Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
, 2020 Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima +18 more
core
IgM Augments Complement Bactericidal Activity with Serum from a Patient with a Novel CD79a Mutation [PDF]
, 2018 Antibody replacement therapy for patients with antibody deficiencies contains only IgG. As a result, concurrent IgM and IgA deficiency present in a large proportion of antibody deficient patients persists.
Burg, M. (Mirjam) van der +6 more
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A computational pipeline for the diagnosis of CVID patients [PDF]
, 2019 Common variable immunodeficiency (CVID) is one of the most frequently diagnosed primary antibody deficiencies (PADs), a group of disorders characterized by a decrease in one or more immunoglobulin (sub) classes and/or impaired antibody responses caused ...
Bogaert, Delfien +6 more
core +2 more sources
Hypogammaglobulinemia and Risk of Exacerbation and Mortality in Patients with COPD
International Journal of COPD, 2020 Are M Holm,1,2 Siw L Andreassen,3 Vivi Lycke Christensen,4– 6 Johny Kongerud,1,2 Øystein Almås,7 Henrik Auråen,2 Anne H Henriksen,8 Ingeborg S Aaberge,9 Olav Klingenberg,1,10 Tone Rustøen4,6 1Institute of Clinical Medicine,
Holm AM +9 more
doaj
Clinical characteristics and outcomes of primary antibody deficiency: A 20-year follow-up study
Journal of the Formosan Medical Association, 2014 Primary antibody deficiency is the most common disorder among primary immunodeficiencies. Recurrent infection and chronic lung change often lead to mortality and morbidity.
Hung-Yi Chan +5 more
doaj +1 more source
Health-Related Quality of Life in Patients with CVID Under Different Schedules of Immunoglobulin Administration: Prospective Multicenter Study [PDF]
, 2019 We assessed the health-related quality of life (HRQoL) in CVID adults receiving different schedules of immunoglobulin replacement therapy (IgRT) by intravenous (IVIG), subcutaneous (SCIG), and facilitated (fSCIG) preparations.
Agostini, Carlo +13 more
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Neuron-Specific HuR-Deficient Mice Spontaneously Develop Motor Neuron Disease [PDF]
, 2018 Human Ag R (HuR) is an RNA binding protein in the ELAVL protein family. To study the neuron-specific function of HuR, we generated inducible, neuron-specific HuR-deficient mice of both sexes.
Bai, Ying +10 more
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Cellular immune response to SARS-CoV-2 in patients with primary antibody deficiencies
Frontiers in Immunology, 2023 IntroductionPrimary antibody deficiencies (PAD) are inborn defects of the immune system that result in increased susceptibility to infections. Despite the reduced response to vaccination, PAD patients still benefit from it by reducing the risk of severe ...
Dorota Mizera +10 more
doaj +1 more source
IgG subclass deficiency in asthma. [PDF]
Archives of Disease in Childhood, 1988 Total immunoglobulin G (IgG) and subclasses were measured in serum samples from 82 children with chronic asthma, aged 1.5 to 6.3 years, and 76 controls. Concentrations of IgG1, IgG2, IgG3, and total IgG were significantly lower in asthmatic children aged 1 to 5, and IgG2 concentrations were also significantly lower in asthmatic children over 5 years of
B G, Loftus +3 more
openaire +2 more sources
Association of Chlamydia pneumoniae with coronary artery disease and its progression is dependent on the modifying effect of mannose-binding lectin [PDF]
, 2002 Background— The possible association between coronary artery disease (CAD) and Chlamydia pneumoniae (C pneumoniae) infection is controversial. On the basis of the recent suggestion that mannose-binding lectin (MBL) variant alleles are related to an ...
Burián, Katalin +10 more
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