Results 151 to 160 of about 87,101 (260)

High‐Content Screening Comparison of 1R6F Cigarette Smoke Extract and Selected Heated Tobacco and Electronic Vapour Product Aerosol Extracts in Endothelial and Bronchial Epithelial Cell Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Cigarettes induce oxidative stress and DNA damage, processes that contribute to cardiovascular and pulmonary disease. High content screening (HCS) is an increasingly valuable tool for comparative toxicology because it enables simultaneous quantification of multiple mechanistic endpoints at single‐cell resolution. In this study, HCS was used to
Edgar Trelles Sticken, Konstantinos Papikinos, Fiona Chapman, Roman Wieczorek, Sarah Jean Pour, Torge Evenburg, Sandra Otte, Tiandan Wu, Liam Simms, Matthew Stevenson   +9 more
wiley   +1 more source

Correction: Kingshott et al. Alteration of Metabolic Conditions Impacts the Regulation of IGF-II/H19 Imprinting Status in Prostate Cancer. Cancers 2021, 13, 825. [PDF]

Cancers (Basel)
Kingshott G, Biernacka K, Sewell A, Gwiti P, Barker R, Zielinska H, Gilkes A, McCarthy K, Martin RM, Lane JA, McGeagh L, Koupparis A, Rowe E, Oxley J, Holly JMP, Perks CM.   +15 more
europepmc   +1 more source

First‐Trimester Crown‐Rump Length and Large for Gestational Age Newborns: What Correlation?

Journal of Clinical Ultrasound, EarlyView.
Our research found for the first time that uneventful pregnancies with LGA neonates are characterized by larger than expected CRL at the first trimester. CRL is one of the new markers that can be used to early identify fetuses at risk of increased fetal growth.
Marika Ylenia Rovetto, Laura Sarno, Giuseppe Gabriele Iorio, Giuliana Orlandi, Caterina Fulgione, Mariarosaria Motta, Anna Luna Tramontano, Giuseppe Rizzo, Ilenia Mappa, Maurizio Guida, Giuseppe Maria Maruotti   +10 more
wiley   +1 more source

Nutritional and environmental determinants of maturation and disruption of the early life gut microbiome: A narrative review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The first 1000 days of life represent a critical window for gut microbiome assembly, with lifelong implications for child growth, immune development, and disease risk. This review synthesizes evidence on maternal, perinatal, and especially nutritional factors that influence early‐life intestinal colonization and highlights the consequences of ...
Carly Burow, Romy Shenderey, Fariha Chowdhury, Nyah Shah, Nikhil Pai   +4 more
wiley   +1 more source

IGFBP-2 and IGF-II: Key Components of the Neural Stem Cell Niche? Implications for Glioblastoma Pathogenesis. [PDF]

Int J Mol Sci
Harland AJ, Perks CM.
europepmc   +1 more source

Investigating the Relationship Between IGF-I, IGF-II, and IGFBP-3 Concentrations and Later-Life Cognition and Brain Volume.

J Clin Endocrinol Metab, 2021
Salzmann A, James SN, Williams DM, Richards M, Cadar D, Schott JM, Coath W, Sudre CH, Chaturvedi N, Garfield V.   +9 more
europepmc   +1 more source

Twenty‐four month clinical outcomes of modified coronally advanced tunnel technique with leukocyte‐ and platelet‐rich fibrin–functionalized porcine dermal matrix for single/multiple gingival recessions

Journal of Periodontology, EarlyView.
Abstract Background To report 24‐month clinical and 3D outcomes of single and multiple RT1 and RT2 gingival recessions treated with the modified coronally advanced tunnel (MCAT) technique and an L‐PRF‐functionalized porcine dermal matrix (PDM), as long‐term data on PDM in root coverage are scarce.
Erik Würflein, Katharina Herrmann, Anton Sculean, Kirstin Vach, Katja Nelson, Tobias Fretwurst, Gerhard Iglhaut, Florian Kernen   +7 more
wiley   +1 more source

An in vitro comparison of PDGF‐BB release from composite graft materials containing leukocyte‐rich platelet‐rich fibrin and platelet‐derived growth factor‐BB and β‐tricalcium phosphate

Journal of Periodontology, EarlyView.
Abstract Background The clinical efficacy of growth factors in regenerative procedures may depend on both dosage and sustained delivery during critical phases of healing. This study aimed to evaluate in vitro release kinetics of platelet‐derived growth factor‐BB (PDGF‐BB) from various graft materials, including recombinant human PDGF‐BB (rhPDGF‐BB ...
Farahnaz Fahimipour, Maggie A. Misch‐Haring, Ramzi V. Abou Arraj, Nicolaas C. Geurs, Maria L. Geisinger   +4 more
wiley   +1 more source

Tumor-associated macrophages promote human hepatoma Huh-7 cell migration and invasion through the Gli2/IGF-II/ERK1/2 axis by secreting TGF-β1. [PDF]

Cancer Biol Ther, 2020
Liu M, Zhong YB, Shao J, Zhang C, Shi C.
europepmc   +1 more source

The effect of leukocyte–platelet‐rich fibrin in periodontal surgery on clinical parameters and patient‐related outcome measures: A randomized, controlled, clinical study

Journal of Periodontology, EarlyView.
Abstract Background This prospective study aimed to assess the clinical outcomes and patient‐related outcome measures (PROMs) of open flap debridement (OFD) alone versus open flap debridement with leukocyte–platelet‐rich fibrin (L‐PRF). Methods Twenty‐one patients were enrolled into a split‐mouth randomized clinical trial.
Jackson S. Sides, Archontia Palaiologou, Brian L. Mealey, Stephan J. Haney, Kerri Font, Charles A. Powell   +5 more
wiley   +1 more source