Results 61 to 70 of about 232,932 (206)

IgG4-related disease in patients with newly diagnosed idiopathic retroperitoneal fibrosis: a population-based Danish study

, 2019
Objectives: IgG4-related disease (IgG4-RD) may present as ‘idiopathic’ retroperitoneal fibrosis (IRPF). We aimed to determine the occurrence of IgG4-retroperitoneal fibrosis (IgG4-RPF) in a nationwide study on patients with newly diagnosed IRPF, and to ...
N Lomborg (6531722), CS Bode (6531728), M Jakobsen (6531725), P Junker (3104853)   +3 more
core   +1 more source

IgG4-related disease (IgG4-RD) in developmental age — diagnostic and therapeutic problems [PDF]

, 2019
The IgG4-related disease (IgG4-RD) is a type of a Hypergammaglobulinemia with elevated class IgG4 of unknown aetiology. It is still rarely diagnosed due to lack of clear diagnostic criteria and uncertain ethiopathogenesis.
Żuber, Zbigniew; Department of Paediatrics, Andrzej Frycz-Modrzewski Krakow University, Clinical Department of Rheumatology, Paediatrics and Allergology, St. Louis Children’s Hospital in Krakow, Kraków, Poland; Katedra Pediatrii KA AFM Kraków, G. Herlinga-Grudzińskiego 1, 30-750 Kraków, Poland, Orlicka, Justyna; Department of Paediatrics, Andrzej Frycz-Modrzewski Krakow University, Clinical Department of Rheumatology, Paediatrics and Allergology, St. Louis Children’s Hospital in Krakow, Kraków, Poland, Turowska-Heydel, Dorota; Department of Paediatrics, Andrzej Frycz-Modrzewski Krakow University, Clinical Department of Rheumatology, Paediatrics and Allergology, St. Louis Children’s Hospital in Krakow, Kraków, Poland   +2 more
core   +1 more source

High-throughput sequencing of CD4+ T cell repertoire reveals disease-specific signatures in IgG4-related disease

Arthritis Research & Therapy, 2019
Background CD4+ T cells play critical roles in the pathogenesis of IgG4-related disease (IgG4-RD). The aim of this study was to investigate the TCR repertoire of peripheral blood CD4+ T cells in IgG4-RD.
Liwen Wang, Panpan Zhang, Jieqiong Li, Hui Lu, Linyi Peng, Jing Ling, Xuan Zhang, Xiaofeng Zeng, Yan Zhao, Wen Zhang   +9 more
doaj   +1 more source

Clinical characteristics of a concurrent condition of IgG4-RD and Castleman’s disease [PDF]

Clinical Rheumatology, 2018
IgG4-related disease (IgG4-RD) and Castleman's disease (CD) share similar clinical manifestations. When the histopathology coincides with the diagnosis of both IgG4-RD and CD, it is hard to depart the two disease entities utterly; here we call it IgG4-CD provisionally. In this study, we aim to review the clinical features of IgG4-CD.
Xia, Zhang, Panpan, Zhang, Linyi, Peng, Yunyun, Fei, Wei, Zhang, Ruie, Feng, Wen, Zhang   +6 more
openaire   +2 more sources

CXCL12/SDF-1 in IgG4-Related Disease

Frontiers in Pharmacology, 2021
Background: SDF-1/CXCL12 is a chemokine with pleiotropic functions in hematopoietic stem cell niche homeostasis, germinal center architecture, B cell maturation, neoangiogenesis, and fibrosis.
Riccardo Capecchi, Cristina Croia, Ilaria Puxeddu, Federico Pratesi, Andrea Cacciato, Daniela Campani, Ugo Boggi, Luca Morelli, Antonio Tavoni, Paola Migliorini   +9 more
doaj   +1 more source

Sinonasal IgG4-RD: Case Report and Systematic Review [PDF]

, 2021
Immunoglobin G4 – related disease (IgG4-RD) is a chronic fibro-inflammatory condition that presents as a single or multiple tumefactive lesions affecting virtually any organ system. Here we report a case of recurrent sinonasal IgG4-RD and review the literature of this evolving entity.
Caleb Wilson, Benjamin Brownlee, Edward El Rassi, Kibwei McKinney   +3 more
openaire   +1 more source

Real‐World Efficacy and Systemic Immune Modulation Upon Tralokinumab Treatment in Atopic Dermatitis

Clinical and Translational Allergy, Volume 16, Issue 9, September 2026.
ABSTRACT Background Tralokinumab, an interleukin‐13 (IL‐13) monoclonal antibody, has shown clinical efficacy in randomized trials for moderate‐to‐severe atopic dermatitis (AD). This study aims to evaluate clinical and immunological outcome upon tralokinumab treatment in a real‐world cohort of patients with moderate‐to‐severe AD. Methods We recruited 81
Meslina Almaci, Philipp Globig, Davender Redhu, Margitta Worm   +3 more
wiley   +1 more source

Differential CpG DNA methylation of peripheral B cells, CD4+ T cells, and salivary gland tissues in IgG4-related disease

Arthritis Research & Therapy, 2023
Objectives Immunoglobulin-G4-related disease (IgG4-RD) is a distinct systemic autoimmune-mediated disease manifesting as chronic inflammation and tissue fibrosis.
Xunyao Wu, Anqi Wang, Mu Wang, Yu Peng, Yingying Chen, Jieqiong Li, Zheng Liu, Hui Lu, Jiaxin Zhou, Linyi Peng, Yan Zhao, Xiaofeng Zeng, Yunyun Fei, Wen Zhang   +13 more
doaj   +1 more source

Identification of Discriminatory Factors and Construction of a Nomogram for Differentiating IgG4‐RD and DLBCL

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Objective To determine clinically useful indicators that distinguish IgG4‐related disease (IgG4‐RD) from diffuse large B‐cell lymphoma (DLBCL) and to construct a predictive model that may assist early identification. Methods We retrospectively analyzed 19 patients with IgG4‐RD and 37 with DLBCL who presented with lymphadenopathy and received ...
Yongkang Chen, Weimiao Li, Zhou Zhou, Jiqing Wu, Dongmei Zhou   +4 more
wiley   +1 more source

Serum IgG4 levels (mean values) in IgG4-RD patients before and after treatment (measured by ELISA).

, 2015
A: Numbers 1 to 8 indicate different patients. Serum IgG4 titers of 8 participants with IgG4-RD were compared before and after treatment. The follow-up time was 1 to 14 months.B: A comparison of the mean serum IgG4 levels from 8 IgG4-RD patients before ...
Xuefen Wu (725892), Lingli Dong (6512), Ye Miao (450660), Wei Sun (93580), Lin Bai (338207), Yuying Su (725890), Hui Xiong (541837), Chenqiong Wang (725891)   +7 more
core   +1 more source