Results 41 to 50 of about 15,557 (223)

Characterization of scrotal involvement in children and adolescents with IgA vasculitis

Advances in Rheumatology, 2018
Objective To characterize scrotal involvement in children and adolescents with IgA vasculitis. Methods A cross-sectional retrospective study included 296 IgA vasculitis (EULAR/PRINTO/PRES criteria) patients, 150/296 (51%) were males and assessed by ...
Izabel M. Buscatti, Henrique M. Abrão, Katia Kozu, Victor L. S. Marques, Roberta C. Gomes, Adriana M. E. Sallum, Clovis A. Silva   +6 more
doaj   +1 more source

Serological Measurement of Poly-IgA Immune Complex Levels in IgA Nephropathy and IgA Vasculitis

Bio-Protocol, 2022
Both IgA nephropathy and IgA vasculitis, formerly known as Henoch-Schӧnlein purpura, are immune deposition diseases. IgA nephropathy is caused by the deposition of aberrantly formed poly-IgA complexes from blood circulation to the kidney glomerulus; IgA ...
Xue Zhang, Jicheng Lv, Pan Liu, Xinfang Xie, Xinyan Li, Hong Zhang, Jing Jin   +6 more
doaj   +1 more source

Neutrophil Extracellular Traps are Present in Immune-complex-mediated Cutaneous Small Vessel Vasculitis and Correlate with the Production of Reactive Oxygen Species and the Severity of Vessel Damage

Acta Dermato-Venereologica, 2020
Formation of neutrophil extracellular traps has been implicated in autoimmunity. However, the presence and clinical relevance of neutrophil extracellular traps in immune-complex-mediated cutaneous small and medium vessel vasculitides has not been ...
Christina Bergqvist, Rémi Safi, George El Hasbani, Ossama Abbas, Abdulghani Kibbi, Dany Nassar   +5 more
doaj   +1 more source

Taxonomic and functional shifts of gut microbiome in immunoglobulin A vasculitis children and their mothers

Frontiers in Pediatrics
ObjectivesTo examine the gut microbiota characteristics in children with immunoglobulin A vasculitis and their interrelationships with the host, while evaluate the vertical inheritance of microbiota in the development and progression of IgA vasculitis ...
Yijia Liang, Changying Zhao, Lanlan Zhao, Dashuang Sheng, Bin Chen, Guoping Zhao, Guoping Zhao, Guoping Zhao, Qinghua Wang, Lei Zhang, Lei Zhang   +10 more
doaj   +1 more source

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

Advanced Science, EarlyView.
This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi, Zhijiao Li, Xin Ma, Bei Zhang, Xinfeng Wu, Hua Fan, Rongzeng Liu, Hongwei Jiang, Cong‐Qiu Chu   +8 more
wiley   +1 more source

Kidney injury and colocalization of complement C3, IgA, and IgG in glomerular immune-complex deposits of patients with IgA nephropathy or IgA vasculitis with nephritis. [PDF]

Kidney Int
Novak L, Hall SD, Cutter G, Gurganus GL, Rizk DV, Julian BA, Haas M, Novak J.   +7 more
europepmc   +3 more sources

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Neutrophil-to-lymphocyte ratio: A biomarker for predicting systemic involvement in iga vasculitis

Indian Journal of Rheumatology, 2020
Context:“IgA vasculitis, is an immune complex mediated, self limited cutaneous small vessel vasculitis, characterized by palpable purpurae, arthralgia or arthritis, gastrointestinal and/or renal involvement.” Systemic involvement is considered to be the ...
Rintu Merin George, Arun C Inamadar, Ajit B Janagond   +2 more
doaj   +1 more source

Glucocorticoids in IgA vasculitis

Acta Medica
IgA vasculitis (IgAV) is an immune complex vasculitis affecting small vessels characterized by IgA1 immune deposits. IgA vasculitis typically resolves spontaneously in most cases, especially in pediatric cases but may have more severe outcomes in adults and the optimal treatment for IgAV remains controversial.
Berkan Armağan
openalex   +3 more sources

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source