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Annals of allergy, 1991
IgA deficiency, the most common primary immunodeficiency, is a very heterogeneous clinical disorder which may be associated with a variety of infections, allergies, autoimmune disorders, gastrointestinal diseases, and genetic disorders. The central phenotypic feature of this immunodeficiency is a B cell differentiation arrest, the extent of which may ...
W, Strober, M C, Sneller
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IgA deficiency, the most common primary immunodeficiency, is a very heterogeneous clinical disorder which may be associated with a variety of infections, allergies, autoimmune disorders, gastrointestinal diseases, and genetic disorders. The central phenotypic feature of this immunodeficiency is a B cell differentiation arrest, the extent of which may ...
W, Strober, M C, Sneller
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Selective IgA deficiency in the dog
Clinical Immunology and Immunopathology, 1985This study documents the occurrence of selective IgA deficiency in the dog. This is a unique spontaneous animal model with clinical and immunologic findings similar to that of selective IgA deficiency in humans, the most common human primary immunodeficiency.
P J, Felsburg, L T, Glickman, P F, Jezyk
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Selective IgA Deficiency and Neoplasia
Vox Sanguinis, 1980From the Immunodeficiency Cancer Registry, it has appeared that there is an increasing frequency of neoplasia in individuals who have a selective absence of serum IgA. Approaching this question from another point of view, we have found that of 4,120 sera drawn in this cancer-oriented hospital, 12 sera had a total absence of IgA and 3 additional sera ...
C, Cunningham-Rundles +3 more
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Oral Manifestations of IgA Deficiency
1974The IgA system is viewed as a major local defense mechanism of mucous membranes, and IgA deficiency seems to be a significant predisposing factor to a variety of sino-pulmonary infections and intestinal disorders (1–6). Since IgA is the predominant immunoglobulin in secretions (7–10), including saliva, a protective role for this class of ...
P B, Robertson, M D, Cooper
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IgA Deficiency and Influenza Infection
Scandinavian Journal of Immunology, 1976A prospective study of influenza infection was carried out on 90 blood donors deficient for serum IgA as tested with double immunodiffusion. Half of them lacked IgA even by radioimmunoassay (RIA). A correlation existed between serum haemagglutination‐inhibiting (HI) antibody and resistance to infection, suggesting that the serum HI antibody was an ...
K, Aho, R, Pyhälä, J, Koistinen
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Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001
Selective IgA deficiency is the most common primary immunodeficiency, with a prevalence of approximately 1/600 in whites. Most subjects are asymptomatic but some may suffer from frequent respiratory and gastrointestinal infections. Patients who suffer from frequent infections usually have a defect in antibody responses toward polysaccharides, which is ...
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Selective IgA deficiency is the most common primary immunodeficiency, with a prevalence of approximately 1/600 in whites. Most subjects are asymptomatic but some may suffer from frequent respiratory and gastrointestinal infections. Patients who suffer from frequent infections usually have a defect in antibody responses toward polysaccharides, which is ...
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The heterogeneity of IgA deficiency
Journal of Clinical Immunology, 1988L A, Hanson +4 more
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