Results 201 to 210 of about 474,091 (297)

Single-Nucleus Transcriptome Reveals Cellular Heterogeneity and Transcriptional Response to Heat Stress in Skeletal Muscle. [PDF]

J Cachexia Sarcopenia Muscle
Han Z, Chen L, Lei Z, Zhang J, Chen Z, Fan X, Zeng B, Jiang A, Xiang H, Li H, Li M, Jin L.   +11 more
europepmc   +1 more source

Identification of Predictive Factors for Isolated Brain Progression in Patients With Cerebral Metastatic Melanoma After Treatment With Stereotactic Brain Radiotherapy

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Melanomas often metastasize to the brain, leading to a significantly poor prognosis despite advances in local and systemic treatments. In clinical practice, we frequently observe varying response patterns and progression dynamics between cerebral and extra cerebral sites. Objectives This study aims to identify predictive factors for
Manuel Croix, Justine Lequesne, Julien Geffrelot, Anne Dompmartin, Jean Matthieu L'orphelin   +4 more
wiley   +1 more source

The Anti-Apoptotic Protein Lifeguard Is Expressed in Osteosarcoma, Chondrosarcoma, and Soft Tissue Sarcoma.

Oncology
Senger S, Schlottmann F, Strauß S, Vogt PM, Bucan V.   +4 more
europepmc   +1 more source

KRAS-Driven Hypertranscription and Metastatic Dissemination in Colorectal Cancer Could be Overcome by Targeting the NMHC IIA/ PLK1 Signaling Axis with a Novel Acridine Derivative. [PDF]

Int J Biol Sci
Ji D, Yi H, Li M, Gao Z, Yang R, Jia J, Cui X, Song C, Wang H, Shi M, Yan Y, Geng T, Meng X, Li Z, Gu J.   +14 more
europepmc   +1 more source

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

JEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson, Kara Hurley, Hannah Chaudhury, Lara Shehadeh, Cameron West   +4 more
wiley   +1 more source

From the Clinic, to the Clinic: Improving the Fluorescent Imaging Quality of ICG via Amphiphilic NIR-IIa AIE Probe. [PDF]

Biosensors (Basel)
Zhu A, Xiao Z, Sun A, Lu F, Tang H, Zhang X, Ren R, Yu W, Shao A, Feng N, Wang S, Ni J, Li Y.   +12 more
europepmc   +1 more source

Juvenile Mycosis Fungoides: A Multicenter Retrospective Italian Study

JEADV Clinical Practice, EarlyView.
This multicenter retrospective study included 29 juvenile mycosis fungoides (JMF) patients from five Italian centres with confirmed histopathological diagnosis. most often presents with hypopigmented/classic variants and CD8+ phenotype. Early‐onset cases ( < 14 years) show better long‐term outcomes.
Andrea Michelerio, Gabriele Roccuzzo, Iria Neri, Alessandro Pileri, Alessandro Svizzero, Maria Beatrice De Felici Del Giudice, Vieri Grandi, Pietro Quaglino, Valeria Brazzelli   +8 more
wiley   +1 more source

Prevalence of Colonization, Association With Disease Stage and Effect of Eradication of Staphylococcus aureus in Cutaneous T‐Cell Lymphoma: A Systematic Review and Meta‐Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Cutaneous T‐cell lymphoma (CTCL) is a rare and heterogeneous group of skin‐homing lymphomas with a largely unknown pathogenesis. Staphylococcus aureus (S. aureus) colonization has been implicated in exacerbating CTCL, particularly in advanced stages. Objectives This study assessed the prevalence of S.
Ida Lind Holm, Sarah Søltoft Rasmussen, Somaia Naassan, Misbah N. Ghazanfar, Kenneth Thomsen, Rikke Bech, Lise M. Lindahl, Maria Kamstrup, Simon Francis Thomsen, Zarqa Ali   +9 more
wiley   +1 more source

In vitro characterization of the catalytic domain of human histone deacetylase 5. [PDF]

Sci Rep
Mammen C, Hornung FM, Anzenhofer C, Schumacher J, Reiners J, Li J, Mazzone F, Bilsing FL, Kassack MU, Kurz T, Smits SHJ.   +10 more
europepmc   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source