Results 21 to 30 of about 62,434 (243)
Cell & Bioscience, 2023 Background The cilia are microtubule-based organelles that protrude from the cell surface. Abnormalities in cilia result in various ciliopathies, including polycystic kidney disease (PKD), Bardet-Biedl syndrome (BBS), and oral-facial-digital syndrome ...
Hye In Ka +6 more
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Unit-circle-preserving mappings
International Journal of Mathematics and Mathematical Sciences, 2004 We prove that if a one-to-one mapping f:ℝn→ℝn(n≥2) preserves the unit circles, then f is a linear isometry up to translation.
Soon-Mo Jung, Byungbae Kim
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IKCa channels control breast cancer metabolism including AMPK-driven autophagy
Cell Death and Disease, 2022 Ca2+-activated K+ channels of intermediate conductance (IK) are frequently overexpressed in breast cancer (BC) cells, while IK channel depletion reduces BC cell proliferation and tumorigenesis. This raises the question, of whether and mechanistically how
Dominic Gross +8 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Risicoanalyse in auditing [PDF]
MAB, 2004 Prof. Dr. K.Y. Mollema heeft mij in het MAB van december 2003 en januari/februari van 2004 aangenaam verrast (Mollema, 2003, 2004). Het is goed dat hij de discussie over risicoanalyse in de accountantscontrole weer heeft opgepakt.
H. H. W. Kloosterman
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Ik zie, ik zie wat jij niet ziet
Jeugd in Ontwikkeling, 2023 In dit proefschrift werden sociaal-cognitieve aspecten onderzocht die kunnen bijdragen aan het voortduren van chronisch pestslachtofferschap. Gepest worden heeft langdurige gevolgen, zoals meer mentale klachten, lagere schoolprestaties en zwakkere ...
Sanne Kellij +2 more
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source