Results 31 to 40 of about 65,139 (240)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Risicoanalyse in auditing [PDF]

MAB, 2004
Prof. Dr. K.Y. Mollema heeft mij in het MAB van december 2003 en januari/februari van 2004 aangenaam verrast (Mollema, 2003, 2004). Het is goed dat hij de discussie over risicoanalyse in de accountantscontrole weer heeft opgepakt.
H. H. W. Kloosterman
doaj   +3 more sources

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Enhanced solubilization and In-Vitro release of rifampicin in mixed aggregates of surface active ionic liquid and conventional surfactants

Journal of Ionic Liquids
Rifampicin is a very important drug used in the treatment of tuberculosis, but its low solubility in aqueous medium leads to its lesser bioavailability.
Ruchika, Reshu Sanan
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

EXTRACARDIAC ATHEROSCLEROTIC ARTERY DISEASE AND HELICOBACTER PYLORI INFECTION

Eurasian Journal of Medicine, 2019
There are some conflicting data on the association between Helicobacter pylori (H. pylori) infection and cardiovascular disease. In this study we investigated a possible correlation between H.
İslam Kaklıkkaya, Neşe Kaklıkkaya, Faruk Aydın, Yelda Yazıcı, Fahri Özcan   +4 more
doaj  

A comprehensive review of multifactorial determinants and predictors of malnutrition in adolescent girls

Discover Public Health
This review synthesizes research from 76 studies (2010–2025) to identify the multifactorial determinants defining malnutrition among adolescent girls.
Harminder Kaur, Pooja Sharma
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Multitarget therapeutic potential of sulforaphane in ethidium bromide-induced neurotoxicity in multiple sclerosis-like pathology: comparison with omaveloxolone and dimethyl fumarate on neuroprotection and systemic recovery

Scientific Reports
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by demyelination, neuroinflammation, and neurodegeneration. This study investigates the neuroprotective potential of Sulforaphane (SFN) in ameliorating ethidium bromide (EBRM)-induced
Divya Choudhary, Sidharth Mehan, Ritam Mukherjee, MD Nasiruddin Khan, Ghanshyam Das Gupta, Rajaram Samant, Manoj Tongra   +6 more
doaj   +1 more source