Results 51 to 60 of about 46,091 (305)

IgG4-related disease [PDF]

Acta Clinica Belgica, 2017
IgG4-related disease is a new term introduced in 2012 to assemble a number of formerly known diseases with common clinical, serological, and histopathological characteristics [1].
Bozzalla Cassione, Emanuele, Stone, John H.   +1 more
openaire   +5 more sources

IgG4-related sclerosing cholangitis mimicking hilar cholangiocarcinoma (Klatskin tumor): a case report of a challenging disease and review of the literature

Innovative Surgical Sciences, 2018
Even though IgG4-related disease has gained increased attention worldwide, the diagnosis remains challenging. IgG4-related sclerosing cholangitis (IgG4-SC) is not well described in the western hemisphere and may mimic cholangiocarcinoma (CC), especially ...
Mittelstaedt Anke, Meier Peter N., Dankoweit-Timpe Eva, Christ Beate, Jaehne Joachim   +4 more
doaj   +1 more source

THE SPECTRUM OF IGG4-RELATED DISEASES [PDF]

Romanian Journal of Medical Practice, 2018
IgG4-related disease (IgG4-RD) is now recognized as a worldwide disease. It is a rare systemic fibroinflammatory disorder. The evaluation for IgG4-RD should include a comprehensive clinical history, physical examination, and selected laboratory ...
Inimioara Mihaela Cojocaru, Manole Cojocaru   +1 more
doaj   +1 more source

IgG4-Related Disease Manifested as Cutaneous Plasmacytosis: A Case Report

, 2023
Weijia Wang,1– 3 Xiaojing Kang,1– 3 Yuan Ding,1– 3 Lidan Mao,1– 3 Abudureyimu Dilinuer,1– 3 Wenzheng Li1– 3 1Department of Dermatology and Venereology, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, People’s Republic of China; 2Xinjiang ...
Li W, Dilinuer A, Kang X, Ding Y, Wang W, Mao L   +5 more
core  

IgG4-Related Disease without Overexpression of IgG4: Pathogenesis Implications [PDF]

, 2012
IgG4-related disease is a new disease group that affects multiple organs. It is characterized by high serum IgG4 and abundant infiltration of IgG4-bearing plasma cells in the affected organ.
Masataka Kuwana, Hironari Hanaoka, Naoshi Nishina, Shuji Mikami, Tsutomu Takeuchi, Hideto Kameda, Yuko Kaneko   +6 more
core   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Diagnostic value of serum IgG and IgG4 in antineutrophil cytoplasmic antibody associated vasculitis

Di-san junyi daxue xuebao, 2019
Objective To investigate the expression of serum IgG and IgG4 in the patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), and explore the diagnostic value of IgG4 in AAV patients.
QIN Chenhao, GU Aiping, ZHAN Fuqin, FENG Ping, GU Haoyu   +4 more
doaj   +1 more source

IgG4-related kidney disease

, 2021
IgG4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory disease characterized by the formation of sclerotic tumor-like masses with dense lymphoplasmacytic infiltrates containing a significant number of IgG4-plasma cells.
D.I. Koliadenko, O.B. Iaremenko
core   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

IgG4-related disease and systemic vasculitis – is there any connection?

, 2014
IgG4-related disease is a relatively new group of diseases of still unknown etiology. It is characterized by elevated serum levels of subclass IgG4 immunoglobulin and by abundant infiltration of IgG4+ plasma cells with typical fibrosis of the affected ...
Anna Masiak, Zbigniew Zdrojewski
core   +1 more source