Results 231 to 240 of about 542,367 (279)

Selective IgA deficiency

The Indian Journal of Pediatrics, 1982
Of 140 patients referred to the Pediatric Immunology Clinic during of 12-month period with the symptoms of recurrent infections or allergic respiratory illness, 21 (75%) were found to have selective IgA deficiency defined as serum concentration ≤ 5 mg. with normal levels of IgG and IgM.
S, Sahni, G, Woodford, R K, Chandra
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Genetics of IgA deficiency

APMIS, 1995
IgA deficiency is the most common humoral defect in man and results in an increased susceptibility to respiratory tract and gastrointestinal infections. Both clinical and genetic data support a close relationship with common variable immunodeficiency, a disease which involves not only IgA and IgG production, but also, in half of the patients, IgM.
L, Truedsson, B, Baskin, Q, Pan, H, Rabbani, I, Vorĕchovský, C I, Smith, L, Hammarström   +6 more
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Endocrinopathy and IgA deficiency

Clinical Immunology and Immunopathology, 1973
Abstract Three cases of IgA deficiency occurring in association with endocrine hypofunction—Turner's syndrome, hypothyroidism, and diabetes—are described. The significance of IgA deficiency associated with chromosome abnormalities are discussed in view of the present finding of IgA deficiency in a patient with Turner's syndrome displaying a karyotype
H K, Silver, J, Shuster, P, Gold, D, Hawkins, S O, Freedman   +4 more
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Physiology of IgA and IgA Deficiency

Journal of Clinical Immunology, 2001
Although secretory immunoglobulin A (IgA) is important in mucosal immunity. selective IgA deficiency is the most common primary immunodeficiency of humans. In most cases this defect is not associated with any illness. The reasons for this are unknown, but other immunological compensations might provide sufficient or complete restitution. Alternatively,
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IgA deficiency

Current Opinion in Allergy & Clinical Immunology, 2012
To summarize recent publications on clinical and genetic aspects of IgA deficiency (IgAD).Both major histocompatibility complex (MHC) and non-MHC genes contribute to susceptibility to the disease. The former genes appear to be located in different parts of the MHC region depending on the HLA haplotype.
Ning, Wang, Lennart, Hammarström
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IgA Deficiency and AIDS

JAMA: The Journal of the American Medical Association, 1985
To the Editor.— We have documented 25 cases of acquired immunodeficiency syndrome (AIDS) at our institution since 1982, and two of these patients have had absent serum IgA. Both patients were adult male homosexuals with lymphadenopathy and had reversal of their T-helper/suppressor ratios (0.1 and 0.2, respectively, with a norm for this institution of ...
M, Hepner, J, Jundt, E, Fisher, D R, Ownby   +3 more
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IgG4 deficiency in IgA-deficient patients

The Pediatric Infectious Disease Journal, 1989
IgG subclass deficiency may be an important factor in the infection proneness of some IgA-deficient subjects. Although several studies on IgG subclass deficiency in IgA-deficient subjects have been reported, most have been unable to assess the incidence of IgG4 deficiency because the limitations of the assay methods used have often made a distinction ...
L J, Beard, A, Ferrante
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Anti-IgA antibodies in IgA-deficient children

Journal of Clinical Immunology, 1988
IgG and IgM isotype antibodies to polyclonal human IgA, myeloma IgA1, and myeloma IgA2 were estimated in 38 IgA-deficient children aged between 0.9 and 15 years. All children had IgM anti-IgA antibodies. IgG antibodies against either polyclonal IgA, IgA1, or IgA2 were present in 63% of the IgA-deficient children.
F H, Sennhauser, C S, Hosking, C L, Jones, R A, MacDonald, N, Mermelstein, D M, Roberton   +5 more
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Suppressor cells and IgA deficiency

Clinical Immunology and Immunopathology, 1978
Abstract Regulator cell function and terminal differentiation of B lymphocytes in six patients with selective IgA deficiency were evaluated. Suppression of IgA synthesis was determined by in vitro pokeweed mitogen-stimulated cell cultures in which IgA-deficient and control lymphocytes were cocultured for 7 days. IgA synthesis was measured by double
J S, Atwater, T B, Tomasi
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FAMILIAL SELECTIVE IgA DEFICIENCY

Pediatrics, 1972
Thirteen subjects with selective IgA deficiency were obtained from five separate families. In three families an autosomal recessive inheritance was apparent while an autosomal dominant inheritance appeared very likely in the two remaining families. An increased incidence of quantitative defects in immunoglobulin synthesis was seen in ...
P A, Nell, A J, Ammann, R, Hong, E R, Stiehm   +3 more
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