Results 1 to 10 of about 231,978 (311)

Neuroprotection of IGF-1 in neonatal hypoxic-ischemic brain injury through downregulation of FoXO3a-PUMA pathway [PDF]

open access: yesFrontiers in Cellular Neuroscience
Insulin-like growth factor-1 (IGF-1) is a single chain polypeptide hormone that plays an essential role in intrauterine and postnatal growth. Recent studies suggest that IGF-1 and its receptor IGF-1R are involved in the pathogenesis of neurological ...
Yanli Tang   +12 more
doaj   +2 more sources

Un viaggio nella Gestalt: come cambia il benessere durante il percorso gestaltico

open access: yesPhenomena Journal, 2023
Questo lavoro riporta alcuni risultati preliminari di un progetto di ricerca volto a indagare il rapporto tra il benessere percepito e il lavoro personale in psicoterapia della Gestalt.
Stefano Roti 1 , Francesca Berti 1 , Nino Geniola2 , Susanna Zajotti 1 , Giulia Calvaresi 1 , Matteo Defraia1 , Alessandro Cini 1
doaj   +1 more source

Research progress of IGF‐1 and cerebral ischemia

open access: yesIbrain, 2021
Cerebral ischemic disease is a group of diseases that cause insufficient blood supply to the cerebrum, cerebellum or brain stem for different reasons, resulting in corresponding nervous system symptoms.
Shun‐Lian Li   +3 more
doaj   +1 more source

The IGF-1 Signaling Pathway in Viral Infections

open access: yesViruses, 2021
Insulin-like growth factor-1 (IGF-1) and the IGF-1 receptor (IGF-1R) belong to the insulin-like growth factor family, and IGF-1 activates intracellular signaling pathways by binding specifically to IGF-1R.
Agata Józefiak   +3 more
doaj   +1 more source

New insights on the cardiovascular effects of IGF-1

open access: yesFrontiers in Endocrinology, 2023
IntroductionCardiovascular (CV) disorders are steadily increasing, making them the world’s most prevalent health issue. New research highlights the importance of insulin-like growth factor 1 (IGF-1) for maintaining CV healthMethodsWe searched PubMed and ...
Mirjana Macvanin   +7 more
doaj   +1 more source

Pan-Cancer Analysis of IGF-1 and IGF-1R as Potential Prognostic Biomarkers and Immunotherapy Targets

open access: yesFrontiers in Oncology, 2021
AimInsulin-like growth factor-1 receptor (IGF-1R) is one of the main members of the tyrosine protein kinase receptor family. This receptor binds insulin-like growth factor-1 (IGF-1) with a high affinity. IGF-1 is a member of a family of proteins involved
Yinqi Zhang   +17 more
doaj   +1 more source

Elevated serum concentrations of IGF-1 and IGF-1R in patients with thyroid cancers

open access: yesBiomedical Papers, 2020
Background: The rising incidence of thyroid cancer observed in the last few decades requires an improvement in diagnostic tools and management techniques for patients with thyroid nodules. Aims: The aim of this study was to assess serum concentrations of
Hanna Lawnicka   +7 more
doaj   +1 more source

IGF-1 and cardiovascular disease [PDF]

open access: yesGrowth Hormone & IGF Research, 2019
Atherosclerosis is an inflammatory arterial pathogenic condition, which leads to ischemic cardiovascular diseases, such as coronary artery disease and myocardial infarction, stroke, and peripheral arterial disease. Atherosclerosis is a multifactorial disorder and its pathophysiology is highly complex.
Yusuke, Higashi   +3 more
openaire   +2 more sources

Genetic and dietary determinants of insulin-like growth factor (IGF)-1 and IGF binding protein (BP)-3 levels among Chinese women. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Higher insulin-like growth factor (IGF)-1 and lower IGF binding protein (BP)-3 levels have been associated with higher commoncancer risk, including breast cancer.
Qiong Wang   +9 more
doaj   +1 more source

Gut Microbiota and IGF-1 [PDF]

open access: yesCalcified Tissue International, 2018
Microbiota and their hosts have coevolved for millions of years. Microbiota are not only critical for optimal development of the host under normal physiological growth, but also important to ensure proper host development during nutrient scarcity or disease conditions.
Jing Yan, Julia F. Charles
openaire   +2 more sources

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