Results 21 to 30 of about 259,280 (346)

Iron Deficiency Anemia at Time of Vaccination Predicts Decreased Vaccine Response and Iron Supplementation at Time of Vaccination Increases Humoral Vaccine Response: A Birth Cohort Study and a Randomized Trial Follow-Up Study in Kenyan Infants

Frontiers in Immunology, 2020
Background: Iron deficiency may impair adaptive immunity and is common among African infants at time of vaccination. Whether iron deficiency impairs vaccine response and whether iron supplementation improves humoral vaccine response is uncertain.Methods:
Nicole U. Stoffel, Mary A. Uyoga, Francis M. Mutuku, Joe N. Frost, Edith Mwasi, Daniela Paganini, Fiona R. M. van der Klis, Indu J. Malhotra, A. Desiráe LaBeaud, Cristian Ricci, Simon Karanja, Hal Drakesmith, Hal Drakesmith, Charles H. King, Michael B. Zimmermann   +14 more
doaj   +1 more source

Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD

Respiratory Research, 2018
Background The literature is scarce regarding the prevalence and clinical impact of IgG subclass deficiency in COPD. We investigated the prevalence of IgG subclass deficiencies and their association with exacerbations and hospitalizations using subjects ...
Fernando Sergio Leitao Filho, Seung Won Ra, Andre Mattman, Robert S. Schellenberg, Gerard J. Criner, Prescott G. Woodruff, Stephen C. Lazarus, Richard Albert, John E. Connett, Meilan K. Han, Fernando J. Martinez, Janice M. Leung, S. F. Paul Man, Shawn D. Aaron, Robert M. Reed, Don D. Sin, for the Canadian Respiratory Research Network (CRRN)   +16 more
doaj   +1 more source

Serum Protein Electrophoresis May Be Used as a Screening Tool for Antibody Deficiency in Children and Adolescents

Frontiers in Immunology, 2021
BackgroundPatients with antibody deficiency may experience exceptionally long diagnostic delays, increasing the risk of life-threatening infections, end-organ damage, mortality, and health costs.ObjectiveThis study aimed to analyze serum protein ...
Cristina Frias Sartorelli de Toledo Piza, Carolina Sanchez Aranda, Dirceu Solé, Stephen Jolles, Antonio Condino-Neto   +4 more
doaj   +1 more source

Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]

, 2017
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo, Liumbruno, Giancarlo Maria, Marano, Giuseppe, Mengoli, Carlo, Piccinini, Vanessa, Pupella, Simonetta, Vaglio, Stefania   +6 more
core   +1 more source

Daily preventive zinc supplementation increases the antibody response against pathogenic Escherichia coli in children with zinc insufficiency: a randomised controlled trial

Scientific Reports, 2022
Zinc deficiency impairs the antibody-mediated immune response and is common in children from lower-income countries. This study aimed to investigate the impact of different zinc supplementation regimens (7, 10 or 20 mg/day elemental zinc)—therapeutic ...
Chidchamai Kewcharoenwong, Myint Myint Sein, Arnone Nithichanon, Aranya Khongmee, K Ryan Wessells, Guy-Marino Hinnouho, Maxwell A. Barffour, Sengchanh Kounnavong, Sonja Y. Hess, Charles B. Stephensen, Ganjana Lertmemongkolchai   +10 more
doaj   +1 more source

Fn14 Deficiency Ameliorates Anti-dsDNA IgG-Induced Glomerular Damage in SCID Mice

Journal of Immunology Research, 2018
Many studies have demonstrated that anti-dsDNA IgG is closely associated with lupus nephritis. Recently, it was found that activation of the fibroblast growth factor-inducible 14 (Fn14) signaling pathway damages glomerular filtration barrier in MRL/lpr ...
Jiawen Wu, Xiaoyun Min, Li Wang, Jie Yang, Ping Wang, Xingyin Liu, Yumin Xia   +6 more
doaj   +1 more source

ATOPIC DERMATITIS – ASSOCIATED IMMUNE DYSFUNCTION [PDF]

Romanian Journal of Pediatrics, 2016
The immune system shows a complex role to defend the body in response to “non-self” antigens, respond abnormally to antigens allergens (hypersensitivity and autoimmunity) and shows immune tolerance by lack of reactivity to its own structures (self). Aim.
Sempronia Ecaterina Coclici, Dana Elena Mindru, Vasile Valeriu Lupu, Evelina Moraru, Laura Iulia Bozomitu   +4 more
doaj   +1 more source

Subcutaneous IgG Replacement Therapy by Push in 32 Patients with Primary Immunodeficiency Diseases in Argentine [PDF]

, 2014
Introduction: Regular replacement with immunoglobulin infusions is the mainstay of treatment in the majority of primary immunodeficiencies. Several studies showed that Subcutaneous Immunoglobulin (SCIG) has similar efficacy to Intravenous Immunoglobulin (
Bezrodnik, Liliana, Díaz Ballve, Damacia, Giovanni, Daniela Di, Gómez Raccio, Andrea, Moreira, Ileana, Regairaz, Lorena, Seminario, Gisela   +6 more
core   +1 more source

Effects of Methionine Deficiency on the B Lymphocyte and Immunoglobulins of Cecal Tonsil in Cobb Broilers [PDF]

Brazilian Journal of Poultry Science, 2019
The present study was conducted on one-day-old broilers to investigate the effects of methionine deficiency on B lymphocytes and immunoglobulins (sIgA, IgA, IgG, IgM) in the cecal tonsil of Cobb broiler chicken.
M Zhu, T Ruan, Q Zeng, B Wu
doaj   +2 more sources

Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI

iScience, 2023
Summary: Glucocorticoid-induced osteoporosis (GIOP) is a severe and common complication of long-term usage of glucocorticoids (GCs) and lacks of efficient therapy.
Lijuan Jiang, Wenlin Qiu, Xuefei Wang, Xiaoru Duan, Xiaoxiao Han, Tong Yu, Shenghui Wen, Zhijun Luo, Ruizhi Feng, Yao Teng, Haifeng Yin, Christian M. Hedrich, Guo-Min Deng   +12 more
doaj   +1 more source