Results 241 to 250 of about 66,770 (302)

Esophageal tissue immunoglobulin G4 in eosinophilic esophagitis and its correlation with serum-specific IgG4 to six foods. [PDF]

Front Allergy
Macías E, Menéndez-Ramos A, Velasco-Guardado A, Muñoz-León JA, Rodríguez-González M, Dávila I.   +5 more
europepmc   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

IgG4 Neutralization and Sustained Total IgG Fc-Effector Functions Following Repeated SARS-CoV-2 Vaccination with mRNA-1273. [PDF]

Infect Dis Ther
Kaplonek P, Bertera H, Lee DW, Cizmeci D, Yu WH, Wu K, Chalkias S, Wahid R, Edwards D, Alter G, Henry C.   +10 more
europepmc   +1 more source

Results and Exploratory Biomarker Analyses of a Phase II Study CHANGEABLE: Combination of PD‐1 Inhibitor and Niraparib in GErm‐Line‐mutAted Metastatic Breast Cancer

MedComm, Volume 7, Issue 4, April 2026.
This phase II trial evaluated the efficacy and safety of niraparib combined with HX008 in metastatic breast cancer (MBC) patients with germline DNA damage response (DDR) gene mutations. This chemotherapy‐free regimen demonstrates promising efficacy and a tolerable safety profile in MBC patients with germline DDR mutations, providing a novel therapeutic
Jian Zhang, Yiqun Du, Yanchun Meng, Yizi Jin, Mingxi Lin, Xuchen Shao, Xiaojun Liu, Yuxin Mu, Yun Liu, Zhen Hu   +9 more
wiley   +1 more source

Application of artificial intelligence in differentiating IgG4-related ophthalmic disease and orbital MALT lymphoma: a review of radiomics and deep learning advances. [PDF]

Front Immunol
Weng W, Chen Y, Jin R, Chen J, Gao Y, Li Y, Shao H, Bao S, Xue W.   +8 more
europepmc   +1 more source

Immunocompromised Status Definition in Observational Studies Using Electronic Health Records: A Scoping Review and a Proposal for a Phenotype Identification Algorithm

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 4, April 2026.
ABSTRACT Immunocompromised individuals experience an impaired immune function due to conditions that might be either congenital or acquired over the course of their lives. Epidemiological studies often rely on clinical definitions which, in some cases, benefit from being translated into machine‐readable algorithms for application to electronic health ...
Judit Riera‐Arnau, Nicoletta Luxi, Fabio Riefolo, Martín Solorzano, Irene Pazos, Elena Ballarín, Lise Skovgaard Svingel, Lorenzo Chiusaroli, Elisa Martín‐Merino, Elisa Barbieri, María Lopez‐Lasanta, Sima Mohammadi, Denis Rotta, Alexandra Pacurariu, Catherine Cohet, Miriam Sturkenboom, Carlos E. Durán, on behalf of the SAFETY‐VAC study consortium, Carlos E. Durán, Miriam Sturkenboom, Judit Riera‐Arnau, Nicoletta Luxi, Olaf Klungel, Patrick Souverein, Sima Mohammadi, Fabio Riefolo, Irene Pazos, Rosa Gini, Davide Messina, Giuseppe Roberto, Carlo Giaquinto, Elisa Barbieri, Luca Stona, Felipe Villalobos, Martín Solorzano, Carlo Alberto Bissacco, Antonio Gimeno, Beatriz Poblador, Mercedes Aza, Aida Moreno, Alejandro Santos, Vera Ehrenstein, Lise Skovgaard Svingel, Benjamin Randeris Johannesen, Cécile Droz‐Perroteau, Laure Carcaillon‐Bentata, Anna‐Mija Tolppanen, Sirpa Hartikainen, Thuan Vo, Anne Paakinaho, Blair Rajamaki, Hedvig Nordeng, Saeed Hayati, Mahmoud Zidan, Juan José Carreras Martínez, Arantxa Urchueguía Fornes, Elisa Correcher Martínez, Javier Díez‐Domingo, Mar Martin, Patricia Garcia‐Poza, Airam de Burgos, Belén Castillo‐Cano, Elisa Martín‐Merino   +62 more
wiley   +1 more source

Azathioprine as maintenance therapy for IgG4-related diseases: a retrospective case series and case-based review of the literature. [PDF]

Rheumatol Int
Reisch M, Spindelböck WJ, Hodl I, Pietsch D, Rainer F, Kickinger D, Sutic A, Thiel J, Stradner M.   +8 more
europepmc   +1 more source

Population Pharmacokinetics of Serplulimab and Quantitative Assessment of Transitioning From Weight‐Based to Flat‐Dosing Strategy

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 4, April 2026.
ABSTRACT Serplulimab is a fully humanized anti–PD‐1 monoclonal antibody approved for small‐cell lung cancer and other malignancies. The initial dosing strategy was based on body weight (WT‐based); however, flat‐dosing offers greater convenience and reduced variability.
Kun Wang, Yuanyuan Shen, Chen Hu, Fengyan Xu, Zhihao Kwok, Qingyu Wang, Yaqi Lin, Yuying Gao, Liang Zhou   +8 more
wiley   +1 more source

A Case of IgG4-Related Disease That Mimics an Anterior Mediastinal Malignant Tumour. [PDF]

Respirol Case Rep
Nishimura N, Nakamura Y, Yazawa N, Goto Y, Suzuki T, Inoue T, Hasegawa A, Ikeda K, Takemasa A, Chida M, Ishida K, Shimizu Y, Niho S.   +12 more
europepmc   +1 more source

Synergistic Antitumor Efficacy of Radiofrequency Ablation Combined With TROP2‐CAR‐T Cells in a Xenograft Mouse Model of Lung Adenocarcinoma

Thoracic Cancer, Volume 17, Issue 7, April 2026.
Combining radiofrequency ablation with TROP2‐CAR‐T cells results in synergistic tumor suppression and minimal systemic toxicity in vivo, supporting local ablation as a strategy to enhance CAR‐T therapy for solid tumors. ABSTRACT Background Lung adenocarcinoma (LUAD) is highly relapsed and responds poorly to chimeric antigen receptor (CAR)‐T therapy due
Yanyun Zhao, Peng Jiao, Zhuo Zhang, Yang Sun, Huiyan Sun, Xiaoguang Li, Zhixin Bie, Chenghua Xiao, Yanfei Qu, Wei Wang, Qinqin Xu, Lisheng Wang   +11 more
wiley   +1 more source