Results 61 to 70 of about 49,732 (222)

Long‐Term Outcomes of Low‐Dose Steroid Induction for Autoimmune Pancreatitis: A Multicenter Retrospective Study Identifying Risk Factors for Relapse

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Steroids are the first‐line treatment for autoimmune pancreatitis (AIP); however, the impact of lower initial doses on relapse remains unclear. Methods Ninety patients were divided into high‐dose (HD; > 0.4 mg/kg/day) and low‐dose (LD; ≤ 0.4 mg/kg/day) induction groups. The treatment response, relapse rate, and predictors of relapse
Yuhei Iwasa, Akinori Maruta, Keisuke Iwata, Hidetaka Kuroda, Shinya Uemura, Shota Iwata, Yosuke Ohashi, Naoki Mita, Hironao Ichikawa, Masahito Shimizu   +9 more
wiley   +1 more source

Clinical and immunological variants of ANCA-associated systemic vasculitis: a look at the phenomenon of IgG4 overproduction. Literature review and own observations

Научно-практическая ревматология, 2020
Systemic vasculitis (SV) associated with anti-neutrophilic cytoplasmic antibodies is a multifactorial process characterized by the variability of the epitope specificity of anti-neutrophilic cytoplasmic antibodies and the diversity of clinical phenotypes
T. V. Beketova, N. V. Kokosadze
doaj   +1 more source

IgG4-related disease and systemic vasculitis – is there any connection?

, 2014
IgG4-related disease is a relatively new group of diseases of still unknown etiology. It is characterized by elevated serum levels of subclass IgG4 immunoglobulin and by abundant infiltration of IgG4+ plasma cells with typical fibrosis of the affected ...
Anna Masiak, Zbigniew Zdrojewski
core   +1 more source

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

JEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz, Lars Matthies, Andrea Vanegas Ramirez   +2 more
wiley   +1 more source

The Solution Structures of Two Human IgG1 Antibodies Show Conformational Stability and Accommodate Their C1q and FcγR Ligands. [PDF]

, 2015
The human IgG1 antibody subclass shows distinct properties compared with the IgG2, IgG3, and IgG4 subclasses and is the most exploited subclass in therapeutic antibodies. It is the most abundant subclass, has a half-life as long as that of IgG2 and IgG4,
Jayesh Gor, Dalby, PA, Gor, J, Heenan, RK, Gar Kay Hui, Hui, GK, Lucy E. Rayner, Paul A. Dalby, Stephen J. Perkins, Rayner, LE, Richard K. Heenan, Perkins, SJ   +11 more
core   +1 more source

Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres, Jessi M. Larrinaga, Katherine Bodiford, Olayemi Sokumbi, Leila Tolaymat   +4 more
wiley   +1 more source

IgG4-related disease : why high IgG4 and fibrosis? [PDF]

, 2013
The hallmarks of IgG4-related disease (IgG4-RD) are lymphoplasmacytic tissue infiltration with a predominance of IgG4-positive plasma cells, accompanied by fibrosis, obliterative phlebitis, dacryoadenitis, and elevated levels of IgG4.
Koike, Takao
core   +1 more source

Angiosarcoma of the Scalp Presenting With Eyelid Edema: A Diagnostic Pitfall of Eyelid Biopsy

JEADV Clinical Practice, EarlyView.
ABSTRACT Angiosarcoma of the scalp is a rare but aggressive vascular malignancy that may present with nonspecific clinical findings, potentially leading to delayed diagnosis. Eyelid edema is an uncommon initial manifestation and has been suggested to result from direct tumor infiltration or lymphatic obstruction.
Sayo Komiyama, Sayaka Yamaguchi, Akiko Kaneshima, Aya Sunagawa, Shuhei Yonamine, Takuya Miyagi, Teruki Yanagi, Kenzo Takahashi   +7 more
wiley   +1 more source

Characterization Of The Homologs Of A Diagnostically Significant Brugia Malayi Gene (Bm17DIII) In Wuchereria Bancrofti, Loa Loa and Onchocerca Volvulus [RA644.F5 R788 2007 f rb]. [PDF]

, 2006
Satu ujian pantas yang dikenali sebagai BRUGIArapid (BR) yang mengesan antibodi IgG4 terhadap antigen rekombinan B. malayi (BmR1) adalah sangat berguna dalam pemetaan dan pengawasan kawasan yang endemik bagi filariasis brugia.
Abdul Aziz, Ros Azeana
core   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source