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Vaginal dysbiosis and inflammatory signatures in preterm labor: an integrated model for predicting preterm birth. [PDF]
Hong S +9 more
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Clinical Presentation and Outcomes of Insulinomas in Pediatric Patients.
Mitteer LM +9 more
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Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer
European Journal of Cancer, 2005Insulin and insulin-like growth factors (IGFs) have critical functions in growth regulatory signalling pathways. They are part of a tightly controlled network of ligands, receptors, binding proteins and their proteases. However, the system becomes uncontrolled in neoplasia. The insulin-like growth factor binding protein 3 (IGFBP-3) and the insulin-like
Arun Seth +2 more
exaly +3 more sources
Localization studies of IGFBP-2 and IGFBP-5 in the anterior compartment of the eye
Insulin-like growth factor binding proteins (IGFBPs) may modulate insulin-like growth factor-I (IGF-I) action and are important regulating factors in the IGF system. Our aim was to determine the presence of IGFBP-2 and -5 in the anterior compartment of the eye and to compare the histological sites of these IGFBP proteins with the respective IGFBP mRNAs.
Burren, Christine P. +2 more
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Regulation of IGFBP-1 in humans
Progress in Growth Factor Research, 1995IGFBP-1 secretion in humans is regulated by insulin and the counter-regulatory hormones with a high production rate and rapid turnover. The IGFBP-1 fasting levels are both genetically and environmentally determined. Serum IGFBP-1 levels may be regulated by so far unknown factors during certain conditions.
Kerstin Brismar, Agneta Hilding
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Up date on IGFBP-4: regulation of IGFBP-4 levels and functions, in vitro and in vivo
Growth Hormone and IGF Research, 2004Of the six known high affinity insulin-like growth factor binding-proteins (IGFBPs), IGFBP-4 appears to be unique in that it is the only IGFBP that functions mostly like a traditional binding protein. In this regard, none of the IGF independent effects that have been ascribed for other IGFBPs have been described for IGFBP-4.
Sabine Mazerbourg +2 more
exaly +5 more sources
Best Practice & Research Clinical Endocrinology & Metabolism, 2015
Andreas Hoeflich, Vincenzo C Russo
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Andreas Hoeflich, Vincenzo C Russo
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IGFBP-2: The dark horse in metabolism and cancer
Cytokine and Growth Factor Reviews, 2015Matthew A. Sabin, V C Russo, G A Werther
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THE ROLE OF IGFBP-3 IN THE REGULATION OF IGFBP-4 PROTEOLYSIS
Journal of Endocrinology, 1996ABSTRACT The biological effects of insulin-like growth factors (IGFs) are mediated by cell surface receptors but their bioavailability is regulated by IGF binding proteins (IGFBPs) which bind IGF with higher affinity than the receptor.
M J, Donnelly, J M, Holly
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