Results 221 to 230 of about 474,091 (297)

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

The false-negative rate of sentinel lymph node biopsy and its related factors in early-stage cervical cancer: a systematic review and meta-analysis. [PDF]

Acta Oncol
He C, Li F, He M, Li J.
europepmc   +1 more source

Advances in GPCRs Associated With Wnt Signaling Within the Auditory System

Medicine Bulletin, EarlyView.
ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang, Changling Xu, Jiangang Fan, Renjie Chai   +3 more
wiley   +1 more source

Secretory phospholipase A₂-IIA targets bacterial extracellular vesicles to modulate immune signaling. [PDF]

Commun Biol
Doré E, Bérubé È, Greffard K, Morozumi S, Chénard V, Lemaire G, Allaeys I, Lévesque T, Rudkowska I, Brisson AR, Lambeau G, Bertrand N, Boissinot M, Arita M, Bilodeau JF, Isabel S, Boilard E.   +16 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Effect of minimally invasive surgery guided by arthrography on surgical progress, postoperative recovery and long-term prognosis of lateral humeral condyle fractures in children: a retrospective cohort study. [PDF]

Transl Pediatr
Shi S, Yu X, Ou X, Xu J, Li B, Hu D.
europepmc   +1 more source

Analytical and Numerical Soliton Solutions of the Shynaray II‐A Equation Using the G′G,1G$$ \left(\frac{G^{\prime }}{G},\frac{1}{G}\right) $$‐Expansion Method and Regularization‐Based Neural Networks

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Nonlinear differential equations play a fundamental role in modeling complex physical phenomena across solid‐state physics, hydrodynamics, plasma physics, nonlinear optics, and biological systems. This study focuses on the Shynaray II‐A equation, a relatively less‐explored parametric nonlinear partial differential equation that describes ...
Aamir Farooq, H. W. A. Riaz, Sadique Rehman, M. Mamun Miah, Wen Xiu Ma   +4 more
wiley   +1 more source

Mid-Term Results of the Multicenter CAMPARI Registry Using the E-Liac Iliac Branch Device for Aorto-Iliac Aneurysms. [PDF]

J Cardiovasc Dev Dis
Noce F, Accarino G, Angiletta D, Guercio LD, Zacà S, Massara M, Volpe P, Peluso A, Flora L, Serra R, Bracale UM.   +10 more
europepmc   +1 more source

Lp-PLA2 IIA [PDF]

, 2019
openaire   +1 more source

Unraveling the spatial landscape of dystrophinopathies: a transcriptomic approach to Becker and Duchenne muscular dystrophies

The Journal of Pathology, EarlyView.
Abstract Dystrophinopathies are caused by pathogenic variants in the DMD gene, resulting in partial (Becker) or complete loss (Duchenne) of dystrophin. Becker (BMD) and Duchenne muscular dystrophy (DMD) are characterized by progressive muscle wasting, fatty replacement, fibrosis, and loss of function.
Laura GM Heezen, Qirong Mao, Stefan Nicolau, Claudio Novella Rausell, Julia van der Weerd, Jan Kueckelhaus, Rasya Gokul Nath, Jordi Diaz‐ Manera, Hermien E Kan, Erik H Niks, Maaike van Putten, Annemieke Aartsma‐Rus, Kevin M Flanigan, Ahmed Mahfouz, Pietro Spitali   +14 more
wiley   +1 more source