Results 31 to 40 of about 66,770 (302)

Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia. [PDF]

, 2017
BackgroundThe CXCR4-CXCL12 axis plays an important role in the chronic lymphocytic leukemia (CLL)-microenvironment interaction. Overexpression of CXCR4 has been reported in different hematological malignancies including CLL.
Amaya-Chanaga, Carlos I, Amine, Ale-Ali, Castro, Januario E, Choi, Michael Y, Fantin, Valeria R, Gu, Yin, Hallin, Max, Huser, Nanni, Kashyap, Manoj K, Kipps, Thomas J, Kumar, Deepak, Lindquist, Kevin, Liu, Shu-Hui, Pernasetti, Flavia, Rassenti, Laura Z, Simmons, Brett, Smeal, Tod, Yafawi, Rolla, Zhang, Cathy   +18 more
core   +4 more sources

Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma [PDF]

, 2019
Background: Sublingual allergen immunotherapy (SLIT) has been demonstrated to be both clinically efficacious and safe. However, in line with the current regulatory guidance from the European Medicines Agency, allergen immunotherapy (AIT) products must ...
Bachert, Claus, Boot, Johan D, de Kam, Pieter-Jan, Džupinová, Mária, Klimek, Ludger, Kuna, Piotr, Opstelten, Dirk Jan E, Panzner, Petr, Pfaar, Oliver, van Nimwegen, Maroesja J, Yu, Donghui   +10 more
core   +2 more sources

Does IgG4 level evaluation in pancreatic mass play role in avoiding major surgery in uncertain presentation: A case report

Indian Journal of Pathology and Microbiology, 2020
A 66-year-old male presented with chief complaints of anorexia associated with mild dull, intermittent epigastric pain for 6 months. The patient was a known diabetic on oral hypoglycemic and on routine checkup was found to have deranged liver function ...
Rakesh Kumar Gupta, Puja Sakhuja, Hari Govind, Anil Kumar Agarwal   +3 more
doaj   +1 more source

Anti-Neuronal IgG4 Autoimmune Diseases and IgG4-Related Diseases May Not Be Part of the Same Spectrum: A Comparative Study

Frontiers in Immunology, 2022
BackgroundIgG4 is associated with two emerging groups of rare diseases: 1) IgG4 autoimmune diseases (IgG4-AID) and 2) IgG4-related diseases (IgG4-RLD).
Verena Endmayr, Cansu Tunc, Lara Ergin, Anna De Rosa, Rosa Weng, Lukas Wagner, Thin-Yau Yu, Andreas Fichtenbaum, Thomas Perkmann, Helmuth Haslacher, Nicolas Kozakowski, Carmen Schwaiger, Gerda Ricken, Simon Hametner, Sigrid Klotz, Lívia Almeida Dutra, Christian Lechner, Christian Lechner, Désirée de Simoni, Désirée de Simoni, Kai-Nicolas Poppert, Georg Johannes Müller, Susanne Pirker, Walter Pirker, Aleksandra Angelovski, Matus Valach, Michelangelo Maestri, Melania Guida, Roberta Ricciardi, Florian Frommlet, Daniela Sieghart, Miklos Pinter, Karl Kircher, Gottfried Artacker, Romana Höftberger, Inga Koneczny   +35 more
doaj   +1 more source

Sequential CT Findings in Two Cases of Immunoglobulin G4-Related Lung Disease: Focused on Disease Progression

대한영상의학회지, 2018
Immunoglobulin G4 (IgG4)-related lung disease has been actively studied over the past few years. Radiologic findings of IgG4-related lung disease vary among patients, but there are no long-term follow up studies regarding variations in imaging features ...
Dong-Kyu Lee, Soo-Youn Ham
doaj   +1 more source

Clinical and morphological characteristics IgG4-associated retroperitoneal fibrosis

Alʹmanah Kliničeskoj Mediciny, 2020
Background: Retroperitoneal fibrosis (RF) is a rare disease with inflammation and fibrosis of the retroperitoneal soft tissues and adjacent organ involvement. At present, a proportion of RF cases are believed to be IgG4-associated.
S. V. Lishchuk, E. A. Dubova, K. A. Pavlov, A. M. Borbat, Yu. D. Udalov   +4 more
doaj   +1 more source

Autoimmune Pancreatitis - A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2015
Autoiommune pancreatitis (AIP) is a rare disease that has distinct histological, immunological, serological and radiological findings. It is characterised histologically by lymphoplasmacytic infiltrate, storiform fibrosis, obliterative phelibitis and ...
Varuna Mallya, KR Rathi, Kavita Sahai, CK Jakhmola   +3 more
doaj   +1 more source

Correlation between serologic parameters and disease activity of IgG4-related disease: Differences between patients with normal and elevated serum IgG4 concentrations

Frontiers in Immunology, 2022
ObjectiveWe aimed to identify serologic parameters that correlate with the disease activity of IgG4-related disease (IgG4-RD) in patients with normal and elevated serum IgG4 concentrations, respectively.MethodsThis retrospective cohort study included 148
Oh Chan Kwon, Min-Chan Park, Yong-Gil Kim, Yong-Gil Kim   +3 more
doaj   +1 more source

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells [PDF]

, 2012
Dendritic cells (DCs) can initiate and shape host immune responses toward either immunity or tolerance by their effects on antigen-specific CD4(+) T cells.
Akira, Anderson, Anna Karolina Palucka, Anne O’Garra, Anne-Laure Flamar, Awasthi, Bacchetta, Banchereau, Banchereau, Barrat, Baumgart, Bergman, Brown, Caparrós, Caux, Dapeng Li, Delneste, Dillon, Dorothée Duluc, Dudziak, Feng, Figdor, Gabrielle Romain, Gabrysová, Geijtenbeek, Geijtenbeek, Gerard Zurawski, Geurtsen, Gringhuis, Gringhuis, Groux, Häringer, Ito, Jacques Banchereau, Jankovic, Kaiser, Kappos, Klechevsky, LeibundGut-Landmann, Levings, Macián, Maldonado-López, Melissa Dullaers, Moore, Nathalie Bosquet, Ni, O’Garra, Pulendran, Reddy, Rissoan, Roger Le Grand, Rogers, Roncarolo, Sagoo, Saijo, Sandra Zurawski, SangKon Oh, Saraiva, Saraiva, Schreiber, Shortman, Smits, Soares, Steinman, Trinchieri, Valladeau, Xiao-Hua Li   +66 more
core   +2 more sources

Association of M-Type Phospholipase A2 Receptor Deposition in Kidney Tissue with Treatment Outcomes in Patients with Idiopathic Membranous Nephropathy

Journal of Inflammation Research, 2023
Ning-Qiu Xie,1,* Yu-Lin Zhang,2,* Zi-Li Zheng,1 Quan-Lin Zheng,1 Ruo-Ji Chen1 1Department of Nephrology, Jinjiang Municipal Hospital, Jinjiang, Fujian, 362200, People’s Republic of China; 2Department of Pediatric, Jinjiang Municipal Hospital ...
Xie NQ, Zhang YL, Zheng ZL, Zheng QL, Chen RJ   +4 more
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