Results 21 to 30 of about 21,502,425 (295)
IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells [PDF]
, 2012 The cysteine-type peptidase cathepsin X is highly upregulated in several cancers and presumably promotes tumor invasion through bypassing cellular senescence. Here, we present first evidence that the underlying mechanism may involve the regulation of the
Kraus, Steffen +3 more
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Journal of Immunology Research, 2021 Leishmaniases are diseases caused by several Leishmania species, and many factors contribute to the development of the infection. Because the adaptive immune response does not fully explain the outcome of Leishmania infection and considering that the ...
Luiza C. Reis +7 more
doaj +1 more source
Knochenalterassozierte IGF-I und IGFBP-3 Befunde [PDF]
, 2008 Ziel der Arbeit war es aus einem Kollektiv kleinwüchsiger, entwicklungsverzögerter, präpubertärer und sonst gesunder, nicht hGH defizienter Kinder, IGF-I und IGFBP-3 Werte zu sammeln, diese auf das chronologische Alter zu beziehen und mit bereits ...
Grosse, Christina Maria
core +1 more source
Little effects of Insulin-like Growth Factor-I on testicular atrophy induced by hypoxia
BMC Urology, 2006 Background Insulin-like Growth Factor-I (IGF-I) supplementation restores testicular atrophy associated with advanced liver cirrhosis that is a condition of IGF-I deficiency.
Casares Amelia +8 more
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Zmiany w stężeniach insulinopodobnych czynników wzrostu IGF-1 i IGF-2 i białek wiążących BP-2 i BP-3 w czasie leczenia ostrej białaczki limfoblastycznej [PDF]
Pediatric Endocrinology, Diabetes and Metabolism, 2004 Cel pracy: Ocena dynamiki zmian w wartościach insulinopodobnych czynników wzrostu: IGF-1 i IGF-2 i białek wiążących: IGFBP-2 i IGFBP-3 w surowicy krwi dzieci z ostrą białaczką limfoblastyczną (ALL) w trakcie leczenia przeciwnowotworowego.
Maryna Krawczuk-Rybak +2 more
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Frontiers in Endocrinology, 2013 Insulin and the insulin-like growth factors (IGF)-I and –II are closely related peptides important for regulation of metabolism, growth, differentiation and development. The IGFs exert their main effects through the IGF-I receptor.
Soetkin eVersteyhe +7 more
doaj +1 more source
Long-term IGF-I exposure decreases autophagy and cell viability. [PDF]
PLoS ONE, 2010 A reduction in IGF-I signaling has been found to increase lifespan in multiple organisms despite the fact that IGF-I is a trophic factor for many cell types and has been found to have protective effects against multiple forms of damage in acute settings.
Alessandro Bitto +11 more
doaj +1 more source
Associations of insulin and insulin-like growth factors with physical performance in old age in the boyd orr and caerphilly studies. [PDF]
, 2012 OBJECTIVE: Insulin and the insulin-like growth factor (IGF) system regulate growth and are involved in determining muscle mass, strength and body composition.
Gallacher, J +7 more
core +5 more sources
Endocrine Connections, 2019 Objective: Several studies revealed relations between low or high insulin -like growth factor I (IGF-I) levels and risk of cardiovascular diseases or mortality, whereas the mechanisms be hind these associations are still unknown.
Maximilian Eichner +7 more
doaj +1 more source
Biology, 2022 Insulin-like growth factor-1 (IGF-1) plays a crucial role during folliculogenesis, which has been demonstrated by previous research. However, the optimal IGF-1 dosage in the three-dimensional (3D) culture system is unknown. Mouse secondary follicles (140–
Shizhen Dai +4 more
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