Results 201 to 210 of about 41,598 (251)
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IgA deficiency and autoimmunity
Autoimmunity Reviews, 2014IgA is the most abundant immunoglobulin in the human body, and performs a very specialized role which involves mucosal immunity, development of tolerance and protection against infection. IgA is the key immunoglobulin in the respiratory and gastrointestinal tracts, which provide the most intimate interface between the environment and self.
Karmtej, Singh +2 more
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Annals of allergy, 1991
IgA deficiency, the most common primary immunodeficiency, is a very heterogeneous clinical disorder which may be associated with a variety of infections, allergies, autoimmune disorders, gastrointestinal diseases, and genetic disorders. The central phenotypic feature of this immunodeficiency is a B cell differentiation arrest, the extent of which may ...
W, Strober, M C, Sneller
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IgA deficiency, the most common primary immunodeficiency, is a very heterogeneous clinical disorder which may be associated with a variety of infections, allergies, autoimmune disorders, gastrointestinal diseases, and genetic disorders. The central phenotypic feature of this immunodeficiency is a B cell differentiation arrest, the extent of which may ...
W, Strober, M C, Sneller
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JAMA: The Journal of the American Medical Association, 1985
To the Editor.— We have documented 25 cases of acquired immunodeficiency syndrome (AIDS) at our institution since 1982, and two of these patients have had absent serum IgA. Both patients were adult male homosexuals with lymphadenopathy and had reversal of their T-helper/suppressor ratios (0.1 and 0.2, respectively, with a norm for this institution of ...
M, Hepner +3 more
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To the Editor.— We have documented 25 cases of acquired immunodeficiency syndrome (AIDS) at our institution since 1982, and two of these patients have had absent serum IgA. Both patients were adult male homosexuals with lymphadenopathy and had reversal of their T-helper/suppressor ratios (0.1 and 0.2, respectively, with a norm for this institution of ...
M, Hepner +3 more
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APMIS, 1995
IgA deficiency is the most common humoral defect in man and results in an increased susceptibility to respiratory tract and gastrointestinal infections. Both clinical and genetic data support a close relationship with common variable immunodeficiency, a disease which involves not only IgA and IgG production, but also, in half of the patients, IgM.
L, Truedsson +6 more
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IgA deficiency is the most common humoral defect in man and results in an increased susceptibility to respiratory tract and gastrointestinal infections. Both clinical and genetic data support a close relationship with common variable immunodeficiency, a disease which involves not only IgA and IgG production, but also, in half of the patients, IgM.
L, Truedsson +6 more
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IgG4 deficiency in IgA-deficient patients
The Pediatric Infectious Disease Journal, 1989IgG subclass deficiency may be an important factor in the infection proneness of some IgA-deficient subjects. Although several studies on IgG subclass deficiency in IgA-deficient subjects have been reported, most have been unable to assess the incidence of IgG4 deficiency because the limitations of the assay methods used have often made a distinction ...
L J, Beard, A, Ferrante
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Anti-IgA antibodies in IgA-deficient children
Journal of Clinical Immunology, 1988IgG and IgM isotype antibodies to polyclonal human IgA, myeloma IgA1, and myeloma IgA2 were estimated in 38 IgA-deficient children aged between 0.9 and 15 years. All children had IgM anti-IgA antibodies. IgG antibodies against either polyclonal IgA, IgA1, or IgA2 were present in 63% of the IgA-deficient children.
F H, Sennhauser +5 more
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2020
IgA deficiency (D-IgA) in the paediatric population is often an occasional finding during tests performed for other reasons in children in whom an immunodeficiency disorder is not suspected. D-IgA is the most common primary immunodeficiency with a variable prevalence according to ethnicity, estimated on 1 case/600 in the Caucasian population.
Guiducci C., Marchetti F.
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IgA deficiency (D-IgA) in the paediatric population is often an occasional finding during tests performed for other reasons in children in whom an immunodeficiency disorder is not suspected. D-IgA is the most common primary immunodeficiency with a variable prevalence according to ethnicity, estimated on 1 case/600 in the Caucasian population.
Guiducci C., Marchetti F.
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Gm ALLOTYPES IN IgA DEFICIENCY
International Journal of Immunogenetics, 1985SUMMARYGm phenotypes were examined in 90 Swedish IgA‐deficient (<0.05 g/litre of serum IgA) donors and 40 normal first and second degree relatives of six of these donors. The Glm1,2, G3m5 and Km1 frequency in the group of IgA‐deficient donors did not differ from that found in the normal population. Among the relatives, HLA and/or Gm identical normal
L, Hammarström, R, Grubb, C I, Smith
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La Revue de medecine interne, 2021
Selective IgA deficiency (SIgAD) is defined by the European Society for Immunodeficiencies (ESID) as a serum IgA of less than 0.07g/L in patients greater than 4 years old with normal levels of IgG and IgM, normal vaccine responses, and with the exclusion of secondary causes of hypogammaglobulinemia.
L, Luca +4 more
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Selective IgA deficiency (SIgAD) is defined by the European Society for Immunodeficiencies (ESID) as a serum IgA of less than 0.07g/L in patients greater than 4 years old with normal levels of IgG and IgM, normal vaccine responses, and with the exclusion of secondary causes of hypogammaglobulinemia.
L, Luca +4 more
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Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001
Selective IgA deficiency is the most common primary immunodeficiency, with a prevalence of approximately 1/600 in whites. Most subjects are asymptomatic but some may suffer from frequent respiratory and gastrointestinal infections. Patients who suffer from frequent infections usually have a defect in antibody responses toward polysaccharides, which is ...
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Selective IgA deficiency is the most common primary immunodeficiency, with a prevalence of approximately 1/600 in whites. Most subjects are asymptomatic but some may suffer from frequent respiratory and gastrointestinal infections. Patients who suffer from frequent infections usually have a defect in antibody responses toward polysaccharides, which is ...
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