Results 121 to 130 of about 115,801 (264)

Circulating levels of insulin-like growth factor I (IGF-I) and risk of multiple myeloma: An observational and Mendelian randomisation study. [PDF]

Br J Haematol
Benavente Y, Hermosa S, Papadimitriou N, Clay-Gilmour A, Brown EE, Hofmann JN, Rothman N, Lan Q, Berndt SI, Albanes D, Purdue M, Machiela MJ, Chanock SJ, Bhatti P, Cozen W, Norman A, Slager SL, Cerhan JR, Rajkumar V, Kumar SK, Vachon CM, Novak AJ, Habermann TM, Link BK, Salles G, Ghesquieres H, Bracci PM, Holly E, Griffin RG, Hildebrandt MAT, Vermeulen RCH, Kolijn PM, Hjalgrim H, Smedby KE, Jayasekara H, Cheah S, Monnereau A, Chen Y, Arslan A, Zhang Y, Camp NJ, Sborov DW, Osman AEG, Ziv E, De Vivo I, Joseph V, Teras LR, Patel AV, Kane E, Vajdic CM, Guilloteau A, Cocco P, Alemany L, Sainz J, McKay J, Birmann BM, Casabonne D.   +56 more
europepmc   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

Hepatic Expression of Growth Hormone Receptor (<i>GHrec</i>) and Insulin-like Growth Factor-I (<i>IGF-I</i>) Genes and Cellular Location of <i>IGF-I</i> mRNA in Diploid and Triploid Atlantic Salmon (<i>Salmo salar</i>) Undergoing Parr-Smolt Transformation. [PDF]

Animals (Basel)
Bortoletti M, Fonsatti E, Maccatrozzo L, Peruzzi S, Jobling M, Vascellari M, Radaelli G, Bertotto D.   +7 more
europepmc   +1 more source

Twenty‐four month clinical outcomes of modified coronally advanced tunnel technique with leukocyte‐ and platelet‐rich fibrin–functionalized porcine dermal matrix for single/multiple gingival recessions

Journal of Periodontology, EarlyView.
Abstract Background To report 24‐month clinical and 3D outcomes of single and multiple RT1 and RT2 gingival recessions treated with the modified coronally advanced tunnel (MCAT) technique and an L‐PRF‐functionalized porcine dermal matrix (PDM), as long‐term data on PDM in root coverage are scarce.
Erik Würflein, Katharina Herrmann, Anton Sculean, Kirstin Vach, Katja Nelson, Tobias Fretwurst, Gerhard Iglhaut, Florian Kernen   +7 more
wiley   +1 more source

Effects of Supplemental Effective Microorganisms in Feed on the Growth, Lipid Deposition and GH-IGF-I Axis of the Blunt Snout Bream <i>Megalobrama amblycephala</i>. [PDF]

Aquac Nutr
Zhu H, Wu F, Che X, Xiao J.
europepmc   +1 more source

ACE‐inhibitory peptide Leu‐Tyr‐Ala in skeletal muscle actin exhibits anti‐aging effects through the inhibition of acn‐1 in Caenorhabditis elegans

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Inhibitors of angiotensin‐converting enzyme (ACE) are used in pharmaceuticals and functional foods. Captopril, a well‐known ACE inhibitor, extends the lifespan of the nematode Caenorhabditis elegans. Bioactive peptides derived from food sources are considered safe ACE inhibitors.
Issei Yokoyama, Minori Yamane, Kanaho Watanabe, Abdul Fatah, Yusuke Komiya, Jun Nagasao, Keizo Arihara   +6 more
wiley   +1 more source

Impact of GH and IGF-I excess on nervous and vascular retinal structure in newly diagnosed acromegaly patients. [PDF]

Pituitary
Pirchio R, Auriemma RS, Cennamo G, Montorio D, Solari D, Cavallo LM, Pivonello R, Colao A.   +7 more
europepmc   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Aging and IGF-I: relationships with vitamin D and body composition. A mediation analysis. [PDF]

Front Nutr
Vicinanza R, Frizza A, Pollard JA, Mazza V, De Martino MU, Imbimbo G, Pignatelli P, Ettorre E, Del Ben M, Molfino A.   +9 more
europepmc   +1 more source

When the Scale Drops: Pathways to Weight Loss in Parkinson's Disease and Future Directions

Movement Disorders, EarlyView.
Abstract Although Parkinson's disease (PD) is classically defined by its motor features, non‐motor symptoms exert a substantial and often under‐recognized influence on disease trajectory. Among these, weight loss has long been observed in PD and other neurodegenerative disorders, yet the mechanisms remain incompletely understood.
Ellie D. Gabriel, Robert S. Eisinger, Joyce M. Lee, Sarah Hamimi, Hope Kim, Susanna D. Howard, Casey H. Halpern   +6 more
wiley   +1 more source