Results 271 to 280 of about 259,280 (346)

Improvement of the predictive value of CD4+ lymphocyte count by b2-microglobulin, immunoglobulin A and erythrocyte sedimentation rate [PDF]

, 1993
Bek, Barbara, Bogner, Johannes R., Burkowitz, Jörg, Koch, Judith, Koch, Meinrad A., Schwartländer, Bernhard, Skarabis, Horst   +6 more
core  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Ultra-short celiac disease in children: histological and autoimmune features. [PDF]

Eur J Pediatr
Demir AM, Hızal G, Ateş BB, Akbaba B, Kırsaçlıoğlu CT, Hızlı Ş, Karakuş E.   +6 more
europepmc   +1 more source

IgG subclass deficiency in children

Journal of Microbiology and Genetics, 2019
openaire   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

A Case of Cryptococcal Meningitis in an Immunocompetent Individual. [PDF]

Cureus
Baumgartner E, Weltin L, Farrell JJ.
europepmc   +1 more source

IgG Lambda Myeloma Presented With Haemophagocytic Lymphohistiocytosis (HLH) Successfully Treated With VTD Induction and Melphalan Autograft. [PDF]

EJHaem
Xu K, Childerhouse A, Kyriakou C.
europepmc   +1 more source

Immune Checkpoint Inhibitor-Associated Autoimmune Diabetes Mellitus: An Indian Case Series. [PDF]

Cureus
Rao MN, Chopra A, Hegde AG, S AK, Sriharsha G.   +4 more
europepmc   +1 more source