Renal Involvement in IgG4-Related Disease: From Sunlight to Twilight
IgG4-Related Disease (IgG4-RD) is a fibroinflammatory condition characterized by a typical histopathological pattern (dense lymphoplasmacytic infiltrate with prevalent IgG4+ plasma cells and storiform fibrosis), which may involve the kidney both directly
Riccardo Capecchi +10 more
doaj +1 more source
Serum BAFF and APRIL levels in patients with IgG4-related disease and their clinical significance. [PDF]
[Introduction]B cell-activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL) play a crucial role in B cell development, survival, and antibody production.
Fujii, Takao +8 more
core +2 more sources
IgG4-related disease (RD) is characterized by lymphoplasmacytic infiltration enriched in IgG4-positive plasma cells and variable degrees of fibrosis with a characteristic storiform pattern.
Yaping Luo +5 more
semanticscholar +1 more source
Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma [PDF]
Background: Sublingual allergen immunotherapy (SLIT) has been demonstrated to be both clinically efficacious and safe. However, in line with the current regulatory guidance from the European Medicines Agency, allergen immunotherapy (AIT) products must ...
Bachert, Claus +10 more
core +2 more sources
Clinical and pathological predictors of relapse in IgG4-related disease
Objectives In IgG4-related disease, the relationship between pathological findings and relapse has not been well established. This study aimed to identify the clinical and pathological predictors of disease relapse in IgG4-RD. Methods Patients with newly
Z. Ji +10 more
semanticscholar +1 more source
IgG4 Related Cardiac Disease [PDF]
IgG4-related systemic disease is an inflammatory disorder that can affect many organs. This case report describes a patient who in 2004 was found to have an inflammatory pseudotumor with IgG4 pathology. Over the next 3 years, visual symptoms responded well to recurrent courses of prednisone.
Hector, Carbajal +6 more
openaire +2 more sources
IgG4-Related Disease without Overexpression of IgG4: Pathogenesis Implications
IgG4-related disease is a new disease group that affects multiple organs. It is characterized by high serum IgG4 and abundant infiltration of IgG4-bearing plasma cells in the affected organ.
Naoshi Nishina +6 more
doaj +1 more source
Serum IgG2 levels are specifically associated with whole-body insulin-mediated glucose disposal in non-diabetic offspring of type 2 diabetic individuals. a cross-sectional study [PDF]
.Preclinical studies suggested that IgG2c isotype may specifically impair skeletal muscle insulin sensitivity in mice. In this study we investigated the association between serum levels of the four IgG subclasses and insulin sensitivity in non-diabetic
Andreozzi, F +11 more
core +2 more sources
Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease
Background The IgG4-related disease (IgG4-RD) is an immune-mediated disorder with fibrotic manifestations. However, the transcriptional profiles of immune cell subsets at single-cell level are unknown.
Xunyao Wu +11 more
semanticscholar +1 more source
IgG4-related Breast Disease: Review of the Literature
IgG4-related disease (IgG4-RD) is a rare illness with inflammatory and fibrotic changes in affected organs such as pancreas, thyroid, salivary or lacrimal glands, and retroperitoneal space; rarely other organs may be involved. IgG4-related breast disease
Helana Jeries +2 more
doaj +1 more source

