Results 231 to 240 of about 66,770 (302)

Optimizing Body Size‐Based Dosing Approaches for Antibody–Drug Conjugates

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 872-880, April 2026.
Optimized dosing precision of antibody–drug conjugates (ADCs) remains challenging due to narrow therapeutic indices, efficacious doses near the maximum tolerated dose, and substantial interindividual variability in exposure. Body size‐based dosing can reduce exposure variability when the allometric scaling exponent for clearance α = 1 but may over‐ or ...
Andrew B. SyBing, Diane D. Wang
wiley   +1 more source

SARS-CoV-2 Anti-Spike IgG Subclass Titres in a Population with Prior Exposure to Perfluorooctanoic Acid (PFOA). [PDF]

Toxics
Zamfir M, Gerstner D, Lahne H, Fingerle V, Redwitz J, Schober W, Aschenbrenner B, Graw M, Nowak D, Quartucci C, Herr C, Heinze S.   +11 more
europepmc   +1 more source

IgG4-related sclerosing cholangitis: navigating diagnostic dilemmas and the challenge of relapse. [PDF]

Front Med (Lausanne)
Ren X, Jin X, Liu L, Zhang M.
europepmc   +1 more source

Successful Endoscopic Excision for a Rapidly Enlarging Esophageal Histopathologically Unclassified Subepithelial Lesion: A Case Report

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 75‐year‐old man presented with an esophageal subepithelial lesion (SEL) measuring 2.5 cm, first identified over a decade ago. The patient was followed up regularly with computed tomography and endoscopy and remained asymptomatic since then. However, over the past year, the patient developed dysphagia, and endoscopic evaluation revealed that ...
Mai Fukuda, Naoya Tada, Miku Maeda, Koichi Oishi, Mamoru Ito, Yuko Hasegawa, Toshiki Futakuchi, Masakuni Kobayashi, Naoto Tamai, Masayuki Shimoda, Kazuki Sumiyama   +10 more
wiley   +1 more source

Distal Bile Duct Metastasis From Rectal Cancer: The Diagnostic Contribution of Intraductal Ultrasonography

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 49‐year‐old male developed liver dysfunction during chemotherapy for rectal cancer located in the rectosigmoid region. Although magnetic resonance cholangiopancreatography initially indicated sclerosing cholangitis, endoscopic retrograde cholangiopancreatography and intraductal ultrasonography revealed multiple non‐contiguous intraductal ...
Shinji Monoe, Ryo Nishio, Arihiro Nakano, Yu Yasue, Takahiro Yamashita, Hitoshi Iwata   +5 more
wiley   +1 more source

Correction: Vernia et al. Immunoglobulin G4-Related Disease of the Intestine: A Clinicopathological Entity to Be Considered. <i>Medicina</i> 2024, <i>60</i>, 57. [PDF]

Medicina (Kaunas)
Vernia F, Cirella L, Calvisi G, Viscido A, Latella G.   +4 more
europepmc   +1 more source

Endoscopic Ultrasound‐guided Fine‐Needle Biopsy With End‐Cutting Needles in Autoimmune Pancreatitis: A Systematic Review and Meta‐Analysis

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives There is limited evidence on the diagnostic yield of endoscopic ultrasound (EUS)‐guided tissue acquisition (TA) using fine‐needle biopsy (FNB) in autoimmune pancreatitis (AIP), particularly considering the newer end‐cutting needles.
Antonio Facciorusso, Maria Cristina Conti Bellocchi, Nicolò De Pretis, Luca Frulloni, Stefano Francesco Crinò   +4 more
wiley   +1 more source

Intralesional Corticosteroid Therapy for Isolated Immunoglobulin G4-Related Esophageal Involvement: A Novel Approach to a Rare Condition. [PDF]

ACG Case Rep J
Alhanaktah B, Chishti E, Shelman NR, Ismail B.   +3 more
europepmc   +1 more source

Broad immunogenicity of house dust mite proteins contrasts restricted specific IgE and IgG4 associated with allergy. [PDF]

PLoS One
Christensen LH, Petersen JEV, Lund G, Holm J, Würtzen PA, Wiborg J, Ipsen H, Johansen N, Stranzl T, Andersen PS.   +9 more
europepmc   +1 more source

Multicenter Validation Study of the Clinical Diagnostic Criteria for IgG4‐Related Sclerosing Cholangitis 2020 in Japan

Journal of Hepato-Biliary-Pancreatic Sciences, Volume 33, Issue 4, Page 294-303, April 2026.
In this Japanese multicenter validation study, Naitoh and colleagues analyzed clinical data from 1034 patients with IgG4‐related sclerosing cholangitis to evaluate the 2020 clinical diagnostic criteria. The IgG4‐SC2020 criteria demonstrated higher sensitivity than the 2012 criteria while maintaining high specificity, and reclassified cases not ...
Itaru Naitoh, Takahiro Nakazawa, Kensuke Kubota, Takayoshi Nishino, Akira Nakamura, Dai Inoue, Takanori Sano, Kazuhiro Kikuta, Yusuke Kurita, Kazuro Chiba, Tsukasa Ikeura, Hiroyuki Matsubayashi, Takuya Ishikawa, Masaki Kuwatani, Terumi Kamisawa, Ichiro Yasuda, Mitsuhiro Kawano, Atsushi Masamune, Japan Pancreatitis Study Group, Yoko Abe, Atsushi Irisawa, Hiroyuki Tanaka, Eizaburo Ohno, Tatsuru Maruo, Toshiharu Ueki, Rei Suzuki, Tadayuki Takagi, Hiromasa Ohira, Shirou Tanoue, Akio Ido, Takahiro Komori, Kayashima Atsuo, Masayasu Horibe, Eisuke Iwasaki, Masahiro Tsujimae, Yuzo Kodama, Kazushige Uchida, Masayuki Ueno, Kenji Notohara, Shotaro Kakehashi, Nao Fujimori, Eiji Nakatani, Yasuki Hori, Michihiro Yoshida, Hiroki Kawashima, Kazunao Hayashi, Shuji Terai, Kosaku Morimoto, Ryosuke Sato, Kazuyuki Matsumoto, Hironari Kato, Yoshiharu Masaki, Hiroshi Nakase, Toshihiko Arizumi, Atsushi Tanaka, Ryotaro Matusmoto, Tetsuya Takikawa, Ryosuke Tonozuka, Takao Itoi, Kenji Hirano, Nobuhiko Hayashi   +60 more
wiley   +1 more source