Results 61 to 70 of about 152,806 (342)

The role of the IGF axis in IGFBP-1 and IGF-I induced renal enlargement in Snell dwarf mice [PDF]

, 2001
Insulin-like growth factor (IGF) binding protein-1 (IGFBP-1) is generally believed to inhibit IGF action in the circulation. In contrast, IGFBP-1 has been reported to interact with cell surfaces and enhance IGF-I action locally in some ...
Buul-Offers, S.C. van, Drop, S.L.S. (Stenvert), Flyvbjerg, A. (Allan), Kleffens, M. (Marjolein) van, Koster, J.G., Lindenbergh-Kortleve, D.J. (Dicky), Neck, J.W. (Han) van, Rasch, R.   +7 more
core   +2 more sources

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

Wirkung und Wirkungsweise von Insulin-like Growth-factor-I auf das proliferative Wachstum neuroendokriner Tumorzellen am Beispiel der humanen Karzinoidzelllinie BON [PDF]

, 2004
Karzinoide sind neuroendokrine Tumoren des gastroenteropankreatischen Systems. Bis heute gibt es mit Ausnahme eines chirurgischen Eingriffes keine adäquate kurativeTherapiemöglichkeit.
Fehmann, H.-C. (Prof. Dr. med.), Pircher, Benedikt Johannes   +1 more
core   +1 more source

PENAMBAHAN PROTEIN INSULIN LIKE GROWTH FACTOR-I COMPLEX DALAM PENGENCER PEMBEKUAN SEMEN TERHADAP KUALITAS SPERMATOZOA KAMBING PADA WAKTU EKUILIBRASI

Jurnal Kedokteran Hewan, 2011
Penelitian ini bertujuan mengisolasi protein Insulin Like Growth Factor-I (IGF-I) complex untuk meningkatkan kualitas semen beku kambing pada waktu ekuilibrasi setelah penambahan protein IGF-I complex.
Suherni Susilowati, Tatik Hernawati
doaj   +1 more source

TRANSFER OF PLASMA IGF-I INTO LYMPH [PDF]

, 1989
Publisher Summary This chapter elaborates the transfer of plasma IGF-I into lymph. In vitro experiments suggest free unbound IGF-I can be transferred intact across the capillary endothelium. It is found that however, in the intact animal 95% or more of the circulating IGF-I is bound to specific high molecular weight binding proteins which are thought ...
Baucells Sánchez, María Dolores, Fleet, I.R., Prosser, C.G.   +2 more
openaire   +3 more sources

3D Bioprinted Renal Constructs Using Kidney‐Specific ECM Bioink System on Kidney Regeneration

Advanced Healthcare Materials, EarlyView.
A kidney‐specific bioink derived from decellularized porcine kidney tissue supports the encapsulation, viability, and maturation of human primary kidney cells within 3D bioprinted constructs. In vivo, it also promotes the recruitment of host renal progenitor cells, collectively enhancing structural and functional regeneration of renal tissue.
Gabriel Carreno‐Galeano, Mohamed Ali, James J. Yoo, Sang Jin Lee, Anthony Atala   +4 more
wiley   +1 more source

Gene polymorphisms in primary biliary cirrhosis: association with the disease and hepatic osteopathy [PDF]

, 2007
Genetic factors have been implicated in the pathogenesis of osteoporosis, a common disorder in primary biliary cirrhosis (PBC). Estrogen receptor-alpha gene (ER- ), vitamin-D-receptor gene (VDR) and IL-1-receptor-antagonist gene (IL-1RN) are all ...
Bajnok, Éva, Ferenci, Péter, Lakatos, Péter, Lakatos, Péter László, Szalay, Ferenc, Takács, István, Willheim-Polli, Claudia   +6 more
core  

Aspects of Growth Hormone and Insulin-Like Growth Factor-I Related to Neuroprotection, Regeneration, and Functional Plasticity in the Adult Brain

The Scientific World Journal, 2006
Apart from regulating somatic growth and metabolic processes, accumulating evidence suggests that the growth hormone (GH)/insulin-like growth factor-I (IGF-I) axis is involved in the regulation of brain growth, development, and myelination.
N. David Åberg, Katarina Gustafson Brywe, Jörgen Isgaard   +2 more
doaj   +1 more source

Hepatic mRNA expression and plasma levels of insulin-like growth factor-I (IGF-I) in broiler chickens selected for different growth rates

Genetics and Molecular Biology, 2004
The hepatic expression and plasma concentrations of IGF-I were investigated in three broiler chicken strains selected for different growth rates (HP-Hubbard-Pettersen, a fast growing strain; NN-Naked-neck, a strain with an intermediate growth rate and a ...
Poliana Fernanda Giachetto, Eduardo Correa Riedel, Jane Eyre Gabriel, Maria Inês Tiraboschi Ferro, Sônia Marli Zingaretti Di Mauro, Marcos Macari, Jesus Aparecido Ferro   +6 more
doaj   +1 more source

Toward a comprehensive neurobiology of IGF‐I [PDF]

Developmental Neurobiology, 2010
AbstractInsulin‐like growth factor I (IGF‐I) belongs to an ancient family of hormones already present in early invertebrates. The insulin family is well characterized in mammals, although new members have been described recently. Since its characterization over 50 years ago, IGF‐I has been considered a peptide mostly involved in the control of body ...
openaire   +4 more sources