Results 221 to 230 of about 447,090 (290)

The Potential Roles of IL-1β, IL-6, and RIPK3 in the Pathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis. [PDF]

Diagnostics (Basel)
Sooranahalli C, Rao VR, Zelman B, Shekhar M, Komurlu Keceli S, Bouchard C, Iqbal O.   +6 more
europepmc   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

The effect of IL-1β inhibitor canakinumab (Ilaris®) on IL-6 production in human skeletal muscle cells. [PDF]

PLoS One
Cordeiro-Santanach A, Morales F, Parquet MDC, Uaesoontrachoon K, Rowsell J, Warford J, Wu W, Elustondo P, Hoffman EP, Nagaraju K.   +9 more
europepmc   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

SIK1 inhibits IL-1β-stimulated cartilage apoptosis and inflammation <i>in vitro</i> through the CRTC2/CREB1 signaling. [PDF]

Open Life Sci
Chen M, Ye L, Lin S.
europepmc   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Author Correction: KN3014, a piperidine-containing small compound, inhibits auto-secretion of IL-1β from PBMCs in a patient with Muckle-Wells syndrome. [PDF]

Sci Rep
Kaneko N, Kurata M, Yamamoto T, Shigemura T, Agematsu K, Yamazaki T, Takeda H, Sawasaki T, Koga T, Kawakami A, Yachie A, Migita K, Yoshiura KI, Urano T, Masumoto J.   +14 more
europepmc   +1 more source

INTERLEUKIN-1β INDUCES COMPLEMENT COMPONENT C3 AND IL-6 PRODUCTION AT THE BASOLATERAL AND APICAL MEMBRANES IN A HUMAN INTESTINAL EPITHELIAL CELL LINE

, 2000
Ryan M. Moon, Alexander A. Parikh, Timothy A. Pritts, Chris Kane, Josef E. Fischer, Andrew L. Salzman, Per-Olof Hasselgren   +6 more
openalex   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

IL-1β promotes adipogenesis by directly targeting adipocyte precursors. [PDF]

Nat Commun
Hofwimmer K, de Paula Souza J, Subramanian N, Vujičić M, Rachid L, Méreau H, Zhao C, Dror E, Barreby E, Björkström NK, Wernstedt Asterholm I, Böni-Schnetzler M, Meier DT, Donath MY, Laurencikiene J.   +14 more
europepmc   +1 more source