Results 11 to 20 of about 46,091 (305)

IgG4 autoantibodies and autoantigens in the context of IgG4-autoimmune disease and IgG4-related disease [PDF]

Frontiers in Immunology
Immunoglobulins are an essential part of the humoral immune response. IgG4 antibodies are the least prevalent subclass and have unique structural and functional properties. In this review, we discuss IgG4 class switch and B cell production. We review the importance of IgG4 antibodies in the context of allergic responses, helminth infections and ...
Rodrigo V. Motta, Emma L. Culver, Emma L. Culver   +2 more
core   +8 more sources

Detection of serum IgG4 levels in patients with IgG4-related disease and other disorders. [PDF]

PLoS ONE, 2015
Elevated serum IgG4 levels are an important hallmark for diagnosing IgG4-related disease (IgG4-RD), but can also be observed in other diseases. This study aimed to compare two different testing methods for IgG4: ELISA and nephelometric assay. Both assays
Yuying Su, Wei Sun, Chenqiong Wang, Xuefen Wu, Ye Miao, Hui Xiong, Lin Bai, Lingli Dong   +7 more
doaj   +2 more sources

Giant IgG4-Related Pseudotumor of the Esophagus Resected with Endoscopic Submucosal Dissection: A Case Report and Review of the Literature

Türk Patoloji Dergisi, 2021
IgG4-related disease (IgG4-RD) is a systemic autoimmune disorder that has been defined in various organs. The disease is characterized by typical clinicopathological features including a dense lymphoplasmacytic infiltrate rich in IgG4 positive plasma ...
Nese EKINCI, Duygu UNAL KOCABEY, Eylul GUN, Fatih ASLAN   +3 more
doaj   +1 more source

IgG4-Related Esophageal Disease Presenting as Esophagitis with Chronic Strictures

GE: Portuguese Journal of Gastroenterology, 2021
IgG4-related disease is a recently recognized autoimmune systemic disorder that has been described in various organs. The disease is characterized histologically by a dense lymphoplasmacytic infiltrate with IgG4-positive cells, storiform fibrosis ...
Catarina Correia, Hélder Moreira, Nuno Almeida, Marta Soares, Augusta Cipriano, Pedro Figueiredo   +5 more
doaj   +1 more source

IgG4-Related Disease [PDF]

International Journal of Rheumatology, 2013
IgG4-related disease (IgG4-RD) is a novel clinical disease entity characterized by an elevated serum IgG4 concentration and tumefaction or tissue infiltration by IgG4-positive plasma cells. IgG4-RD encompasses a wide variety of diseases, formerly diagnosed as Mikulicz's disease (MD), autoimmune pancreatitis (AIP), hypophysitis, Riedel thyroiditis ...
Stone, John H., Chan, John K. C., Deshpande, Vikram, Okazaki, Kazuichi, Umehara, Hisanori, Zen, Yoh   +5 more
openaire   +2 more sources

Childhood IgG4-related orbital disease: A delayed diagnosis

Indian Journal of Ophthalmology. Case Reports, 2022
IgG4-related disease is a multisystem disorder characterized by tumefactive lesions comprising of IgG4-bearing plasma cells with fibrosis. We report a case of pediatric IgG4-related orbital disease that was diagnosed 12 years after its first clinical ...
Rachna Meel, Seema Kashyap, Meenakshi Wadhwani, Mandeep S Bajaj, Sanjay S Sharma   +4 more
doaj   +1 more source

Modern view on the complement system role in membranous nephropathy

Терапевтический архив, 2022
Membranous nephropathy (MN), an immune-mediated glomerular disease, is the most common cause of adult nephrotic syndrome. In MN, proteinuria is developed by podocyte damage due to the complement system activation in response to the subepithelial ...
Elena S. Kamyshova, Tatyana A. Semeryuk, Irina N. Bobkova   +2 more
doaj   +1 more source

Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4 [PDF]

, 2010
Schistosoma haematobium antigen recognition profiles of the human isotypes IgA, IgE, IgG1 and IgG4 were compared by image analysis of western blots. Adult worm antigens separated by 2-dimensional gel electrophoresis were probed with pooled sera from ...
Midzi, N., Maizels, R M, Burchmore, R., Y. HARCUS, Mduluza, T., R. M. MAIZELS, Harcus, Y, Turner, C.M.R., R. BURCHMORE, C. M. TURNER, Mutapi, F, Midzi, N, Mutapi, F., Maizels, R.M., Turner, C M, Maizels, RM, N. MIDZI, Harcus, Y., Bourke, C., F. MUTAPI, T. MDULUZA, Turner, CM, Maizels, R. M., Bourke, C, Turner, C. M., Mduluza, T, Burchmore, R.J.S., Burchmore, R, C. BOURKE   +28 more
core   +1 more source

Selective IgG4 deficiency and autoimmune cytopenias [PDF]

Exploration of Immunology
Aim: Autoimmune cytopenias are disorders driven by immune-mediated destruction of hematopoietic cells. Recent studies have linked these conditions to inborn errors of immunity (IEI), particularly in patients with recurrent and/or chronic forms.
Maria Loutsou, Nikolaos Giannakoulas, Emmanouel Ηatzipantelis, Helen Pergantou, Athina Dettoraki, Vasiliki Antari, Aikaterini Michalopoulou, George Vassilopoulos, Styliani Sarrou, Vasiliki Kalaitzidou, Christos Hadjichristodoulou, Fani Kalala, Matthaios Speletas   +12 more
doaj   +1 more source

Lymphoplasmacytic sclerosing pancreatitis without IgG4 tissue infiltration or serum IgG4 elevation: IgG4-related disease without IgG4 [PDF]

Modern Pathology, 2015
Type 1 autoimmune pancreatitis can be diagnosed by and is synonymous with its pathognomonic histopathologic appearance called lymphoplasmacytic sclerosing pancreatitis. Type 1 autoimmune pancreatitis, also called IgG4-related pancreatitis, is the pancreatic manifestation of IgG4-related disease.
Phil A, Hart, Thomas C, Smyrk, Suresh T, Chari   +2 more
openaire   +2 more sources