Results 51 to 60 of about 66,770 (302)

A subset of ocular adnexal marginal zone lymphomas may arise in association with IgG4-related disease [PDF]

, 2015
We previously suggested a relationship between ocular immunoglobulin (Ig)G4-related disease (IgG4-RD) and marginal zone lymphomas (MZLs). However, the cytokine background associated with these disorders and whether it differs between ocular adnexal MZLs ...
Katsuyoshi, Takata, Koh-ichi, Ohshima, Kyotaro, Ohno, Mai, Takeuchi, Steven, H. Swerdlow, Tadashi, Yoshino, Tomoko, Miyata-Takata, Tomoyasu, Tachibana, Toshihiro, Ito, Yasuharu, Sato, Yorihisa, Orita, Yuka, Gion   +11 more
core   +1 more source

Disparities between IgG4-related kidney disease and extrarenal IgG4-related disease in a case–control study based on 450 patients

Scientific Reports, 2021
We aimed to compare the demographic, clinical and laboratory characteristics between IgG4-related kidney disease (IgG4-RKD+) and extrarenal IgG4-related disease (IgG4-RKD−) in a large Chinese cohort, as well as describing the radiological and ...
Qiaozhu Zeng, Jingyuan Gao, Xinyu Zhang, Aichun Liu, Zhenfan Wang, Ziqiao Wang, Xiying Chi, Qianyu Shi, Yi Wang, Fei Yang, Yanying Liu, Zhan-Guo Li   +11 more
doaj   +1 more source

A condition closely mimicking IgG4-related disease despite the absence of serum IgG4 elevation and IgG4-positive plasma cell infiltration [PDF]

, 2016
We describe a 74-year-old Japanese man with systemic fibroinflammatory conditions closely resembling those of immunoglobulin G4-related disease (IgG4-RD).
Fujita Kentaro, Hara Satoshi, Harada Kenichi, Kawano Mitsuhiro, Matsumura Masami, Mizushima Ichiro, Nagata Michio, Nakanuma Yasuni, Sato Yasuharu, Yamada Kazunori, Yamagishi Masakazu, Yamaguchi Yutaka, 長田 道夫   +12 more
core   +1 more source

Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti‐LGI1 Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Anti–leucine‐rich glioma‐inactivated 1 encephalitis (LGI1‐E) can cause persistent cognitive deficits, but the mechanisms remain unclear. A 40‐year‐old woman with LGI1‐E presented with subacute cognitive deficits and showed mild left medial temporal lobe (MTL) swelling and fluid‐attenuated inversion recovery (FLAIR) hyperintensity on initial ...
Yusuke Akitomi, Kenichiro Taira, Masanori Kurihara, Kenji Ishibashi, Kenji Ishii, Fumio Suzuki, Aya Midori Tokumaru, Makoto Hara, Atsushi Iwata   +8 more
wiley   +1 more source

IgG4-related nephropathy [PDF]

Journal of Nephrology, 2016
IgG4-related disease (IgG4-RD) is a recently recognized disorder, often with multiple organ involvement, characterized by dense tissue infiltration of IgG4-positive plasma cells, storiform fibrosis, obliterative phlebitis and frequently elevated serum IgG4 concentration. The kidney can be involved either directly or indirectly. The most frequent direct
Quattrocchio, Giacomo, ROCCATELLO, Dario
openaire   +3 more sources

Clinical and morphological characteristics of type 1 and 2 autoimmune pancreatitis

Alʹmanah Kliničeskoj Mediciny, 2018
Rationale: In the recent years, an increased interest to autoimmune pancreatitis (AIP) has been seen, related to growing diagnostic potential. In its turn, this leads to an increase in numbers of diagnosed AIP cases.
S. V. Lishchuk, Е. A. Dubova, K. А. Pavlov, Yu. D. Udalov   +3 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

The differential ability of human IgG1 and IgG4 to activate complement is determined by the COOH-terminal sequence of the CH2 domain. [PDF]

, 1991
Using domain switch chimeric antibodies, we confirm the important role of CH2 in complement activation. In addition, we demonstrate that the structures responsible for the differential ability of human IgG1 and IgG4 to activate complement are located at ...
Canfield, SM, Morrison, SL, Tao, MH
core  

Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease [PDF]

, 2017
IgG4-related disease (IgG4-RD) is characterized by elevated serum IgG4 and marked infiltration of IgG4-positive cells in multiple organs. Interleukin-33 (IL-33) is a recently described cytokine that is secreted by damaged epithelial cells, macrophages ...
Furukawa Sachiko, Hayashida Jun-Nosuke, Iizuka-Koga Mana, Ishiguro Noriko, Maehara Takashi, Miyake Kensuke, Moriyama Masafumi, Nakamura Seiji, Nakashima Hitoshi, Sumida Takayuki, Tanaka Akihiko, Tsuboi Hiroto, Yamauchi Masaki, 住田 孝之, 坪井 洋人   +14 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source