Results 91 to 100 of about 232,932 (206)

IgG4-related disease : why high IgG4 and fibrosis? [PDF]

, 2013
The hallmarks of IgG4-related disease (IgG4-RD) are lymphoplasmacytic tissue infiltration with a predominance of IgG4-positive plasma cells, accompanied by fibrosis, obliterative phlebitis, dacryoadenitis, and elevated levels of IgG4.
Koike, Takao
core   +1 more source

Clinical Images: Features of IgG4‐related disease in a patient with granulomatosis with polyangiitis

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Florian Kollert, David R. Bisharat, Velina Widmer, Bernhard Hausenberger, Simona Negoias, Ingmar Heijnen, Alexandar Tzankov, Kirsten Mertz, Diego Kyburz, Thomas Daikeler   +9 more
wiley   +1 more source

TGF‐β1‐driven epithelial‒mesenchymal transition mediates the fibrotic process in IgG4‐related disease

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
In IgG4‐related disease, the epithelial‐to‐mesenchymal transition of fibroblasts was predominantly driven by transforming growth factor‐β1 secreted from CD19+ B cells. Reciprocally, fibroblasts facilitated CD19+ B‐cell survival and activation through CXCL14–CXCR4 and CXCL12–CXCR4 signalling axes, thereby promoting B‐cell responses and subsequent ...
In‐Woon Baek, Kyung‐Su Park, Ki‐Jo Kim   +2 more
wiley   +1 more source

MOESM4 of Identifying clinical subgroups in IgG4-related disease patients using cluster analysis and IgG4-RD composite score

, 2020
Additional file 4. Other differences among Clusters. a, Distribution of the grades of complement in clusters. Normal values of C3 and C4 were 0.73-1.46 and 0.1-0.4(g/L), respectively. b, Distribution of the grades of IgG4-RD CS in clusters. (CS1, range-1.
Liang Zhu (172992), Huadan Xue (487099), Jieqiong Li (327149), Yu Peng (144570), Zheng Liu (28397), Panpan Zhang (534098), Hui Lu (12370), Xiaofeng Zeng (309980), Yunyun Fei (4966966), Yuelun Zhang (684678), Yan Zhao (58882), Wen Zhang (7555), Linyi Peng (4966969)   +12 more
core   +1 more source

AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén, Lucía Guilabert, Emma Martínez‐Moneo, Carla Mancilla, Miguel Bispo, Pedro Moutinho‐Ribeiro, Rodrigo Mansilla, Andreia Rei, Ana García García de Paredes, Antonio López‐Serrano, Bruno Rosa, Claudia Sánchez‐Marín, Daniel de la Iglesia, Edson Guzmán‐Calderon, Eduardo Rodrigues‐Pinto, Eva Marín‐Serrano, Fabio Ausania, Fauze Maluf‐Filho, Guido Villagómez, Humberto Cristino, Isabel Pascual‐Moreno, José A. Gonzalez, José M. Ramia, João Lopes‐Delgado, Lucas Granero, Mario Peláez‐Luna, María Francisco, Natalia Corzo‐Zamora, Ricardo Rio‐Tinto, Rómulo D. Vargas, Sandra Basso, Susana Lopes, Susana Marques, William Manzanares, Zoltán Berger, Irene Carrillo, José Joaquín Mira‐Solves, Alberto Espino, Adriana Cowdin, Alejandro Piscoya, Alexandra Fernandes, Noelia Rodríguez‐Ferreiro, Neftalí Jara Pérez‐López, Beatriz Valero, Enrique de‐Madaria   +44 more
wiley   +1 more source

IgG4-related disease-like lesion arising within a well-differentiated liposarcoma/an atypical lipomatous tumor: two cases report

Frontiers in Oncology
IntroductionWell-differentiated liposarcoma (WDLPS) is a locally aggressive soft tissue sarcoma characterized by the amplification of MDM2 and/or CDK4.
Naoki Oike, Tomoaki Torigoe, Akira Ogose, Akira Ogose, Takashi Ariizumi, Tomohiro Miyazaki, Yudai Murayama, Taku Homma, Hajime Umezu, Takuya Watanabe, Hiroyuki Kawashima   +10 more
doaj   +1 more source

Single-cell transcriptome analysis and protein profiling reveal broad immune system activation in IgG4-related disease

JCI Insight, 2023
IgG4-related disease (IgG4-RD) is a systemic autoimmune disease with unclear pathogenesis. We performed single-cell RNA-seq and surface proteome analyses on 61,379 PBMCs from 9 treatment-naive IgG4-RD patients and 7 age- and sex-matched healthy controls.
Chenyang Lu, Shasha Li, Pingying Qing, Qiuping Zhang, Xing Ji, Zhigang Tang, Chunyan Chen, Tong Wu, Yidan Hu, Yi Zhao, Xiaohui Zhang, Qi He, David A. Fox, Chunyu Tan, Yubin Luo, Yi Liu   +15 more
doaj   +1 more source

Deciphering the full spectrum of Castleman diseases based on a cohort of 700 patients in a western country

British Journal of Haematology, Volume 208, Issue 6, Page 2036-2046, June 2026.
The spectrum of Castleman diseases has expanded over the past three decades. The phenotype of the diseases varies not only among the three major types but also according to the patient ancestry. Summary Under the Castleman disease (CD) eponym, three distinct diseases sharing common pathological features have been described over time.
Eric Oksenhendler, Marion Malphettes, Véronique Meignin, David Boutboul, Lionel Galicier   +4 more
wiley   +1 more source

Profiles of IgG4-RD patients analyzed by DNA microarrays.

, 2015
Patients were diagnosed according to the comprehensive diagnostic criteria for IgG4-RD [6] and were subsequently treated with steroids. IgG(mg/dL), IgG4(mg/dL), IgE(IU/mL).
Motohisa Yamamoto (739148), Shintaro Hirata (739150), Haruka Iwao (301252), Yoshimasa Fujita (301256), Shoko Matsui (739144), Norifumi Tsukamoto (491191), Hisanori Morimoto (739152), Hisanori Umehara (301265), Tomoyuki Sakai (301250), Kazuichi Okazaki (455910), Takuji Nakamura (301254), Hiroto Tsuboi (739151), Takayuki Sumida (12557), Toshihiro Fukushima (301258), Mitsuhiro Kawano (739143), Tomomi Sato (301255), Yasufumi Masaki (301257), Terumi Kamisawa (739146), Kazunori Yamada (286428), Hideaki Hamano (272469), Masao Tanaka (107633), Akio Nakajima (301253), Miyuki Miki (301251), Keita Fujikawa (398060), Takafumi Kawanami (301248), Tomoki Origuchi (739149), Tsutomu Takegami (178954), Takako Saeki (739145), Yoshihiro Yakushijin (739147), Toshiro Okazaki (301263), Yasuhito Ishigaki (178926), Taiichiro Miyashita (290199)   +31 more
core   +1 more source

[18F]FAPI PET/CT-based scoring systems for patient assessment in IgG4-related disease

RMD Open
Background 18F-Fibroblast activation protein inhibitor ([18F]FAPI) positron emission tomography (PET)/CT is an emerging tool for detecting IgG4-related disease (IgG4-RD).
Zhenfeng Liu, Kui Zhao, Danqing Huang, Chuanyin Sun, Donghe Chen, Danhua Zhu, Xinhui Su   +6 more
doaj   +1 more source