Results 231 to 240 of about 46,091 (305)

Induction and Prolonged Induction With Mirikizumab in Ulcerative Colitis—A Prospective, Real‐World Study From the Sicilian Network for Inflammatory Bowel Disease (SN‐IBD)

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background Mirikizumab (MIRI), an IgG4 monoclonal antibody targeting IL‐23 p19, was recently licensed for ulcerative colitis (UC). Most available data come from the pivotal trials, but real‐life data are scant. We aimed to evaluate the effectiveness and safety of MIRI in a real‐world setting.
Giuseppe Costantino, Anna Viola, Andrea Iuculano, Fabio Salvatore Macaluso, Raffaele Li Voti, Maria Cappello, Chiara Antoci, Concetta Ferracane, Morena Sciuto, Domenico Catarella, Stefanie Parisi, Filippo Mocciaro, Barbara Scrivo, Maria Emanuela Distefano, Roberto Vassallo, Maria Giovanna Minissale, Giuseppe Scalisi, Serena Garufi, Sofia Rao, Stefano Muscarella, Vincenza Tortorella, Emiliano Giangreco, Marco Muscianisi, Ambrogio Orlando, Walter Fries   +24 more
wiley   +1 more source

A Tangled Tale: Type 2 Autoimmune Pancreatitis With a Sclerosing Twist. [PDF]

ACG Case Rep J
Husain KH, Hagen R, Thakkar B, Promagan N, Parikh ND.   +4 more
europepmc   +1 more source

Medical Literature in the Age of Artificial Intelligence

iNew Medicine, Volume 2, Issue 2, June 2026.
Hunter Scott
wiley   +1 more source

The evolving role of structural biology in pharma: integration of X‐ray crystallography, cryo‐electron microscopy and beyond

Acta Crystallographica Section D, Volume 82, Issue 6, Page 587-602, June 2026.
This review describes how an integrated structural biology platform at Merck Sharp & Dohme LLC, Rahway, New Jersey, USA, combining X‐ray crystallography, cryo‐EM, MicroED and cryo‐ET, enables seamless three‐dimensional insights from molecular to cellular length scales.
Jill E. Chrencik, Hua-Poo Su, Yacob Gomez Llorente, Rachel L. Palte, Daniel J. Klein, Robert P. Hayes, Sadie P. Antine, Guilermo A. Asmar-Rovira, Nicole Bertoletti, Noel J. Byrne, Brittany L. Carroll, Ciro D. Cordeiro, Kaylynn Curfman, James Dutko, Michael J. Eddins, Thierry Fischmann, Barani Govindarajan, Corey W. Hecksel, Thu Ho, Kaspar Hollenstein, Mee Ra Hong, Alan Hruza, Andrii Ishchenko, Maru Jaime-Garza, Matt J. Jaremko, Hayley L. Knox, James Kostas, Harini Krishnamurthy, Ioannis Manolaridis, Cameron L. Noland, Andrea T. Partridge, Sangita B. Patel, Paul Reichert, John C. Reid, Catarina Felisberto-Rodrigues, Chitra A. Shintre, Jennifer M. Shipman, Elakkiya Tamilselvan, Morgan E. Walker, Susanne N. Walker, Renjing Wang, Katharine M. Wright, Tien-Jui Yen, Byung-Kuk Yoo, Sandra B. Gabelli   +44 more
wiley   +1 more source

Multimodality imaging for diagnosing and monitoring immunoglobulin G4-related coronary arteritis presenting as giant aneurysm: a case description. [PDF]

Quant Imaging Med Surg
Jiang H, Wang J, Ping L.
europepmc   +1 more source

Peanut Component‐Specific IgE and IgG4 Are Modulated by Sublingual Immunotherapy and Are Associated With Remission in 1–4‐Year‐Old Children

Allergy, Volume 81, Issue 6, Page 2089-2102, June 2026.
This study presents a post hoc analysis of longitudinal changes in peanut component‐specific IgE and IgG4 in children aged 1–4 years undergoing peanut SLIT, aiming to uncover immune mechanisms and potential biomarkers of remission. Peanut SLIT reduced IgE and increased IgG4 responses to Ara h 1, Ara h 2, Ara h 3, and Ara h 6.
Neel Singh, Janelle Kesselring, Jess Humphrey, Lauren Herlihy, A. Wesley Burks, Johanna Smeekens, Corinne Keet, J. Andrew Bird, Edwin H. Kim, Michael Kulis   +9 more
wiley   +1 more source

Case Report: A steroid-sparing mechanical management of IgG4-related sclerosing cholangitis mimicking cholangiocarcinoma. [PDF]

Front Immunol
Liu Z, Wang A, Cao Y, Zhao X.
europepmc   +1 more source

Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses

Allergy, Volume 81, Issue 6, Page 2111-2122, June 2026.
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong, Kati Palosuo, Victoria Hinkkanen, Vittorio Fortino, Mika J. Mäkelä, Piia Karisola   +5 more
wiley   +1 more source

IgG4-Related Retroperitoneal Fibrosis Presenting as Obstructive Acute Kidney Injury: A Case Report. [PDF]

Cureus
Jarai MZ, Haider SY, Eldesouki S, Hashemi S, Nejad S, Elbadawi F, Mahjoor Azad E, Bagheri F.   +7 more
europepmc   +1 more source