Results 291 to 300 of about 455,260 (321)
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Current Opinion in Immunology, 2001
IgE receptors are implicated as important components of the immunological pathway in allergic and inflammatory diseases. Recent investigations have begun to unravel the structure, signal transduction and function of IgE receptors from different cell types in rodent and human systems.
N, Novak, S, Kraft, T, Bieber
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IgE receptors are implicated as important components of the immunological pathway in allergic and inflammatory diseases. Recent investigations have begun to unravel the structure, signal transduction and function of IgE receptors from different cell types in rodent and human systems.
N, Novak, S, Kraft, T, Bieber
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Association of asthma with serum IgE levels and skin-test reactivity to allergens.
New England Journal of Medicine, 1989We investigated the association of self-reported asthma or allergic rhinitis with serum IgE levels and skin-test reactivity to allergens in 2657 subjects in a general-population study. Regardless of the subjects' status with respect to atopy or their age
B. Burrows +4 more
semanticscholar +1 more source
IG‐G, IG‐A AND IG‐M GRANULOCYTE‐REACTIVE ANTINUCLEAR FACTORS IN RHEUMATOID ARTHRITIS
Acta Medica Scandinavica, 1968Abstract Sera from 84 patients with rheumatoid arthritis were investigated for Ig, Ig‐G, Ig‐A, Ig‐M ANF reactive with nuclei of polymorphonuclear granulocytes, using a two‐ and three‐layer immunofluorescent antibody technique.Granulocyte‐reactive ANF were found in 2/3 of the sera.
H. Graudal, P. Elling
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Preparation of rabbit anti-IgE for use in radioimmunoassays of total IgE and specific IgE antibodies
Journal of Immunological Methods, 1978Abstract Detailed methodology for preparing and testing isolated rabbit anti-human IgE suitable for radioimmunoassays of total IgE and specific IgE antibodies is presented in a single article for the first time. A method for obtaining a product free of anti-idiotype antibodies is also described.
Wai Ying Lee, Douglas C. Heiner
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IgE and IgE Antibody to Mite in Nasal Fluid
ORL, 1975The levels of total IgE and IgE antibodies to mite per unit quantity of nasal fluid were successfully determined by our special method of collecting nasal fluid. The mean value of IgE was 80 +/- 101 U/ml, and that of IgE Ab 1.45 +/- 1.29/ml (RAST score) in NF.
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A high‐affinity monoclonal anti‐IgE antibody for depletion of IgE and IgE‐bearing cells
Allergy, 2008Background: We have identified a monoclonal anti‐human immunoglobulin E (IgE) antibody, which recognizes FcepsilonRI‐bound IgE and prevents binding of IgE to FcepsilonRI. In this study, we assessed the binding kinetics and affinity of monoclonal antibody 12 (mAb12) for IgE and investigated whether mAb12 can be used for depletion of IgE and isolation ...
Christian Lupinek +11 more
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IgE and non-IgE mechanisms in ocular allergy.
Annals of allergy, 1993Various forms of conjunctival disease have traditionally been referred to by the umbrella term "allergic conjunctivitis," on the assumption that they are all caused by a Gell and Coombs type I hypersensitivity reaction. Recent evidence disputes this classification, however, and suggests that other mechanisms may also be responsible for the complex ...
BONINI, Sergio, BONINI S.
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Eosinophilic esophagitis in adults is associated with IgG4 and not mediated by IgE.
Gastroenterology, 2014BACKGROUND & AIMS Eosinophilic esophagitis is usually triggered by foods, by unclear mechanisms. We evaluated the roles of IgE and IgG4 in the development of eosinophilic esophagitis.
F. Clayton +11 more
semanticscholar +1 more source
Human Antibodies, 1996
Immunoglobulin E plays a central role in mediating the pathology of allergic disease. Conversely, it is involved in the normal protective immune responses against parasite infection. Both these biological processes depend on interaction between the variable regions (VH and VL) of IgE antibodies and target antigen.
Rachel E. Snow +3 more
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Immunoglobulin E plays a central role in mediating the pathology of allergic disease. Conversely, it is involved in the normal protective immune responses against parasite infection. Both these biological processes depend on interaction between the variable regions (VH and VL) of IgE antibodies and target antigen.
Rachel E. Snow +3 more
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IgE-Binding Factors And Regulation Of The IgE Antibody Response
Annual Review of Immunology, 1988In rodents, IgE-bF are derived from a subset of T cells that bear Fc epsilon R or Fc gamma R, or both, and selectively enhance or suppress the IgE response. IgE-PF and IgE-SF may share a common structural gene, therefore a common polypeptide chain, and their biologic activities are decided by post-translational glycosylation process.
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