Results 61 to 70 of about 66,770 (302)
Hypereosinophilic syndrome with elevated IgG4 and T-cell clonality: A report of two cases
Open Life SciencesIn some cases, higher IgG4 levels are accompanied by increased circulating IgE, higher eosinophil counts, and various autoantibodies. Among these cases, IgG4-related disease (IgG4-RD) is one of the most frequently diagnosed conditions.
Huang Meichun +3 more
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Innovative Surgical Sciences, 2018 Even though IgG4-related disease has gained increased attention worldwide, the diagnosis remains challenging. IgG4-related sclerosing cholangitis (IgG4-SC) is not well described in the western hemisphere and may mimic cholangiocarcinoma (CC), especially ...
Mittelstaedt Anke +4 more
doaj +1 more source
Advanced Science, EarlyView.CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu +13 more
wiley +1 more source
Diagnostic value of serum IgG and IgG4 in antineutrophil cytoplasmic antibody associated vasculitis
Di-san junyi daxue xuebao, 2019 Objective To investigate the expression of serum IgG and IgG4 in the patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), and explore the diagnostic value of IgG4 in AAV patients.
QIN Chenhao +4 more
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Tolosa–Hunt Syndrome and IgG4 diseases in Neuro-Ophthalmology
Annals of Indian Academy of Neurology, 2022 Tolosa–Hunt syndrome (THS) remains a challenging diagnosis for many neurologists. Often believed to be a rare presentation, the classical presentation is known to involve cranial nerves and tissues surrounding the cavernous sinus.
Aastha Takkar Kapila +2 more
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Serum BAFF and APRIL levels in patients with IgG4-related disease and their clinical significance. [PDF]
, 2012 [Introduction]B cell-activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL) play a crucial role in B cell development, survival, and antibody production.
Fujii, Takao +8 more
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T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Rosai–Dorfman disease mimicking IgG4-related diseases: a single-center experience in China
Orphanet Journal of Rare Diseases, 2020 Background Rosai–Dorfman disease (RDD) and IgG4-related (IgG4-RD) disease are both rare diseases, but in some cases, RDD mimics IgG4-RD clinically and pathologically. RDD mimicking IgG4-RDs (RDD mimic IgG4-RD), referring to disease initially diagnosed as
Li Wang +9 more
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THE SPECTRUM OF IGG4-RELATED DISEASES [PDF]
Romanian Journal of Medical Practice, 2018 IgG4-related disease (IgG4-RD) is now recognized as a worldwide disease. It is a rare systemic fibroinflammatory disorder. The evaluation for IgG4-RD should include a comprehensive clinical history, physical examination, and selected laboratory ...
Inimioara Mihaela Cojocaru +1 more
doaj +1 more source
Okayama Igakkai Zasshi (Journal of Okayama Medical Association), 2010 IgG4-related disease is a recently recognized systemic syndrome characterized by mass-forming lesions, mainly in exocrine tissue, that consist of lymphoplasmacytic infiltrates and sclerosis. There are numerous IgG4+ plasma cells in the affected tissues, and the serum IgG4 level is elevated in these patients.
Yasuharu, Sato, Tadashi, Yoshino
openaire +3 more sources