Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling +6 more
wiley +1 more source
From intraosseous meningioma and ossified metaplastic meningioma to osteomeningioma: a novel voxel-based, atlas-normalized MRI framework for the radiological classification of skull-involving meningiomas. [PDF]
Hudelist B +15 more
europepmc +1 more source
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu +4 more
wiley +1 more source
Histone Deacetylase 7 protects against pathologic cardiac hypertrophy. [PDF]
Bu J, Hand SM, Guo S, Jang J, Li D.
europepmc +1 more source
Refining the boundaries of the nodal CTV in the middle neck for nasopharyngeal carcinoma
This study proposes fascial‐based optimizations for middle neck clinical target volume (CTV) in nasopharyngeal carcinoma (NPC), excluding the para‐pharyngeal space (PPS) and adjusting boundaries to reduce radiation volume while ensuring at‐risk nodal coverage.
Yue Deng +8 more
wiley +1 more source
Ruthenium Compounds Differentially Inhibit Group IA and IIA Snake Venom Phospholipase A<sub>2</sub> Anticoagulant Activity. [PDF]
Nielsen VG, Nielsen SA.
europepmc +1 more source
Alcoholic extracts from flowers, leaves, and shoots of Russian sage decreased downy mildew severity on grapevine leaf disks. Fractionation followed by metabolomic analysis revealed putative terpenoids as the main components of the active fractions. Specifically, 7‐methylrosmanol, 12‐O‐methylcarnosic acid, carnosic acid, and carnosol were identified as ...
Anna Smaldone +5 more
wiley +1 more source
Natural Products as Modulators of ABC Transporters in Breast Cancer
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source
"The Road Less Traveled": Endovascular Embolization of a Type II Endoleak via Corona Mortis. [PDF]
Rossini N +8 more
europepmc +1 more source
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang +16 more
wiley +1 more source

