Results 171 to 180 of about 19,264 (196)

IGF-1-mediated FOXC1 overexpression induces stem-like properties through upregulating CBX7 and IGF-1R in esophageal squamous cell carcinoma. [PDF]

Cell Death Discov
Wu H, Li ZX, Fang K, Zhao ZY, Sun MC, Feng AQ, Leng ZY, Zhang ZH, Chu Y, Zhang L, Chen T, Xu MD.   +11 more
europepmc   +1 more source

Expression of IGF-1R in Skin Wound Healing Treated by Topical Application of Cinnamomum Zeylanicum

Noor Natik Raheem, Lobna K. Al Khafaji, Lehadh M. Al-Azzawi, Dhifaf Kamil Kadhim Al-Thahab   +3 more
openalex   +2 more sources

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IGF-1R tyrosine kinase expression and dependency in clones of IGF-1R knockout cells (R−)

Biochemical and Biophysical Research Communications, 2006
Insulin-like growth factor 1 receptor (IGF-1R) plays many crucial roles in cancer, like anti-apoptotic activity and necessity for transformation. IGF-1R knockout cells (R-) represent a useful tool for molecular mapping of biological properties of the receptor.
Linda, Rosengren, Daiana, Vasilcanu, Radu, Vasilcanu, Sandra, Fickenscher, Bita, Sehat, Nathalia, Natalishvili, Sean, Naughton, Shucheng, Yin, Ada, Girnita, Leonard, Girnita, Magnus, Axelson, Olle, Larsson   +11 more
openaire   +2 more sources

Transactivation of the IGF-1R by aldosterone

American Journal of Physiology-Renal Physiology, 2007
Activation of epithelial sodium channels (ENaC) by aldosterone, insulin, or insulin-like growth factor-1 (IGF-1) in renal epithelial cells (including the Xenopus laevis renal cell line A6) appears to share some common signaling elements subsequent to the initial insulin or IGF-1 receptor activation.
Jennifer L, Holzman, Lian, Liu, Billie Jeanne, Duke, Alexandra E, Kemendy, Douglas C, Eaton   +4 more
openaire   +2 more sources

IGF-1R mRNA expression is increased in obese children

Growth Hormone & IGF Research, 2018
Obese children are often taller than age-matched subjects. Reports on GH and IGF-I levels in obese individuals are controversial, with normal and reduced GH-IGF-I levels having been reported in this group of patients. Thus, the aim of this study was to analyse insulin-like growth factor type 1 receptor (IGF-IR) mRNA expression in obese children.Forty ...
Rafaela Cristina, Ricco, Rubens Garcia, Ricco, Mariangela Carletti, Queluz, Mariana Teresa Sarti, de Paula, Patricia Volpon, Atique, Rodrigo José, Custódio, Hugo, Tourinho Filho, Raphael, Del Roio Liberatori, Carlos Eduardo, Martinelli   +8 more
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Abstract 1631: Tumorigenicity of IGF-1R and IR: Rationale for co-targeting IGF-1R and IR in cancer

Cancer Research, 2011
Abstract The Type 1 insulin-like growth factor receptor (IGF-1R) is a well established mediator of tumor cell proliferation and survival. IGF-1R is required for cellular transformation by a number of oncogenes including Ras, and expression of IGF-1R can promote tumor formation in vivo.
Lorena Lerner, Qing Liu, Nianjun Tao, John Yang, Eric Brown, Susan Koujak, Brian Krieger, Lu Huang, Maryland Rosenfeld-Franklin, Mark Miglarese, Jonathan Pachter, Murray O. Robinson, M. Isabel Chiu, David Epstein, Elizabeth Buck   +14 more
openaire   +1 more source