Results 71 to 80 of about 232,932 (206)
Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease
BackgroundThe IgG4-related disease (IgG4-RD) is an immune-mediated disorder with fibrotic manifestations. However, the transcriptional profiles of immune cell subsets at single-cell level are unknown. Herein, single-cell sequencing was used to assess the
Xunyao Wu +12 more
doaj +1 more source
IgG4-related disease (IgG4-RD) – auch eine Erkrankung des Kindesalters
ZusammenfassungIgG4-related disease (IgG4-RD) ist eine neu beschriebene entzündlich fibrosierende Erkrankung unklarer Ätiologie, die eine Vielzahl von Organen befallen kann.
M. Hufnagel +2 more
core +1 more source
Objective Immunoglobulin G4‐related disease (IgG4‐RD) is a systemic immune‐mediated fibroinflammatory condition. Previous studies have indicated relationships between malignancy and autoimmunity. This retrospective cohort study aimed to determine IgG4‐RD
Diping Hu +8 more
doaj +1 more source
Severe Aortic Valvular Incompetence From IgG4-Related Disease
IgG4-related disease (IgG4-RD) is a new clinical entity characterized by lymphoplasmacytic lesions rich in IgG4-positive plasma cells. Myocardial involvement is extremely rare and not a typical cardiovascular manifestation of IgG4-RD.
Bing Wei Thaddeus Soh, MB +8 more
doaj +1 more source
Nucleotide Metabolism in Health and Disease
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source
Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4 [PDF]
Schistosoma haematobium antigen recognition profiles of the human isotypes IgA, IgE, IgG1 and IgG4 were compared by image analysis of western blots. Adult worm antigens separated by 2-dimensional gel electrophoresis were probed with pooled sera from ...
Midzi, N. +28 more
core +1 more source
Clinical Characteristics of Patients With IgG4-Related Disease Complicated by Hypocomplementemia
BackgroundA proportion of patients with immunogloblin G (IgG) 4-related disease (IgG4-RD) have hypocomplementemia. We aimed to identify characteristics of such patients.MethodsWe analyzed the demographic and clinical data and complement levels of 85 ...
Yuya Fujita +16 more
doaj +1 more source
ABSTRACT Background IgG4‐related disease (IgG4‐RD) is a systemic, immune‐mediated, fibroinflammatory disorder with multiorgan involvement and variable clinical presentation, often creating diagnostic difficulty. Myasthenia gravis (MG) is an antibody‐mediated autoimmune disorder of the neuromuscular junction, most commonly associated with anti ...
Yumiko Yoshida +4 more
wiley +1 more source
ABSTRACT Aims Despite the recommendation of steroid therapy for type 1 autoimmune pancreatitis (AIP), the value of steroid pulse therapy remains unclear. This study aimed to assess the efficacy and safety of steroid pulse therapy in patients with AIP. Methods and Results Of 121 patients with type 1 AIP who were identified, 116 with adequate follow‐up ...
Akihisa Adachi +11 more
wiley +1 more source

