaluated. Suppression of IgA synthesis was determined by in vitro pokeweed mitogen-stimulated cell cultures in which IgA-deficient and control lymphocytes were cocultured for 7 days. IgA synthesis was measured by double
J S, Atwater, T B, Tomasi
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Annals of allergy, 1991
IgA deficiency, the most common primary immunodeficiency, is a very heterogeneous clinical disorder which may be associated with a variety of infections, allergies, autoimmune disorders, gastrointestinal diseases, and genetic disorders. The central phenotypic feature of this immunodeficiency is a B cell differentiation arrest, the extent of which may ...
W, Strober, M C, Sneller
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IgA deficiency, the most common primary immunodeficiency, is a very heterogeneous clinical disorder which may be associated with a variety of infections, allergies, autoimmune disorders, gastrointestinal diseases, and genetic disorders. The central phenotypic feature of this immunodeficiency is a B cell differentiation arrest, the extent of which may ...
W, Strober, M C, Sneller
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Selective IgA Deficiency and Neoplasia
Vox Sanguinis, 1980From the Immunodeficiency Cancer Registry, it has appeared that there is an increasing frequency of neoplasia in individuals who have a selective absence of serum IgA. Approaching this question from another point of view, we have found that of 4,120 sera drawn in this cancer-oriented hospital, 12 sera had a total absence of IgA and 3 additional sera ...
C, Cunningham-Rundles +3 more
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Gm ALLOTYPES IN IgA DEFICIENCY
International Journal of Immunogenetics, 1985SUMMARYGm phenotypes were examined in 90 Swedish IgA‐deficient (<0.05 g/litre of serum IgA) donors and 40 normal first and second degree relatives of six of these donors. The Glm1,2, G3m5 and Km1 frequency in the group of IgA‐deficient donors did not differ from that found in the normal population. Among the relatives, HLA and/or Gm identical normal
L, Hammarström, R, Grubb, C I, Smith
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IgA Deficiency and Influenza Infection
Scandinavian Journal of Immunology, 1976A prospective study of influenza infection was carried out on 90 blood donors deficient for serum IgA as tested with double immunodiffusion. Half of them lacked IgA even by radioimmunoassay (RIA). A correlation existed between serum haemagglutination‐inhibiting (HI) antibody and resistance to infection, suggesting that the serum HI antibody was an ...
K, Aho, R, Pyhälä, J, Koistinen
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Oral Manifestations of IgA Deficiency
1974The IgA system is viewed as a major local defense mechanism of mucous membranes, and IgA deficiency seems to be a significant predisposing factor to a variety of sino-pulmonary infections and intestinal disorders (1–6). Since IgA is the predominant immunoglobulin in secretions (7–10), including saliva, a protective role for this class of ...
P B, Robertson, M D, Cooper
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Selective IgA deficiency in the dog
Clinical Immunology and Immunopathology, 1985This study documents the occurrence of selective IgA deficiency in the dog. This is a unique spontaneous animal model with clinical and immunologic findings similar to that of selective IgA deficiency in humans, the most common human primary immunodeficiency.
P J, Felsburg, L T, Glickman, P F, Jezyk
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Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001
Selective IgA deficiency is the most common primary immunodeficiency, with a prevalence of approximately 1/600 in whites. Most subjects are asymptomatic but some may suffer from frequent respiratory and gastrointestinal infections. Patients who suffer from frequent infections usually have a defect in antibody responses toward polysaccharides, which is ...
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Selective IgA deficiency is the most common primary immunodeficiency, with a prevalence of approximately 1/600 in whites. Most subjects are asymptomatic but some may suffer from frequent respiratory and gastrointestinal infections. Patients who suffer from frequent infections usually have a defect in antibody responses toward polysaccharides, which is ...
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The heterogeneity of IgA deficiency
Journal of Clinical Immunology, 1988L A, Hanson +4 more
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