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Serum IgG4 Concentration in IgG4-Related Disease
Clinical Laboratory, 2017IgG4-related disease (IgG4-RD) is an immune-mediated and chronic fibroinflammatory condition that affects almost any organ and often involves multiple organs in the same patient. In this review article, we address the clinical utility of measuring serum immunoglobulin G subclass 4 concentration ([IgG4]) in IgG4-RD diagnosis and in disease monitoring.We
Shigeyuki, Kawa +4 more
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Diagnostic performances of serum IgG4 concentration and IgG4/IgG ratio in IgG4-related disease
Clinical Rheumatology, 2017Patients with IgG4-related disease (IgG4-RD) often have elevated serum IgG4 levels. Here, we aimed to evaluate the diagnostic performances of elevated serum IgG4 concentration and IgG4/IgG ratio for IgG4-RD. We retrospectively analyzed 1381 patients subjected to serum IgG subclass testing to differentiate IgG4-RD from other diseases at Peking ...
Chang-sheng Xia +2 more
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Seminars in Liver Disease, 2016
Immunoglobulin G4-related disease (IgG4-RD) is a systemic disease involving many organs; it includes IgG4-related sclerosing cholangitis and inflammatory pseudotumor in the hepatobiliary system. Two types of hepatic parenchymal involvement have been reported in IgG4-RD: IgG4-related autoimmune hepatitis (AIH) and IgG4-hepatopathy.
Yasuni, Nakanuma +4 more
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Immunoglobulin G4-related disease (IgG4-RD) is a systemic disease involving many organs; it includes IgG4-related sclerosing cholangitis and inflammatory pseudotumor in the hepatobiliary system. Two types of hepatic parenchymal involvement have been reported in IgG4-RD: IgG4-related autoimmune hepatitis (AIH) and IgG4-hepatopathy.
Yasuni, Nakanuma +4 more
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Serum IgG4 concentrations and IgG4-related sclerosing disease
Clinica Chimica Acta, 2009Based on histological and immunohistochemical examinations of various organs of patients with autoimmune pancreatitis (AIP), a new clinicopathological entity, IgG4-related systemic disease, was proposed. This study aimed to clarify clinical utility of serum IgG4 levels in differentiating AIP from other pancreatobiliary diseases, clinical utility of ...
Taku, Tabata +10 more
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Current Opinion in Rheumatology, 2011
An enlarged salivary gland or lacrimal gland raises a wide differential diagnosis that includes both benign inflammatory conditions and malignant disorders. This review aims to address the numerous controversies that have arisen regarding inflammatory diseases of the salivary gland over the past two centuries and more specifically address the relevance
Julia T, Geyer, Vikram, Deshpande
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An enlarged salivary gland or lacrimal gland raises a wide differential diagnosis that includes both benign inflammatory conditions and malignant disorders. This review aims to address the numerous controversies that have arisen regarding inflammatory diseases of the salivary gland over the past two centuries and more specifically address the relevance
Julia T, Geyer, Vikram, Deshpande
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Current Rheumatology Reports, 2013
Elevated IgG4 is characteristic of cases of IgG4-RD, a newly recognized systemic disease. However, several chronic inflammatory conditions, including rheumatic diseases, can also be associated with increased levels of IgG4. There have also recently been several reports describing an increased IgG4 immune response to some vasculitis syndromes, in ...
Rodolfo, Perez Alamino +2 more
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Elevated IgG4 is characteristic of cases of IgG4-RD, a newly recognized systemic disease. However, several chronic inflammatory conditions, including rheumatic diseases, can also be associated with increased levels of IgG4. There have also recently been several reports describing an increased IgG4 immune response to some vasculitis syndromes, in ...
Rodolfo, Perez Alamino +2 more
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A Review of IgG4-related Sclerosing Cholangitis (IgG4-SC)
Journal of Clinical GastroenterologyIgG4-related sclerosing cholangitis (IgG4-SC) is a unique, steroid-responsive, fibroinflammatory condition that is more commonly found in older men and is strongly associated with autoimmune pancreatitis (AIP). It may pose a diagnostic challenge at times due to closely mimicking hepatobiliary diseases such as primary sclerosing cholangitis (PSC ...
Neil C, Khoury, John W, Birk
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Seminars in Diagnostic Pathology
IgG4-related lymphadenopathy is a nodal manifestation of IgG4-related disease (IgG4RD) which is characterized by increased polytypic IgG4+ plasma cells and IgG4+/IgG+ plasma cell ratio in lymph nodes and morphologically manifested as various patterns of reactive lymphadenopathy: Castleman disease-like, follicular hyperplasia, interfollicular expansion,
Wah Cheuk, Jacob R. Bledsoe
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IgG4-related lymphadenopathy is a nodal manifestation of IgG4-related disease (IgG4RD) which is characterized by increased polytypic IgG4+ plasma cells and IgG4+/IgG+ plasma cell ratio in lymph nodes and morphologically manifested as various patterns of reactive lymphadenopathy: Castleman disease-like, follicular hyperplasia, interfollicular expansion,
Wah Cheuk, Jacob R. Bledsoe
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2016
IgG4-related disease (IgG4-RD) is a fibro-inflammatory condition characterized by fibrous swelling of affected organs, elevated serum IgG4 concentration in the majority of patients, and a prompt response to corticosteroid therapy. The concept of IgG4-RD as a novel clinical entity emerged at the beginning of the twenty-first century, when Hamano and ...
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IgG4-related disease (IgG4-RD) is a fibro-inflammatory condition characterized by fibrous swelling of affected organs, elevated serum IgG4 concentration in the majority of patients, and a prompt response to corticosteroid therapy. The concept of IgG4-RD as a novel clinical entity emerged at the beginning of the twenty-first century, when Hamano and ...
openaire +3 more sources