Results 51 to 60 of about 48,471 (314)
Human Pathology: Case Reports, 2019 IgG4-related kidney disease (IgG4RKD) generally presents as an active and chronic fibrosing tubulointerstitial nephritis. Recent reports have described glomerular lesions, typically with IgG4 containing subepithelial/membranous deposits as part of ...
Joichi Usui +5 more
doaj +1 more source
IgG4-related autoimmune disease : imaging findings [PDF]
, 2013 IgG4 autoimmune disease (or hyper IgG4 disease) is a relatively recently described systemic disease that is characterised by abundant infiltration of IgG4-positive plasma cells and lymphocytes with associated fibrosis leading to organ dysfunction ...
Vassallo, Pierre
core
Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study [PDF]
, 2018 Glucocorticoids (GC) are effective for treating IgG4-related disease (IgG4-RD); however, relapse is often observed. We conducted a retrospective multicentre study to investigate risk factors in GC regimens associated with relapses of IgG4-RD. Data on 166
Chiba Tsutomu +26 more
core +2 more sources
IgG4-related sclerosing disease
World Journal of Gastroenterology, 2008 Based on histological and immunohistochemical examination of various organs of patients with autoimmune pancreatitis (AIP), a novel clinicopathological entity of IgG4-related sclerosing disease has been proposed. This is a systemic disease that is characterized by extensive IgG4-positive plasma cells and T-lymphocyte infiltration of various organs ...
Terumi, Kamisawa, Atsutake, Okamoto
openaire +2 more sources
Advanced Science, EarlyView.This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma +10 more
wiley +1 more source
Malignancies and IgG4‐related disease
Rheumatology & AutoimmunityImmunoglobulin G4‐related disease (IgG4‐RD) is a systemic fibro‐inflammatory disease characterized by tumefactive lesions. Beyond the role of the disease as a cancer mimic, studies over the past decade have demonstrated that IgG4‐RD is associated with ...
Jingna Li, Wen Zhang
doaj +1 more source
F1000Research, 2023 Immunoglobulin G4 (IgG4)-related disease is a systemic inflammatory disorder characterized by tubulointerstitial nephritis with IgG4-positive plasma cell infiltration.
Akira Mima +5 more
doaj +1 more source
The future outlook on allergen immunotherapy in children: 2018 and beyond. [PDF]
, 2018 Allergen immunotherapy (AIT) is the only currently available immune-modifying and aetiological treatment for patients suffering from IgE-mediated diseases.
Arasi S, Corsello G, Pajno GB, Villani A
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T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Immunoglobulin G4-Related Disease Mimicking Asthma
Canadian Respiratory Journal, 2013 Immunoglobulin (Ig) G4-related disease (also known as ‘IgG4-related sclerosing disease’, ‘IgG4-related systemic disease’ or ‘hyper-IgG4-disease’) is a recently recognized systemic fibroinflammatory disease associated with IgG4-positive plasma cells in ...
Hiroshi Sekiguchi +4 more
doaj +1 more source