Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery
Advanced Healthcare Materials, EarlyView.Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang +6 more
wiley +1 more source
Deficiency in Serum Immunoglobulin (Ig)m Predisposes to Development of Igg Autoantibodies [PDF]
, 2000 Michael R. Ehrenstein +2 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu +9 more
wiley +1 more source
A Case of Chronic Intractable Diarrhea with IgA, IgG2 and IgG4 Deficiency [PDF]
, 2001 Sung Ryon Ahn +4 more
openalex +1 more source
ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing
Advanced Healthcare Materials, EarlyView.A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha +4 more
wiley +1 more source
HLA-A and -B alleles and haplotypes in 240 index patients with common variable immunodeficiency and selective IgG subclass deficiency in central Alabama [PDF]
, 2003 James C. Barton +2 more
openalex +1 more source
Recurrent skin and soft tissue infections as a presentation of Primary Selective Immunoglobuline M Deficiency [PDF]
, 2015 Bogaert, Anne-Marie +2 more
core +2 more sources
Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
Advanced Healthcare Materials, EarlyView.A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li +8 more
wiley +1 more source
A novel immunoglobulin phenotype: Profound deficiency of IgM, IgD, IgA, and IgE with normal IgG [PDF]
, 2005 Jyotsna Patel, David P. Huston
openalex +1 more source
Advanced Healthcare Materials, EarlyView.A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben +8 more
wiley +1 more source